An improved comorbidity summary score for measuring disease burden and predicting mortality with applications to two national cohorts

Abstract

Research involving administrative healthcare data to study patient outcomes requires the investigator to account for the patient’s disease burden in order to reduce the potential for biased results. Here we develop a comorbidity summary score based on variable importance measures derived from several statistical and machine learning methods and show it has superior predictive performance to the Elixhauser and Charlson indices when used to predict 1-year, 5-year, and 10-year mortality. We used two large Veterans Administration cohorts to develop and validate the summary score and compared predictive performance using the area under ROC curve (AUC) and the Brier score.     

An asymptotic confidence interval for the process capability index Cpm

Abstract

The use of indices as an estimation tool of process capability is long-established among the statistical quality professionals. Numerous capability indices have been proposed in last few years. C_pm constitutes one of the most widely used capability indices and its estimation has attracted much interest. In this paper, we propose a new method for constructing an approximate confidence interval for the index C_pm. The proposed method is based on the asymptotic distribution of the index C_pm obtained by the Delta Method. Under some regularity conditions, the distribution of an estimator of the process capability index C_pm is asymptotically normal.     

Proposition of a General Formula for Price Indices

In this article, we propose a general formula for aggregative price indices that satisfies most postulates coming from the axiomatic price index theory. We show that the ideal Fisher index, Laspeyres and Paasche formulas, and a lot of other indices are particular cases of the proposed formula. Moreover, using the general formula we can easily define new indices, that would satisfy given postulates. We also present an interesting result for the proposed formula.     

Generalized Jackknife-Based Estimators for Univariate Extreme-Value Modeling

In this article, we revisit the importance of the generalized jackknife in the construction of reliable semi-parametric estimates of some parameters of extreme or even rare events. The generalized jackknife statistic is applied to a minimum-variance reduced-bias estimator of a positive extreme value index—a primary parameter in statistics of extremes. A couple of refinements are proposed and a simulation study shows that these are able to achieve a lower mean square error. A real data illustration is also provided.     

Zenga Distribution and Inequality Ordering

The aim of this article is to establish an ordering related to the inequality for the recently introduced Zenga distribution. In addition to the well-known order based on the Lorenz curve, the order based on I(p) curve is considered. Since the Zenga distribution seems to be suitable to model wealth, financial, actuarial, and, especially, income distributions, these findings are fundamental in the understanding of how parameter values are related to inequality. This investigation shows that for the Zenga distribution, two of the three parameters are inequality indicators.     

Time-varying clustering of multivariate longitudinal observations

Abstract

We propose a statistical method for clustering multivariate longitudinal data into homogeneous groups. This method relies on a time-varying extension of the classical K-means algorithm, where a multivariate vector autoregressive model is additionally assumed for modeling the evolution of clusters' centroids over time. Model inference is based on a least-squares method and on a coordinate descent algorithm. To illustrate our work, we consider a longitudinal dataset on human development. Three variables are modeled, namely life expectancy, education and gross domestic product.     

A hierarchy of lorenz curves based on the generalized tukey's lambda distribution

A hierarchy of Lorenz curves based on the generalized Tukey's Lambda distribution is proposed. Representations of the corresponding distribution and density function are also provided, together with popular inequality measures. Estimation methods are suggested. Finally, a comparison with other parametric families of Lorenz curves is established.     

A Similarity Measure Based on Species Proportions

ABSTRACT

There are several indices for measuring the similarity of two populations, including the ratio of the number of shared species to the number of distinct species (Jaccard's index) and the conditional probability of observing a shared species (Smith et al., 1996 Smith , W. , Solow , A. R. , Preston , P. E. ( 1996 ). An estimator of species overlap using a modified beta-binomial model. Biometrics 52 : 1472 – 1477 . [CSA] [CROSSREF] [Crossref], [Web of Science ®] , [Google Scholar]). However, these indices only take into account the number of species and species proportions of shared species. In this article, we propose a new similarity index which includes the species proportions of both the shared and non shared species in each population, and also propose a Nonparametric Maximum Likelihood Estimator (NPMLE) for this index. Bootstrap and delta methods are used to evaluate the standard errors of the NPMLE. Based on a loss function, we also compare a class of nonparametric estimators for the proposed index in various situations.     

Beyond the CPI: An Augmented Cost-of-Living Index

This note examines an augmented cost-of-living index (ACOLI) for the purpose of accounting for “augmented consumption” in real-income measures. Well-being includes not only conventional consumer purchases but also goods and services provided by employers, by mandated social regulations, and by tax-financed public goods. Because augmented consumption is often provided in ways that raise prices but not market incomes, deflating with conventional price indexes may understate real income growth. An exploratory application of the ACOLI approach to the United States during the 1960–1997 period suggests that the Consumer Price Index has grown about 19% faster than the ACOLI. This correction would reduce the estimated cost-of-living increase by .47% per year over the last 37 years.     

Estimation of firm-specific technological bias,technical change and total factor productivity growth: a dual approach

This paper deals with modeling firm-specific technical change (TC), and technological biases (inputs and scale) in estimating total factor productivity (TFP) growth. Several dual parametric econometric models are used for this purpose. We examine robustness of TFP growth and TC among competing models. These models include the traditional time trend (TT) model and the general index (GI) model. The TT and the GI models are generalized to accommodate firm-specific TC and technological bias (in inputs and output). Both nested and non-nested tests are used to select the appropriate models. Firm-level panel data from the Japanese chemical industry during 1968- 1987 is used as an application.