In many diagnostic studies, multiple diagnostic tests are performed on each subject or multiple disease markers are available. Commonly, the information should be combined to improve the diagnostic accuracy. We consider the problem of comparing the discriminatory abilities between two groups of biomarkers. Specifically, this article focuses on confidence interval estimation of the difference between paired AUCs based on optimally combined markers under the assumption of multivariate normality. Simulation studies demonstrate that the proposed generalized variable approach provides confidence intervals with satisfying coverage probabilities at finite sample sizes. The proposed method can also easily provide P-values for hypothesis testing. Application to analysis of a subset of data from a study on coronary heart disease illustrates the utility of the method in practice. 相似文献
ABSTRACTGuided by the Person-Environment Fit perspective, we investigated the extent to which personal and environmental factors influence depression among community-dwelling adults. The data came from the special section about community-based service utilization in the 2012 Health and Retirement Study (N=1,710). Although community-based service was not significantly associated with depression after controlling for covariates, respondents with functional limitations and living alone were less likely to be depressed when using community-based services. This study demonstrates the different associations between community-based services and depression depending on personal needs. It discusses the importance of community-based services for aging-in-place policy, particularly among vulnerable populations. 相似文献
ABSTRACTDrawing on digitaltrace data, publicly accessible government documents, and journalistic reports, this research integrates Beck’s risk society theory with digital media theories to examine the mediated process of risk definition and assessment of PM2.5 (particulate matters with a diameter less than 2.5 micrometers) in a networked public sphere. Network and content analysis of a PM2.5 Twitter network shows that political and professional elite remained the most powerful producers of risk definition. Established media played a key role, yet faced challenges from a variety of actors who disseminated and filtered information. Laypersons, while peripheral, actively interacted with elite and established media. The blurring geographic boundary in the PM2.5 Twitter network revealed an emerging transnational public sphere, which, however, was segregated by language. This research advances a layered understanding of the contingent, paradoxical media impact for social changes in a risk society. 相似文献
This study aims to identify the challenges and approaches to improve a multicultural competency among teachers in multi-ethnic schools environment based on school leaders’ perspective. Data collection method used in this study is qualitative method. A total of nine school leaders from the states of Kedah, Penang, and Perak were included in the interview session. The results of this study show that the challenges faced by teachers in practicing the multicultural competency are lack of experience toward cultural diversity. A late exposure to cultural diversity makes it difficult for teachers to accept and adapt in a multi-ethnic school environment. The approaches suggested by school leaders to improve the multicultural competency are as follows: (1) Courses on cultural diversity should be organized to enhance the knowledge about cultural diversity; (2) the development of more open and better policy for education system in Malaysia in order to prepare teachers with a higher multicultural competency for teaching students from diverse ethnic and cultural groups; (3) an early exposure to cultural diversity in order to increase the multicultural competency, especially during teaching practicum. 相似文献
In this cross-sectional study, we tested the relationship between sociophysical environment, quality of life (QOL), and perceived social support among elderly in Iran. The sample includes 128 participants recruited in the city of Shahrekord, Iran. We measured Evaluation of Older People Living Environment (EVOLVE); Control, Autonomy, Self-realization and Pleasure scale (CASP-19) and Multidimensional Scale of Perceived Social Support (MSPSS) tools respectively, through home-based observation and interview. A significant relationship was found between several domains of home environment, QOL, and perceived social support. The interaction effect of the home environment and gender in relation to QOL and perceived social support was statistically significant. Our results support that the home physical environment may not be considered a strong predictor of QOL among the Iranian elderly. 相似文献
Background: The majority of people with dementia are cared for by their families at home. This study aimed to elicit family carers' perceptions on home environmental aspects and strategies with the view to identify barriers and facilitators when caring for a person with dementia at home.
Design and methods: Thirteen co-resident family carers were engaged in semi-structured in-depth walking interviews. Interviews were recorded, transcribed and analysed using thematic analysis.
Results: Home environments can pose a number of challenges and opportunities. Aspects of the architectural and interior environment (e.g. size, condition, layout and accessibility, familiarity) are perceived as important (Theme 1) as well as a plethora of environmental strategies that encourage independence and comfort at home (Theme 2). Carers' scepticism, timing, costs, property characteristics and mistrust to services are some barriers to implementing environmental strategies (Theme 3).
Conclusions: Carers improvised solutions via trial and error and need further education on strategies to create an enabling and comfortable home environment. 相似文献
The objective is to test if religiosity affects environmental opinion in Europe. Using data from European Social Survey (ESS) 2002/2003, the study answers three questions. At the societal level: Is public opinion about the environment different in political systems with different Christian traditions? Is environmental concern less or higher in the public opinion depending on the degree of secularization in the political systems? At the individual level: Is the environmental opinion of the individual affected by the personal confession of faith, religious involvement, and the dominant religious context? At the societal level, the findings show stronger concern for the environment in Catholic and Eastern Orthodox countries than in Protestant countries. The tendency also shows a weakened concern for the environment in countries with a rather secular population. At the individual level, there are significant positive effects on environmental care from Catholic culture, negative effect from Protestant culture, and no effect from religious involvement. 相似文献