Bayesian optimal sequential design for nonparametric regression via inhomogeneous evolutionary MCMC

We develop a novel computational methodology for Bayesian optimal sequential design for nonparametric regression. This computational methodology, that we call inhomogeneous evolutionary Markov chain Monte Carlo, combines ideas of simulated annealing, genetic or evolutionary algorithms, and Markov chain Monte Carlo. Our framework allows optimality criteria with general utility functions and general classes of priors for the underlying regression function. We illustrate the usefulness of our novel methodology with applications to experimental design for nonparametric function estimation using Gaussian process priors and free-knot cubic splines priors.     

Maximum likelihood estimation for generalized conditionally autoregressive models of spatial data

Conditionally autoregressive (CAR) models are often used to analyze a spatial process observed over a lattice or a set of irregular regions. The neighborhoods within a CAR model are generally formed deterministically using the inter-distances or boundaries between the regions. To accommodate directional and inherent anisotropy variation, a new class of spatial models is proposed that adaptively determines neighbors based on a bivariate kernel using the distances and angles between the centroid of the regions. The newly proposed model generalizes the usual CAR model in a sense of accounting for adaptively determined weights. Maximum likelihood estimators are derived and simulation studies are presented for the sampling properties of the estimates on the new model, which is compared to the CAR model. Finally the method is illustrated using a data set on the elevated blood lead levels of children under the age of 72 months observed in Virginia in the year of 2000.     

Testing variance components in balanced linear growth curve models

It is well known that the testing of zero variance components is a non-standard problem since the null hypothesis is on the boundary of the parameter space. The usual asymptotic chi-square distribution of the likelihood ratio and score statistics under the null does not necessarily hold because of this null hypothesis. To circumvent this difficulty in balanced linear growth curve models, we introduce an appropriate test statistic and suggest a permutation procedure to approximate its finite-sample distribution. The proposed test alleviates the necessity of any distributional assumptions for the random effects and errors and can easily be applied for testing multiple variance components. Our simulation studies show that the proposed test has Type I error rate close to the nominal level. The power of the proposed test is also compared with the likelihood ratio test in the simulations. An application on data from an orthodontic study is presented and discussed.     

Two non parametric methods for change-point detection in distribution

The change-point detection problem is determining whether a change has taken place. Two non parametric methods based on empirical likelihood and the likelihood ratio are proposed for detecting a change-point problem in distributions for independent observations. Numerical studies are carried out to evaluate the performance of the proposed methods. The simulation results demonstrate that the proposed methods are robust, that is, they perform well regardless of whether the observations are from the same distribution family.     

Composite Estimation for Single‐Index Models with Responses Subject to Detection Limits

We propose a semiparametric estimator for single‐index models with censored responses due to detection limits. In the presence of left censoring, the mean function cannot be identified without any parametric distributional assumptions, but the quantile function is still identifiable at upper quantile levels. To avoid parametric distributional assumption, we propose to fit censored quantile regression and combine information across quantile levels to estimate the unknown smooth link function and the index parameter. Under some regularity conditions, we show that the estimated link function achieves the non‐parametric optimal convergence rate, and the estimated index parameter is asymptotically normal. The simulation study shows that the proposed estimator is competitive with the omniscient least squares estimator based on the latent uncensored responses for data with normal errors but much more efficient for heavy‐tailed data under light and moderate censoring. The practical value of the proposed method is demonstrated through the analysis of a human immunodeficiency virus antibody data set.     

The Kumaraswamy skew-t distribution and its related properties

Skew normal distribution is an alternative distribution to the normal distribution to accommodate asymmetry. Since then extensive studies have been done on applying Azzalini’s skewness mechanism to other well-known distributions, such as skew-t distribution, which is more flexible and can better accommodate long tailed data than the skew normal one. The Kumaraswamy generalized distribution (Kw ? F) is another new class of distribution which is capable of fitting skewed data that can not be fitted well by existing distributions. Such a distribution has been widely studied and various versions of generalization of this distribution family have been introduced. In this article, we introduce a new generalization of the skew-t distribution based on the Kumaraswamy generalized distribution. The new class of distribution, which we call the Kumaraswamy skew-t (KwST) has the ability of fitting skewed, long, and heavy-tailed data and is more flexible than the skew-t distribution as it contains the skew-t distribution as a special case. Related properties of this distribution family such as mathematical properties, moments, and order statistics are discussed. The proposed distribution is applied to a real dataset to illustrate the estimation procedure.     

Bayesian estimation and prediction for Weibull model with progressive censoring

This article presents the statistical inferences on Weibull parameters with the data that are progressively type II censored. The maximum likelihood estimators are derived. For incorporation of previous information with current data, the Bayesian approach is considered. We obtain the Bayes estimators under squared error loss with a bivariate prior distribution, and derive the credible intervals for the parameters of Weibull distribution. Also, the Bayes prediction intervals for future observations are obtained in the one- and two-sample cases. The method is shown to be practical, although a computer program is required for its implementation. A numerical example is presented for illustration and some simulation study are performed.     

Spectral Estimation of Covolatility from Noisy Observations Using Local Weights

We propose localized spectral estimators for the quadratic covariation and the spot covolatility of diffusion processes, which are observed discretely with additive observation noise. The appropriate estimation for time‐varying volatilities is based on an asymptotic equivalence of the underlying statistical model to a white‐noise model with correlation and volatility processes being constant over small time intervals. The asymptotic equivalence of the continuous‐time and discrete‐time experiments is proved by a construction with linear interpolation in one direction and local means for the other. The new estimator outperforms earlier non‐parametric methods in the literature for the considered model. We investigate its finite sample size characteristics in simulations and draw a comparison between various proposed methods.     

Shared frailty model based on reversed hazard rate for left censored data

Frailty models are used in the survival analysis to account for the unobserved heterogeneity in the individual risks to disease and death. To analyze the bivariate data on related survival times (e.g., matched pairs experiments, twin or family data), the shared frailty models were suggested. In this article, we introduce the shared gamma frailty models with the reversed hazard rate. We develop the Bayesian estimation procedure using the Markov chain Monte Carlo (MCMC) technique to estimate the parameters involved in the model. We present a simulation study to compare the true values of the parameters with the estimated values. We apply the model to a real life bivariate survival dataset.     

An overlook on statistical inference issues for stochastic damping hamiltonian systems under the fluctuation-dissipation condition

ABSTRACT

In this paper, we are interested in nonparametric inference issues for stochastic damping hamiltonian systems under the fluctuation-dissipation condition. This condition relates the magnitude of the dissipative term and the magnitude of the random term. The precise balance between the drift term which removes energy in average and the stochastic term provided by the fluctuation-dissipation relation insures that the canonical measure is preserved by the dynamics. In this framework, it is possible to give an explicit construction of a Lyapunov function and thus to prove exponential ergodicity. Then, we consider various estimation procedures and provide also a numerical section, where simulations are conducted.