高师技法课改革的专业特殊性与科学性

本文从高师技法课(声乐、钢琴)教学改革的大潮中,提出了教学改革中应注意专业的特殊性和科学性,阐述了教学改革应遵循的基本原则以及合理的课型模式。     

Estimation of Metabolic Rate Constants in PBPK‐Models from Liver Slice Experiments: What Are the Experimental Needs?

A mechanistic model is presented describing the clearance of a compound in a precision-cut liver slice that is incubated in a culture medium. The problem of estimating metabolic rate constants in PBPK models from liver slice experiments is discussed using identifiability analysis. From the identifiability problem analysis, it appears that in addition to the clearance, the compound's free fraction in the slice and the diffusion rate of the exchange of the compound between culture medium and liver slice should be identified. In addition, knowledge of the culture medium volume, the slice volume, the compound's free fraction, and octanol-water-based partition between medium and slice is presupposed. The formal solution for identification is discussed from the perspective of experimental practice. A formally necessary condition for identification is the sampling of parent compound in liver slice or culture medium. However, due to experimental limitations and errors, sampling the parent compound in the slice together with additional sampling of metabolite pooled from the medium and the slice is required for identification in practice. Moreover, it appears that identification results are unreliable when the value of the intrinsic clearance exceeds the value of the diffusion coefficient, a condition to be verified a posteriori.     

非拓扑孤子模型的相变特征与袋常数的温度依赖性

本文计算了在有限温度和密度下非拓扑孤子模型的有效势;得到了袋常数对温度和化学势的依赖关系;分析了禁闭解除相变的特征.结果表明:该模型的禁闭解除相变为一级;相变特征的分析表明有退禁闭相与禁闭相的两相共存.     

一般Gauss－Markov模型下一般可估函数的线性充分性和线性完全性

发展了Ｂａｋｓａｌａｒｙ和Ｄｒｙｇａｓ提出的一般Ｇａｕｓｓ－Ｍａｒｋｏｖ模型中线性充分性、最小充分性和完全性的概念，用Ｒａｏ的最小二乘统一理论，给出了这些概念的刻划定理。     

Uncertainty Analysis for Computer Model Projections of Hurricane Losses

Projecting losses associated with hurricanes is a complex and difficult undertaking that is wrought with uncertainties. Hurricane Charley, which struck southwest Florida on August 13, 2004, illustrates the uncertainty of forecasting damages from these storms. Due to shifts in the track and the rapid intensification of the storm, real-time estimates grew from 2 to 3 billion dollars in losses late on August 12 to a peak of 50 billion dollars for a brief time as the storm appeared to be headed for the Tampa Bay area. The storm hit the resort areas of Charlotte Harbor near Punta Gorda and then went on to Orlando in the central part of the state, with early poststorm estimates converging on a damage estimate in the 28 to 31 billion dollars range. Comparable damage to central Florida had not been seen since Hurricane Donna in 1960. The Florida Commission on Hurricane Loss Projection Methodology (FCHLPM) has recognized the role of computer models in projecting losses from hurricanes. The FCHLPM established a professional team to perform onsite (confidential) audits of computer models developed by several different companies in the United States that seek to have their models approved for use in insurance rate filings in Florida. The team's members represent the fields of actuarial science, computer science, meteorology, statistics, and wind and structural engineering. An important part of the auditing process requires uncertainty and sensitivity analyses to be performed with the applicant's proprietary model. To influence future such analyses, an uncertainty and sensitivity analysis has been completed for loss projections arising from use of a Holland B parameter hurricane wind field model. Uncertainty analysis quantifies the expected percentage reduction in the uncertainty of wind speed and loss that is attributable to each of the input variables.     

论政治语言的结构

分析和研究政治语言的系统结构及结构要素之间的相互关系 ,是研究政治语言的重要内容 ,有利于更好地认识和把握政治语言。政治语言结构是一种特殊的层级系统 ,其要素包括符号、符号系统、符码、文本、语境和话语。政治语言结构的要素之间相互作用、相互关联 ,共同构成了政治语言的系统 ,并以其特有的方式表达政治意义 ,服务于政治活动     

两相交流伺服电机动态性能的研究

对于两相交流电机的速度伺服系统,分析在幅值控制时系统的机械特性与调节特性,提出了影响两相交流伺服电机动态性能的因素是系统的机械时间常数及增益系数的变化。为了防止因机械时间常数及增益系数的变化而引起的动态特性变差,采用一种简易跟随模型参考自适应控制方法,通过模型与自适应机构的调节作用,改善两相交流伺服电机系统的动态特性和控制精度。计算机仿真结果表明,电机的动态持性良好。     

网络环境下的学习模式探索

教育模式是教育观念、教育思想、教与学理论的集中体现,网络的出现为学习者提供了适应个性化需求的自主学习的机会,建立满足不同学生需要的网络学习模式,是网络教学的当务之急。     

建筑节能激励政策的非对称博弈分析

本文探讨了建筑节能领域中政府与房地产商群体之间的非对称博弈问题,分析了该博弈所具有的模仿者动态模型、斯坦克尔伯格模型的特点,并构造了两者关于建筑节能激励政策的非对称博弈模型,最后对双方分别提出了博弈策略建议。     

On pooling data summaries in the absence of interactions “response-by-study”

The standard hypothesis testing procedure in meta-analysis (or multi-center clinical trials) in the absence of treatment-by-center interaction relies on approximating the null distribution of the standard test statistic by a standard normal distribution. For relatively small sample sizes, the standard procedure has been shown by various authors to have poor control of the type I error probability, leading to too many liberal decisions. In this article, two test procedures are proposed, which rely on thet—distribution as the reference distribution. A simulation study indicates that the proposed procedures attain significance levels closer to the nominal level compared with the standard procedure.