Extended BIC for linear regression models with diverging number of relevant features and high or ultra-high feature spaces

In many conventional scientific investigations with high or ultra-high dimensional feature spaces, the relevant features, though sparse, are large in number compared with classical statistical problems, and the magnitude of their effects tapers off. It is reasonable to model the number of relevant features as a diverging sequence when sample size increases. In this paper, we investigate the properties of the extended Bayes information criterion (EBIC) (Chen and Chen, 2008) for feature selection in linear regression models with diverging number of relevant features in high or ultra-high dimensional feature spaces. The selection consistency of the EBIC in this situation is established. The application of EBIC to feature selection is considered in a SCAD cum EBIC procedure. Simulation studies are conducted to demonstrate the performance of the SCAD cum EBIC procedure in finite sample cases.     

Power-divergence-type measure of departure from diagonals-parameter symmetry for square contingency tables with ordered categories

For the analysis of square contingency tables with ordered categories, Goodman considered the diagonals-parameter symmetry (DPS) model. This paper proposes a measure to represent the degree of departure from the DPS model. The proposed measure is expressed by applying Read and Cressie’s power-divergence or Patil and Taillie’s diversity index. The measure would be useful for comparing the degree of departure from the DPS model in several tables. Examples are given.     

Variance bounds for estimators in autoregressive models with constraints

We consider nonlinear and heteroscedastic autoregressive models whose residuals are martingale increments with conditional distributions that fulfil certain constraints. We treat two classes of constraints: residuals depending on the past through some function of the past observations only, and residuals that are invariant under some finite group of transformations. We determine the efficient influence function for estimators of the autoregressive parameter in such models, calculate variance bounds, discuss information gains, and suggest how to construct efficient estimators. Without constraints, efficient estimators can be given by weighted least squares estimators. With the constraints considered here, efficient estimators are obtained differently, as one-step improvements of some initial estimator, similarly as in autoregressive models with independent increments.     

Kullback–Leibler information of a censored variable and its applications

In this paper, we study the Kullback–Leibler (KL) information of a censored variable, which we will simply call it censored KL information. The censored KL information is shown to have the necessary monotonicity property in addition to inherent properties of nonnegativity and characterization. We also present a representation of the censored KL information in terms of the relative risk and study its relation with the Fisher information in censored data. Finally, we evaluate the estimated censored KL information as a goodness-of-fit test statistic.     

Analysis of hybrid censored competing risks data

In this paper, we consider the analysis of hybrid censored competing risks data, based on Cox's latent failure time model assumptions. It is assumed that lifetime distributions of latent causes of failure follow Weibull distribution with the same shape parameter, but different scale parameters. Maximum likelihood estimators (MLEs) of the unknown parameters can be obtained by solving a one-dimensional optimization problem, and we propose a fixed-point type algorithm to solve this optimization problem. Approximate MLEs have been proposed based on Taylor series expansion, and they have explicit expressions. Bayesian inference of the unknown parameters are obtained based on the assumption that the shape parameter has a log-concave prior density function, and for the given shape parameter, the scale parameters have Beta–Gamma priors. We propose to use Markov Chain Monte Carlo samples to compute Bayes estimates and also to construct highest posterior density credible intervals. Monte Carlo simulations are performed to investigate the performances of the different estimators, and two data sets have been analysed for illustrative purposes.     

Skew-normal alpha-power model

In this paper, authors study properties and inference for the newly introduced skew-normal alpha-power model, generalizing both, the power-normal and skew-normal models. Inference is approached via maximum likelihood. Fisher information matrix is derived and shown to be nonsingular at the whole parametric space. Special emphasis is placed on the special case of the power–skew-normal model. Studies with real data illustrate the fact that the model can be very useful in applications, being able to overfit less general models entertained in the literature.     

Model averaging for M-estimation

M-estimation is a widely used technique for robust statistical inference. In this paper, we study model selection and model averaging for M-estimation to simultaneously improve the coverage probability of confidence intervals of the parameters of interest and reduce the impact of heavy-tailed errors or outliers in the response. Under general conditions, we develop robust versions of the focused information criterion and a frequentist model average estimator for M-estimation, and we examine their theoretical properties. In addition, we carry out extensive simulation studies as well as two real examples to assess the performance of our new procedure, and find that the proposed method produces satisfactory results.     

Bayes designs for multiple linear regression on the unit sphere

We deal with experimental designs minimizing the mean square error of the linear BAYES estimator for the parameter vector of a multiple linear regression model where the experimental region is the k-dimensional unit sphere. After computing the uniquely determined optimum information matrix, we construct, separately for the homogeneous and the inhomogeneous model, both approximate and exact designs having such an information matrix.     

Case–control genome-wide joint association study using semiparametric empirical model and approximate Bayes factor

We propose a semiparametric approach for the analysis of case–control genome-wide association study. Parametric components are used to model both the conditional distribution of the case status given the covariates and the distribution of genotype counts, whereas the distribution of the covariates are modelled nonparametrically. This yields a direct and joint modelling of the case status, covariates and genotype counts, and gives a better understanding of the disease mechanism and results in more reliable conclusions. Side information, such as the disease prevalence, can be conveniently incorporated into the model by an empirical likelihood approach and leads to more efficient estimates and a powerful test in the detection of disease-associated SNPs. Profiling is used to eliminate a nuisance nonparametric component, and the resulting profile empirical likelihood estimates are shown to be consistent and asymptotically normal. For the hypothesis test on disease association, we apply the approximate Bayes factor (ABF) which is computationally simple and most desirable in genome-wide association studies where hundreds of thousands to a million genetic markers are tested. We treat the approximate Bayes factor as a hybrid Bayes factor which replaces the full data by the maximum likelihood estimates of the parameters of interest in the full model and derive it under a general setting. The deviation from Hardy–Weinberg Equilibrium (HWE) is also taken into account and the ABF for HWE using cases is shown to provide evidence of association between a disease and a genetic marker. Simulation studies and an application are further provided to illustrate the utility of the proposed methodology.     

General treatment of goodness-of-fit tests based on Kullback–Leibler information

This paper introduces a general goodness-of-fit test based on the estimated Kullback–Leibler information. The test uses the Vasicek entropy estimate. Two special cases of the test for location–scale and shape families are discussed. The results are used to introduce goodness-of-fit tests for the uniform, Laplace, Weibull and beta distributions. The critical values and powers for some alternatives are obtained by simulation.