Efficient heterogeneous sampling for stochastic simulation with an illustration in health care applications

In modeling disease transmission, contacts are assumed to have different infection rates. A proper simulation must model the heterogeneity in the transmission rates. In this article, we present a computationally efficient algorithm that can be applied to a population with heterogeneous transmission rates. We conducted a simulation study to show that the algorithm is more efficient than other algorithms for sampling the disease transmission in a subset of the heterogeneous population. We use a valid stochastic model of pandemic influenza to illustrate the algorithm and to estimate the overall infection attack rates of influenza A (H1N1) in a Canadian city.     

基于支持向量机的管理信息系统故障识别模型研究

管理信息系统故障影响着企业信息工程的开展。及时识别故障,能够为企业争取更多时间处理故障。因此,管理信息系统故障识别有着重要的研究意义和实践意义。基于支持向量机,构建管理信息系统故障识别模型,通过把样本应用于该模型,结果表明该模型具有较好的准确性,能有效识别管理信息系统故障。     

Access to justice for Aboriginal People in the Northern Territory

This article discusses research in the Northern Territory on Aboriginal civil and family law needs. It is based on focus group discussions and interviews with legal services providers and other associated organisations. The article argues that key areas of legal need involve discrimination, housing, child protection, social security, credit/debt and consumer law problems. It further argues that welfare conditionality, particularly as embodied in the NT Intervention and subsequent Stronger Futures policies, has exacerbated the need for legal assistance and advocacy for Aboriginal people.     

A Tiered Framework for Risk‐Relevant Characterization and Ranking of Chemical Exposures: Applications to the National Children's Study (NCS)

A challenge for large‐scale environmental health investigations such as the National Children's Study (NCS), is characterizing exposures to multiple, co‐occurring chemical agents with varying spatiotemporal concentrations and consequences modulated by biochemical, physiological, behavioral, socioeconomic, and environmental factors. Such investigations can benefit from systematic retrieval, analysis, and integration of diverse extant information on both contaminant patterns and exposure‐relevant factors. This requires development, evaluation, and deployment of informatics methods that support flexible access and analysis of multiattribute data across multiple spatiotemporal scales. A new “Tiered Exposure Ranking” (TiER) framework, developed to support various aspects of risk‐relevant exposure characterization, is described here, with examples demonstrating its application to the NCS. TiER utilizes advances in informatics computational methods, extant database content and availability, and integrative environmental/exposure/biological modeling to support both “discovery‐driven” and “hypothesis‐driven” analyses. “Tier 1” applications focus on “exposomic” pattern recognition for extracting information from multidimensional data sets, whereas second and higher tier applications utilize mechanistic models to develop risk‐relevant exposure metrics for populations and individuals. In this article, “tier 1” applications of TiER explore identification of potentially causative associations among risk factors, for prioritizing further studies, by considering publicly available demographic/socioeconomic, behavioral, and environmental data in relation to two health endpoints (preterm birth and low birth weight). A “tier 2” application develops estimates of pollutant mixture inhalation exposure indices for NCS counties, formulated to support risk characterization for these endpoints. Applications of TiER demonstrate the feasibility of developing risk‐relevant exposure characterizations for pollutants using extant environmental and demographic/socioeconomic data.     

Bayesian estimation of rare sensitive attribute

Randomized response models have been used to estimate a population proportion of a sensitive attribute. A randomized device is typically employed to protect respondent's privacy in a survey. In addition, an unrelated question is asked to improve the statistical efficiency. In this article, we propose Bayesian estimation of rare sensitive attribute using randomized response technique, which includes a rare unrelated attribute. Two cases are considered, the proportion of a rare unrelated attribute is known and unknown. A simulation study is conducted to assess the performance of the models using mean absolute error and coverage probability. The results show that the performance depends on the parameters and is robust to priors.     

A new confidence interval in errors-in-variables model with known error variance

This paper considers constructing a new confidence interval for the slope parameter in the structural errors-in-variables model with known error variance associated with the regressors. Existing confidence intervals are so severely affected by Gleser–Hwang effect that they are subject to have poor empirical coverage probabilities and unsatisfactory lengths. Moreover, these problems get worse with decreasing reliability ratio which also result in more frequent absence of some existing intervals. To ease these issues, this paper presents a fiducial generalized confidence interval which maintains the correct asymptotic coverage. Simulation results show that this fiducial interval is slightly conservative while often having average length comparable or shorter than the other methods. Finally, we illustrate these confidence intervals with two real data examples, and in the second example some existing intervals do not exist.     

The Romance of Surrogacy1

This article seeks to demonstrate and analyze the cultural and emotional work surrogate mothers collectively engage in on the largest surrogacy support website, http://www.surromomsonline.com . Surrogate mothers’ online stories and discussions frame contract surrogacy as a “labor of love.” Women often describe their surrogacy as a “journey” of shared love; they hope for a lasting relationship with the couple they carry for. This article explores how the language of love, learned and internalized through online communication with other surrogates, creates both a cultural conceptualization of surrogacy and a ground for action. Love and altruistic giving are consistent with close interpersonal rather than market relationships; surrogates hope for a long‐term friendship with their couple. Surrogacy journeys, however, not infrequently end in disappointment; surrogates feel betrayed when couples cut ties. As a result of collective learning, surrogates’ discussions increasingly articulate the position that love, even when unreciprocated, can lead to repeated giving; love is noble and ennobling. Surrogates find appreciation and support in their online surrogacy community where they agree that giving life is a moral good. This stance has contributed to a renewed enthusiasm to bear children for others.     

Corrected maximum likelihood estimators in heteroscedastic symmetric nonlinear models

In this article, we derive general matrix formulae for second-order biases of maximum likelihood estimators (MLEs) in a class of heteroscedastic symmetric nonlinear regression models, thus generalizing some results in the literature. This class of regression models includes all symmetric continuous distributions, and has a wide range of practical applications in various fields such as engineering, biology, medicine and economics, among others. The variety of distributions with different kurtosis coefficients than the normal may give more flexibility in the choice of an appropriate distribution, particularly to accommodate outlying and influential observations. We derive a joint iterative process for estimating the mean and dispersion parameters. We also present simulation studies for the biases of the MLEs.     

On the enumeration of rectangular (0, 1)-matrices

The construction and enumeration of (0, 1)-matrices with given line-sums is described for the rectangular cases often encountered in applications. Improved approximations are provided for the number of such matrices. Some new enumeration results for semi-regular bipartite graphs are included, and the related category of the quasi-semiregular bipartite graphs is recognized. The range of certain elements of products of a (0, I)-matrix is considered as a function of the line-sums. This, in turn, is related to the range in the numbers of interchanges available. Improvements in statistical practice that come from these constructions and enumerations are described.