Mixtures of Mixtures Based on Multiresolution Analysis Theory

In this article, the approaches for exploiting mixtures of mixtures are expanded by using the Multiresolution family of probability density functions (MR pdf). The flexibility and the properties of local analysis of the MR pdf facilitate the location of subpopulations into a given population. In order to do this, two algorithms are provided.

The MR model is more flexible in adapting to the different subpopulations than the traditional mixtures. In addition, the problems of identification of mixtures distributions and the label-switching do not appear in the MR pdf context.     

Accent on Teaching Materials

Estimation of covariance components in the multivariate random-effect model with nested covariance structure is discussed. There are two covariance matrices to be estimated, namely, the between-group and the within-group covariance matrices. These two covariance matrices are most often estimated by forming a multivariate analysis of variance and equating mean square matrices to their expectations. Such a procedure involves taking the difference between the between-group mean square and the within-group mean square matrices, and often produces an estimated between-group covariance matrix that is not nonnegative definite. We present estimators of the two covariance matrices that are always proper covariance matrices. The estimators are the restricted maximum likelihood estimators if the random effects are normally distributed. The estimation procedure is extended to more complicated models, including the twofold nested and the mixed-effect models. A numerical example is presented to illustrate the use of the estimation procedure.     

The Consistent System

The Consistent System (CS) is an interactive computer system for researchers in the behavioral and policy sciences and in fields with similar requirements for data management and statistical analysis. The researcher is not expected to be a programmer. The system offers a wide range of facilities and permits the user to combine them in novel ways. In particular, tools for statistical analysis may be used in combination with a powerful relational subsystem for data base management. This paper gives an overview of the objectives, capabilities, status, and availability of the system.     

Statistical Computing: History and Trends

The evolution of computers is currently in a period of rapid change, stimulated by radically cheaper and smaller devices for processing and memory. These changes are certain to provide major opportunities and challenges for the use of computers in statistics. This article looks at history and current trends, in both general computing and statistical computing, with the goal of identifying key features and requirements for the near future. A discussion of the S language developed at Bell Laboratories illustrates some program design principles that can make future work on statistical programs more effective and more valuable.     

Frequency of Selecting Noise Variables in Subset Regression Analysis: A Simulation Study

This article presents the results of a simulation study of variable selection in a multiple regression context that evaluates the frequency of selecting noise variables and the bias of the adjusted R ² of the selected variables when some of the candidate variables are authentic. It is demonstrated that for most samples a large percentage of the selected variables is noise, particularly when the number of candidate variables is large relative to the number of observations. The adjusted R ² of the selected variables is highly inflated.     

Bayesian Binomial Regression: Predicting Survival at a Trauma Center

Standard methods for analyzing binomial regression data rely on asymptotic inferences. Bayesian methods can be performed using simple computations, and they apply for any sample size. We provide a relatively complete discussion of Bayesian inferences for binomial regression with emphasis on inferences for the probability of “success.” Furthermore, we illustrate diagnostic tools, perform model selection among nonnested models, and examine the sensitivity of the Bayesian methods.     

Nenparametric Two-Group Classification: Concepts and a SAS-Based Software Package

This article introduces BestClass, a set of SAS macros, available in the mainframe and workstation environment, designed for solving two-group classification problems using a class of recently developed nonparametric classification methods. The criteria used to estimate the classification function are based on either minimizing a function of the absolute deviations from the surface which separates the groups, or directly minimizing a function of the number of misclassified entities in the training sample. The solution techniques used by BestClass to estimate the classification rule use the mathematical programming routines of the SAS/OR software. Recently, a number of research studies have reported that under certain data conditions this class of classification methods can provide more accurate classification results than existing methods, such as Fisher's linear discriminant function and logistic regression. However, these robust classification methods have not yet been implemented in the major statistical packages, and hence are beyond the reach of those statistical analysts who are unfamiliar with mathematical programming techniques. We use a limited simulation experiment and an example to compare and contrast properties of the methods included in Best-Class with existing parametric and nonparametric methods. We believe that BestClass contributes significantly to the field of nonparametric classification analysis, in that it provides the statistical community with convenient access to this recently developed class of methods. BestClass is available from the authors.     

Chain pooling model selection for two-level fixed effects factorial experiments

As many as three iterated statistical model deletion procedures are considered for an experiment.Population model coeff cients were chosen to simulate a saturated 2⁴experiment having an unfavorable distribution of parameter values.Using random number studies, three model selection strategies were developed, namely, (1) a strategy to be used in anticipation of large coefficients of variation (neighborhood of 65 percent), (2) strategy to be used in anticipation of small coefficients of variation (4 percent or less), and (3) a security regret strategy to be used in the absence of such prior knowledge     

A network algorithm for the exact treatment of the 2×k contingency table

A common statistical problem encountered in biomedical research is to test the hypothesis that the parameters of k binomial populations are all equal. An exact test of significance of this hypothesis is possible in principle, the appropriate null distribution being a normalized product of k binomial coefficients. However, the problem of computing the tail area of this distribution can be formidable since it requires the enumeration of all sets of k binomial coefficients whose product is less than a given constant. Existing algorithms, all of which rely on explicit enumeration to generate feasible binomial coefficients     

Comparing several experimental groups with a control in the multivariate case

This paper presents a multivariate extension of Dunnett's test for comparing simultaneously k treatment group means with a single control group mean. A test based on Hotelling T²statistics is presented and approximate critical values are evaluated for the case of equal numbers of observations in each group, for the .05 and .01 levels of significance, for 1 to 5 variates, for 1 to 10 treatment groups, and for varying degrees of freedom. The accuracy of the procedure for generating approximate critical values is assessed via simulation studies conducted for selected cases and an example is presented using real data.