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181.
农业品牌化是农业工业化和现代化的重要标志,也是提高农产品质量安全水平和市场竞争力的重要途径。我国正处在农业品牌化的初级阶段,对农产品品牌竞争力评价的探讨是农业品牌化理论研究的重要组成部分,也将在实践上对农产品品牌竞争力的提高起到积极的引导和促进作用。文章经过理论分析构建了以市场评价和质量评价为主,兼顾效益评价和潜力评价的农产品品牌评价指标体系,并采用了层次分析法确定指标权重,用综合评分法确定分值,得出对农产品品牌竞争力的相对评价。  相似文献   
182.
人才素质测评方法与技术已在我国公共行政人才素质测评中得到广泛应用,但却存在着一定的缺陷和不足,即测评理论体系尚不完善、测评方法和技术欠缺科学性。因此,必须从思想理论上、测评体制及其方法、技术上加以完善,以达到更加科学的程度,才能更好地实现人才素质测评的功效。  相似文献   
183.
The organizational behavior management literature has yielded few stimulus preference assessment methodologies for use with employees. The current investigation compared three preference assessments (ranking, survey, and multiple stimulus without replacement procedures) found in the organizational behavior management literature for their ability to predict reinforcers for direct care staff members’ behavior. In the first experiment all assessments were effective for predicting reinforcers, but the results were limited by a lack of control items in the assessment. In the second experiment the survey and ranking assessments both proved to be effective for identifying reinforcers and neutral or ineffective stimuli. Implications of these results and directions for future research are discussed.  相似文献   
184.
Estimation of benchmark doses (BMDs) in quantitative risk assessment traditionally is based upon parametric dose‐response modeling. It is a well‐known concern, however, that if the chosen parametric model is uncertain and/or misspecified, inaccurate and possibly unsafe low‐dose inferences can result. We describe a nonparametric approach for estimating BMDs with quantal‐response data based on an isotonic regression method, and also study use of corresponding, nonparametric, bootstrap‐based confidence limits for the BMD. We explore the confidence limits’ small‐sample properties via a simulation study, and illustrate the calculations with an example from cancer risk assessment. It is seen that this nonparametric approach can provide a useful alternative for BMD estimation when faced with the problem of parametric model uncertainty.  相似文献   
185.
Abstract

Key controversies and diverse perspectives are summarized regarding terminology, definition, and classification issues in the field of mental retardation. Six questions are provided to guide consideration of critical issues. Conclusions are drawn and implications for professional practice are discussed.  相似文献   
186.
When assessing risks posed by environmental chemical mixtures, whole mixture approaches are preferred to component approaches. When toxicological data on whole mixtures as they occur in the environment are not available, Environmental Protection Agency guidance states that toxicity data from a mixture considered “sufficiently similar” to the environmental mixture can serve as a surrogate. We propose a novel method to examine whether mixtures are sufficiently similar, when exposure data and mixture toxicity study data from at least one representative mixture are available. We define sufficient similarity using equivalence testing methodology comparing the distance between benchmark dose estimates for mixtures in both data‐rich and data‐poor cases. We construct a “similar mixtures risk indicator”(SMRI) (analogous to the hazard index) on sufficiently similar mixtures linking exposure data with mixtures toxicology data. The methods are illustrated using pyrethroid mixtures occurrence data collected in child care centers (CCC) and dose‐response data examining acute neurobehavioral effects of pyrethroid mixtures in rats. Our method shows that the mixtures from 90% of the CCCs were sufficiently similar to the dose‐response study mixture. Using exposure estimates for a hypothetical child, the 95th percentile of the (weighted) SMRI for these sufficiently similar mixtures was 0.20 (i.e., where SMRI <1, less concern; >1, more concern).  相似文献   
187.
Abstract

The success of organ transplants is affected by the degree of antigen match between donor and recipient. With organ transplants among African Americans, finding a good antigen match is difficult. While the consent rate for organ donations among Caucasians is 50%, this rate among African Americans is only 12%. The resulting ratio of donors to “recipients” is 1 to 9 in African Americans. The majority of organs received by African Americans come from Caucasian donors, thereby reducing the probability of an antigen match and increasing the probability of organ rejection. These circumstances could be improved if the organ donation rate eamong African Americans was increased. There is some empirical support for the theory that behavior change occurs through identifiable stages. This paper presents evidence for the construct validity of a stage of change measure suitable for use in designing and evaluating attempts to promote organ donations in the African American community. Use of this measure also permits clinicians to assess how receptive a client will be to organ donation promotional material. Use of this measure offers the possibility of refining approaches to organ donations among African Americans. Increases in the donor rate will result in a larger pool of antigen compatible organs in this subpopulation.  相似文献   
188.
On incidental dermal exposure to chemicals in water, a key exposure factor is the amount of water adhering to skin. Although soil adherence factors have been developed for risk assessment, measurements of water adherence on human skin have not been described. In the Environmental Protection Agency's (EPA's) dermal risk assessment guidance, dermal dose from environmental exposures is based upon the flux rate across the skin, which assumes that an unlimited amount of chemical is available for absorption. This assumption is applicable to certain exposure scenarios such as swimming and bathing. However, exposures to contaminated water frequently involve scenarios where the available chemical is limited by the amount of water adhering to the skin, for example, during accidental splashes. We conducted studies in human volunteers to investigate water adherence per unit area of skin after brief contact with water. In two sets of experiments, either water was applied with a micropipette to 10‐cm2 areas of the lower leg, foot, and hand, or the foot and hand were briefly immersed in water. In males, using a micropipette, water adherence ranged from 1.93 (foot) to 7.13 μL/cm2 (lower leg). In females, it ranged from 1.10 (lower leg) to 4.83 μL/cm2 (hand). Hand and foot immersion resulted in relatively higher values of 6.89 and 5.17 μL/cm2, respectively, in males, and 5.40 and 6.39 μL/cm2 in females. Water adherence was affected by amount of body hair and type of exposure. Water adherence factors can be used to calculate the applied dose per unit area for exposures involving intermittent water contact.  相似文献   
189.
A model for the assessment of exposure to Listeria monocytogenes from cold-smoked salmon consumption in France was presented in the first of this pair of articles (Pouillot et al ., 2007, Risk Analysis, 27:683–700). In the present study, the exposure model output was combined with an internationally accepted hazard characterization model, adapted to the French situation, to assess the risk of invasive listeriosis from cold-smoked salmon consumption in France in a second-order Monte Carlo simulation framework. The annual number of cases of invasive listeriosis due to cold-smoked salmon consumption in France is estimated to be 307, with a very large credible interval ([10; 12,453]), reflecting data uncertainty. This uncertainty is mainly associated with the dose-response model. Despite the significant uncertainty associated with the predictions, this model provides a scientific base for risk managers and food business operators to manage the risk linked to cold-smoked salmon contaminated with L. monocytogenes. Under the modeling assumptions, risk would be efficiently reduced through a decrease in the prevalence of L. monocytogenes or better control of the last steps of the cold chain (shorter and/or colder storage during the consumer step), whereas reduction of the initial contamination levels of the contaminated products and improvement in the first steps of the cold chain do not seem to be promising strategies. An attempt to apply the recent risk-based concept of FSO (food safety objective) on this example underlines the ambiguity in practical implementation of the risk management metrics and the need for further elaboration on these concepts.  相似文献   
190.
ABSTRACT

A challenge for research with sexual-minority youth is to capture their unique stories in a way that heightens understanding of lived experience and promotes the development of culturally relevant programs and policies tailored for this population. One data collection approach that may be particularly useful for research with sexual-minority youth is the life history calendar (LHC) method. The LHC provides a visual, calendar-based assessment of life events and behaviors anchored by contextual cues to enhance retrospective recall. The purpose of this article is to examine the utility of the LHC method with sexual-minority youth and its potential to address three methodological and conceptual challenges: developmental complexity, shifting and evolving identities, and timing. The LHC method is illustrated using three studies conducted by the author as case examples. Findings suggest that the LHC offers several potential benefits for research with sexual-minority youth including its adaptable and flexible structure, capacity to assess event timing and sequence, mixed-methods capability, and its ability to engage and empower youth to co-create the interview process. Strengths and limitations of the LHC method and implications for research and practice with sexual-minority youth in a range of social service settings are discussed.  相似文献   
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