Measurement Error Correction by Exploiting Gene–Environment Independence in Family‐Based Case–Control Studies

Abstract. Family‐based case–control designs are commonly used in epidemiological studies for evaluating the role of genetic susceptibility and environmental exposure to risk factors in the etiology of rare diseases. Within this framework, it is often reasonable to assume genetic susceptibility and environmental exposure being conditionally independent of each other within families in the source population. We focus on this setting to explore the situation of measurement error affecting the assessment of the environmental exposure. We correct for measurement error through a likelihood‐based method. We exploit a conditional likelihood approach to relate the probability of disease to the genetic and the environmental risk factors. We show that this approach provides less biased and more efficient results than that based on logistic regression. Regression calibration, instead, provides severely biased estimators of the parameters. The comparison of the correction methods is performed through simulation, under common measurement error structures.     

《碧岩录》宋代复音虚词考释

《碧岩录》是研究近代汉语特别是唐宋时期词汇的珍贵材料，尤其是复音词，具有很高的研究价值。其中一些唐宋时期尤其宋代新生复音虚词，很有特色，研究价值较大。通过对《碧岩录》中直饶、假饶、当头、立须、倘忽、何消、平白等十四个宋代复音虚词进行考释，《碧岩录》的语料价值可见一斑。     

内向的小佳如何变成孩子王——幼儿交往发展中的家庭影响因素典型个案研究

交往能力在个体终身成长中的作用显著，家庭是影响幼儿交往能力发展的至关重要的环境。本文通过对一则典型案例的调查访谈，梳理分析，揭示了在一个孩子交往行为发展进程中家庭因素的变化，以及可能对幼儿交往行为造成的影响。鲜活生动的事例便于身处其中的幼儿父母、幼教工作者们对照反思，以获取实用的育儿心得，对培养幼儿交往行为的发展具有一定指导和借鉴意义。     

试论乐学教育

乐学是种愉快认知、学习的心态和行为,在从中国古代教育特别是西方教育学、心理学梳理的基础上,探讨了突出学生主体、培养乐学心理、实施乐学教育的途径和方法.     

在显性与隐性之间的教师知识——论教师的“缄口知识”

波兰尼提出了缄默知识,为人类对知识的认识提供了新的视角,引起了人们的广泛关注和相关的深入研究。本文从谱系学的角度,在这种分类方法的基础上提出"缄口知识",并对教师"缄口知识"与缄默知识、教育潜规则、教育习俗进行比较,从认识论、微观政治学和价值论的视角,分析了教师"缄口知识"存在的合理性,并提出研究教师"缄口知识"有利于认识教师个体知识、解释微观教育现象和推进教育改革发展。     

德国总理安格拉·默克尔研究现状

德国现任国家总理安格拉·默克尔是国内外学者关注研究热点之一.国外研究开展较早,研究范围较广,内容涉及其生平、成长经历、政党领导、默克尔政府的对内对外政策等；国内对默克尔的研究的焦点多集中于默克尔本人生平、家庭情况的介绍方面,以及默克尔政府的对华政策及其对中德关系的影响.今后的研究或可尝试从语言学、大众传播学、新闻学等角度做出新的探索.     

Fiscal Mapping Autism Spectrum Disorder Funds: A Case Study of Ohio

Individuals with autism spectrum disorders (ASDs) have complex needs requiring regular service utilization. Policymakers, administrators, and community leaders are looking for ways to finance ASD services and systems. Understanding the fiscal resources that support ASD services is essential. This article uses fiscal mapping to explore ASD funding streams in Ohio. Fiscal mapping steps are overviewed to assist ASD stakeholders in identifying and examining ASD-related funding. Implications are drawn related to how fiscal mapping could be used to identify and leverage funding for ASD services. The resulting information is critical to utilizing existing resources, advocating for resources, and leveraging available funds.     

书号实名申领制探析——以湖北省为例

鉴于先前较为混乱的书号管理秩序及其给出版业带来的消级影响，书号实名中领制应运而生，它对于国家整合出版资源、加强宏观调控、规范市场秩序，出版社加快出版节奏、提高市场竞争都有一定的成效，但书号实名申领制在具体的运物过程中，也还存在一些弊端，因此，它还有待于进一步改进。     

王先谦《诗三家义集疏》探义

今古文两学派的较量是《诗经》问题争论史中的一大焦点,但因三家《诗》的陆续亡佚,使得后人要支持今文《诗》,得同时致力于辑佚与诠释两个工作才行,清末王先谦的《诗三家义集疏》就是这方面的名著。此书在前人的研究成果上继续前进,尽量铺陈三家原貌,以《毛诗》作为理解今文的参照系,条理清晰,而其分别家数时,主要是依照陈寿祺父子《三家诗遗说考》的成果,甚至陈氏取材不够精审的缺陷也被王氏所承续,所幸,其在面对旧有材料时仍能注意到筛选与考辨的工夫,所以呈现出来的材料仍较陈书稍显精审。     

Gay and Bisexual Men’s Experiences Using Self-Testing Kits for HIV and Rectal and Urethral Bacterial Sexually Transmitted Infections: Lessons Learned from a Study With Home-Based Testing

Abstract

Objectives: This study investigated the experiences of gay, bisexual, and other men who have sex with men (GBM) conducting HIV and sexually transmitted infection (STI) self-testing procedures. Methods: We analyzed mixed-methods data from 11 GBM who self-tested HIV-positive and 1,070 HIV-negative GBM who completed the HIV self-testing and STI self-sampling procedures. Results: Nearly all (99%) reported ease in urine-based STI self-sampling and most (90%) found rectal swab self-collection easy. Most (94%) checked their rapid-HIV self-testing results during the correct window (20-40 minutes), and nearly all (99%) trusted their HIV results. Conclusions: Recommendations for future self-testing procedures are provided based on findings from free-response data.