Comparison of One-Sided Tolerance Limits in Unbalanced One-Way Random Models

Cox's discrete logistic model was extended to the study of the life table by Thompson (1977) to handle grouped survival data. Inferences about the effect of grouping are studies byMonte Carlo methods. The results show that the effect of grouping is not substantial. This approach is applied to the grouped data on liver cancer. The computer program developed for grouped censored data with continuous and indicator covariates is of practical importance and is available fromThe Ohio State University     

Double Sampling Designs in Multivariate Linear Models with Missing Variables

We provide a method for finding the optimal double sampling plan for estimating the mean value of a continuous outcome. It is assumed that the fallible and true outcome data are related by a multivariate linear regression model where only some of the explanatory variables are sampled. Conditions under which double sampling is preferred over standard sampling plans are determined. An application of the method to a well-known data set on air pollution is presented.     

Testing the Equality of Two Proportions for Combined Unilateral and Bilateral Data

In many medical comparative studies (e.g., comparison of two treatments in an otolaryngological study), subjects may produce either bilateral (e.g., responses from a pair of ears) or unilateral (response from only one ear) data. For bilateral cases, it is meaningful to assume that the information between the two ears from the same subject are generally highly correlated. In this article, we would like to test the equality of the successful cure rates between two treatments with the presence of combined unilateral and bilateral data. Based on the dependence and independence models, we study ten test statistics which utilize both the unilateral and bilateral data. The performance of these statistics will be evaluated with respect to their empirical Type I error rates and powers under different configurations. We find that both Rosner's and Wald-type statistics based on the dependence model and constrained maximum likelihood estimates (under the null hypothesis) perform satisfactorily for small to large samples and are hence recommended. We illustrate our methodologies with a real data set from an otolaryngology study.     

Estimation of the additive hazards model with interval-censored data and missing covariates

The additive hazards model is one of the most commonly used regression models in the analysis of failure time data and many methods have been developed for its inference in various situations. However, no established estimation procedure exists when there are covariates with missing values and the observed responses are interval-censored; both types of complications arise in various settings including demographic, epidemiological, financial, medical and sociological studies. To address this deficiency, we propose several inverse probability weight-based and reweighting-based estimation procedures for the situation where covariate values are missing at random. The resulting estimators of regression model parameters are shown to be consistent and asymptotically normal. The numerical results that we report from a simulation study suggest that the proposed methods work well in practical situations. An application to a childhood cancer survival study is provided. The Canadian Journal of Statistics 48: 499–517; 2020 © 2020 Statistical Society of Canada     

Inferactive data analysis

We describe inferactive data analysis, so-named to denote an interactive approach to data analysis with an emphasis on inference after data analysis. Our approach is a compromise between Tukey's exploratory and confirmatory data analysis allowing also for Bayesian data analysis. We see this as a useful step in concrete providing tools (with statistical guarantees) for current data scientists. The basis of inference we use is (a conditional approach to) selective inference, in particular its randomized form. The relevant reference distributions are constructed from what we call a DAG-DAG—a Data Analysis Generative DAG, and a selective change of variables formula is crucial to any practical implementation of inferactive data analysis via sampling these distributions. We discuss a canonical example of an incomplete cross-validation test statistic to discriminate between black box models, and a real HIV dataset example to illustrate inference after making multiple queries on data.     

Probabilistic frontier regression models for binary type output data

This paper proposes a probabilistic frontier regression model for binary type output data in a production process setup. We consider one of the two categories of outputs as ‘selected’ category and the reduction in probability of falling in this category is attributed to the reduction in technical efficiency (TE) of the decision-making unit. An efficiency measure is proposed to determine the deviations of individual units from the probabilistic frontier. Simulation results show that the average estimated TE component is close to its true value. An application of the proposed method to the data related to the Indian public sector banking system is provided where the output variable is the indicator of level of non-performing assets. Individual TE is obtained for each of the banks under consideration. Among the public sector banks, Andhra bank is found to be the most efficient, whereas the United Bank of India is the least.     

A class of additive transformation models for recurrent gap times

Abstract

The gap time between recurrent events is often of primary interest in many fields such as medical studies, and in this article, we discuss regression analysis of the gap times arising from a general class of additive transformation models. For the problem, we propose two estimation procedures, the modified within-cluster resampling (MWCR) method and the weighted risk-set (WRS) method, and the proposed estimators are shown to be consistent and asymptotically follow the normal distribution. In particular, the estimators have closed forms and can be easily determined, and the methods have the advantage of leaving the correlation among gap times arbitrary. A simulation study is conducted for assessing the finite sample performance of the presented methods and suggests that they work well in practical situations. Also the methods are applied to a set of real data from a chronic granulomatous disease (CGD) clinical trial.     

中国基本医疗保险的实际参保率及其分布特征:基于多源数据的分析

全民覆盖是基本医疗保险降低国民医疗费用负担的前提条件。中国基本医疗保险是否实现了全民覆盖仍存在争议。本文利用多源调查数据,分析了我国基本医疗保险实际参保率及其分布特征。不同来源的数据基本证实,2015-2016年,中国仍有超过10%的国民没有参加任何一项基本医疗保险制度。其中,城镇居民、非农户口和没有户口的居民、东北地区、年轻人、儿童、未就业人群、低收入人群、在校学生以及流动人口基本医疗保险实际参保率更低。城乡居民实行自愿参保,因管理部门分割、信息系统不统一导致的重复参保以及因财政补贴制度导致的户籍地参保等制度设计,是导致基本医疗保险未能实现全民覆盖的根源。要实现基本医疗保险全民覆盖,解决国民医疗后顾之忧,未来我国基本医疗保险应实行强制参保、以家庭为单元参保、常住地参保,建立全国统一的基本医疗保险信息系统,并鼓励发展补充性医疗保障制度。     

Estimation of system reliability for exponential distributions based on L ranked set sampling

Abstract

In the case where strength and stress both follow exponential distributions, this paper considers the maximum likelihood estimator (MLE) of the system reliability based on L ranked set sampling (LRSS). The proposed MLE is shown to have existence, uniqueness and asymptotic normality, and its asymptotic variance is obtained by the Fisher information matrix of LRSS. The values of asymptotic relative efficiencies show that the proposed MLE is always more efficient than the MLE using simple random sampling (SRS). However, the MLE using LRSS cannot be written in closed form. Therefore, the modified MLE is proposed using the technique replaced some terms in the maximum likelihood equations by their expectations. The newly modified MLE using LRSS is shown to be superior to the MLE using SRS. Finally, the proposed method is applied to a real data set on metastatic renal carcinoma study.     

Tests for homogeneity of risk differences in stratified design with correlated bilateral data

ABSTRACT

Correlated bilateral data arise from stratified studies involving paired body organs in a subject. When it is desirable to conduct inference on the scale of risk difference, one needs first to assess the assumption of homogeneity in risk differences across strata. For testing homogeneity of risk differences, we herein propose eight methods derived respectively from weighted-least-squares (WLS), the Mantel-Haenszel (MH) estimator, the WLS method in combination with inverse hyperbolic tangent transformation, and the test statistics based on their log-transformation, the modified Score test statistic and Likelihood ratio test statistic. Simulation results showed that four of the tests perform well in general, with the tests based on the WLS method and inverse hyperbolic tangent transformation always performing satisfactorily even under small sample size designs. The methods are illustrated with a dataset.