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71.
Abstract.  In this paper, we propose a random varying-coefficient model for longitudinal data. This model is different from the standard varying-coefficient model in the sense that the time-varying coefficients are assumed to be subject-specific, and can be considered as realizations of stochastic processes. This modelling strategy allows us to employ powerful mixed-effects modelling techniques to efficiently incorporate the within-subject and between-subject variations in the estimators of time-varying coefficients. Thus, the subject-specific feature of longitudinal data is effectively considered in the proposed model. A backfitting algorithm is proposed to estimate the coefficient functions. Simulation studies show that the proposed estimation methods are more efficient in finite-sample performance compared with the standard local least squares method. An application to an AIDS clinical study is presented to illustrate the proposed methodologies.  相似文献   
72.
对基础研究投入问题的思考   总被引:3,自引:0,他引:3  
文章首先从公共财政的角度对基础研究的投入进行分析,其次从布什和斯托克斯的科研模式角度对基础研究的投入进行分析。在此基础上对加大我国基础研究的投入提出了相关建议。  相似文献   
73.
The authors study the local influence of observations in multilevel regression models. To this end, they perturb simultaneously the variances, responses and design matrix. To measure the local change caused by these perturbations, they use generalized Cook statistics for the fixed and random parameter estimates. Closed form local influence measures also allow them to assess the joint influence of various observations. They suggest a simple computation method and illustrate their results using two examples.  相似文献   
74.
Quantifying uncertainty in the biospheric carbon flux for England and Wales   总被引:1,自引:0,他引:1  
Summary.  A crucial issue in the current global warming debate is the effect of vegetation and soils on carbon dioxide (CO2) concentrations in the atmosphere. Vegetation can extract CO2 through photosynthesis, but respiration, decay of soil organic matter and disturbance effects such as fire return it to the atmosphere. The balance of these processes is the net carbon flux. To estimate the biospheric carbon flux for England and Wales, we address the statistical problem of inference for the sum of multiple outputs from a complex deterministic computer code whose input parameters are uncertain. The code is a process model which simulates the carbon dynamics of vegetation and soils, including the amount of carbon that is stored as a result of photosynthesis and the amount that is returned to the atmosphere through respiration. The aggregation of outputs corresponding to multiple sites and types of vegetation in a region gives an estimate of the total carbon flux for that region over a period of time. Expert prior opinions are elicited for marginal uncertainty about the relevant input parameters and for correlations of inputs between sites. A Gaussian process model is used to build emulators of the multiple code outputs and Bayesian uncertainty analysis is then used to propagate uncertainty in the input parameters through to uncertainty on the aggregated output. Numerical results are presented for England and Wales in the year 2000. It is estimated that vegetation and soils in England and Wales constituted a net sink of 7.55 Mt C (1 Mt C = 1012 g of carbon) in 2000, with standard deviation 0.56 Mt C resulting from the sources of uncertainty that are considered.  相似文献   
75.
Summary. Earthquake intensities are modelled as a function of previous activity whose specific form is based on established empirical laws in seismology, but whose parameter values can vary from place to place. This model is used for characterizing regional features of seismic activities in and around Japan, and also for exploring regions where the actual seismicity rate systematically deviates from that of the modelled rate.  相似文献   
76.
阐述了企业过程再造(BPR)和核心能力的内涵及本质,分析了核心过程与核心能力二者之间的关系,指出企业过程再造不能脱离核心能力这一本质,BPR本质上应该是基于核心能力的再造。给出了基于核心能力实施BPR的6个具体步骤:即识别核心能力,识别核心过程,定义经营业绩,找出问题,确定方案和实施方案。  相似文献   
77.
新的《全日制义务教育美术课程标准(实验稿)》,要求美术教育以发展学生的艺术素养、人文素养及促进学生的发展为主要目标。新标准要求下的美术教育与传统美术教育相比,教学过程具有学生中心性、综合性、过程性、实践性、开放性、创造性、师生互动性、美育性、兴趣性和个性性等新的特征。  相似文献   
78.
Owing to the extreme quantiles involved, standard control charts are very sensitive to the effects of parameter estimation and non-normality. More general parametric charts have been devised to deal with the latter complication and corrections have been derived to compensate for the estimation step, both under normal and parametric models. The resulting procedures offer a satisfactory solution over a broad range of underlying distributions. However, situations do occur where even such a large model is inadequate and nothing remains but to consider non- parametric charts. In principle, these form ideal solutions, but the problem is that huge sample sizes are required for the estimation step. Otherwise the resulting stochastic error is so large that the chart is very unstable, a disadvantage that seems to outweigh the advantage of avoiding the model error from the parametric case. Here we analyse under what conditions non-parametric charts actually become feasible alternatives for their parametric counterparts. In particular, corrected versions are suggested for which a possible change point is reached at sample sizes that are markedly less huge (but still larger than the customary range). These corrections serve to control the behaviour during in-control (markedly wrong outcomes of the estimates only occur sufficiently rarely). The price for this protection will clearly be some loss of detection power during out-of-control. A change point comes in view as soon as this loss can be made sufficiently small.  相似文献   
79.
关系数据模型是基于记录的基本数据模型;面向对象数据模型是基于对象的基本数据模型;两种数据模型在某种程度上应存在相互映射和相互转变的可能性,它们的相互映射和相互转变将使关系数据库和面向对象数据库之间的转变成为可能。  相似文献   
80.
成人依恋研究   总被引:21,自引:0,他引:21  
依恋是人类适应生存的重要方式,是人类长期生物进化的结果,它会影响到成年后亲密关系的建立、人际社会功能的表达以及人格功能和人格特质的形成。目前成人依恋的研究大概可以分为两个方面:成人依恋的个体差异和成人依恋的检测维度。  相似文献   
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