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841.
842.
In this paper, a zero-inflated power series regression model for longitudinal count data with excess zeros is presented. We demonstrate how to calculate the likelihood for such data when it is assumed that the increment in the cumulative total follows a discrete distribution with a location parameter that depends on a linear function of explanatory variables. Simulation studies indicate that this method can provide improvements in obtaining standard errors of the estimates. We also calculate the dispersion index for this model. The influence of a small perturbation of the dispersion index of the zero-inflated model on likelihood displacement is also studied. The zero-inflated negative binomial regression model is illustrated on data regarding joint damage in psoriatic arthritis. 相似文献
843.
Yungtai Lo 《Journal of applied statistics》2012,39(10):2247-2258
Bone mineral density decreases naturally as we age because existing bone tissue is reabsorbed by the body faster than new bone tissue is synthesized. When this occurs, bones lose calcium and other minerals. What is normal bone mineral density for men 50 years and older? Suitable diagnostic cutoff values for men are less well defined than for women. In this paper, we propose using normal mixture models to estimate the prevalence of low-lumbar spine bone mineral density in men 50 years and older with or at risk for human immunodeficiency virus infection when normal values of bone mineral density are not generally known. The Box–Cox power transformation is used to determine which transformation best suits normal mixture distributions. Parametric bootstrap tests are used to determine the number of mixture components and to determine whether the mixture components are homoscedastic or heteroscedastic. 相似文献
844.
Artur J. Lemonte 《Journal of statistical planning and inference》2012,142(5):1178-1188
In this paper we obtain asymptotic expansions, up to order n−1/2 and under a sequence of Pitman alternatives, for the nonnull distribution functions of the likelihood ratio, Wald, score and gradient test statistics in the class of symmetric linear regression models. This is a wide class of models which encompasses the t model and several other symmetric distributions with longer-than normal tails. The asymptotic distributions of all four statistics are obtained for testing a subset of regression parameters. Furthermore, in order to compare the finite-sample performance of these tests in this class of models, Monte Carlo simulations are presented. An empirical application to a real data set is considered for illustrative purposes. 相似文献
845.
Bioequivalence (BE) trials play an important role in drug development for demonstrating the BE between test and reference formulations. The key statistical analysis for BE trials is the use of two one‐sided tests (TOST), which is equivalent to showing that the 90% confidence interval of the relative bioavailability is within a given range. Power and sample size calculations for the comparison between one test formulation and the reference formulation has been intensively investigated, and tables and software are available for practical use. From a statistical and logistical perspective, it might be more efficient to test more than one formulation in a single trial. However, approaches for controlling the overall type I error may be required. We propose a method called multiplicity‐adjusted TOST (MATOST) combining multiple comparison adjustment approaches, such as Hochberg's or Dunnett's method, with TOST. Because power and sample size calculations become more complex and are difficult to solve analytically, efficient simulation‐based procedures for this purpose have been developed and implemented in an R package. Some numerical results for a range of scenarios are presented in the paper. We show that given the same overall type I error and power, a BE crossover trial designed to test multiple formulations simultaneously only requires a small increase in the total sample size compared with a simple 2 × 2 crossover design evaluating only one test formulation. Hence, we conclude that testing multiple formulations in a single study is generally an efficient approach. The R package MATOST is available at https://sites.google.com/site/matostbe/ . Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
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847.
以我国电器制造企业间联盟为样本,考察了成员企业权力结构对联盟控制权不对称分布的影响.结果表明,成员企业的权力结构各因素显著影响着联盟控制权的不对称分布:内部联合权力水平会弱化这种不对称,而其冲突水平则会强化这一不对称;外部联合权力水平会显著强化这种不对称,内外部联合权力间的冲突水平也会强化这种不对称.同时,成员企业的权力结构相似性与联盟中控制权分布的不对称之间存在负相关关系,但这种关系并非线性关系,仅在成员权力结构具有高度相似性时,才会倾向于降低联盟控制权分布的不对称. 相似文献
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850.
供电行业用户满意度模型构建及实证研究 总被引:1,自引:0,他引:1
在相关理论研究基础上,构建了供电行业用户满意度模型,模型数据采集于江苏省电力公司的800位客户,并采用SAS8.1统计软件包的CALIS功能模块对模型进行了验证分析。研究结果表明:用户期望对用户感知质量、感知价值和用户满意的影响不显著,故在模型中予以删除;企业形象对用户满意和用户忠诚的影响以间接为主,直接影响不显著;修正模型中5个内生隐变量R2的平均值为0.69,经综合考虑,修正后的模型有效可靠。最后,为供电行业提升客户满意度和忠诚度提出建议。 相似文献