Comparing Two Population Means and Variances: A Parametric Robust Way

Abstract

This article introduces a parametric robust way of comparing two population means and two population variances. With large samples the comparison of two means, under model misspecification, is lesser a problem, for, the validity of inference is protected by the central limit theorem. However, the assumption of normality is generally required, so that the inference for the ratio of two variances can be carried out by the familiar F statistic. A parametric robust approach that is insensitive to the distributional assumption will be proposed here. More specifically, it will be demonstrated that the normal likelihood function can be adjusted for asymptotically valid inferences for all underlying distributions with finite fourth moments. The normal likelihood function, on the other hand, is itself robust for the comparison of two means so that no adjustment is needed.     

On estimating the dimensionality in discriminant analysis

In discriminant analysis, the dimension of the hyperplane which population mean vectors span is called the dimensionality. The procedures commonly used to estimate this dimension involve testing a sequence of dimensionality hypotheses as well as model fitting approaches based on (consistent) Akaike's method, (modified) Mallows' method and Schwarz's method. The marginal log-likelihood (MLL) method is developed and the asymptotic distribution of the dimensionality estimated by this method for normal populations is derived. Furthermore a modified marginal log-likelihood (MMLL) method is also considered. The MLL method is not consistent for large samples and two modified criteria are proposed which attain asymptotic consistency. Some comments are made with regard to the robustness of this method to departures from normality. The operating characteristics of the various methods proposed are examined and compared.     

On the sample breakdown robustness of some nonparametric tests

In this paper, relying on the sample breakdown points, we investigate the sample breakdown properties of some nonparametric tests. It is shown that the sample breakdown points of the sign test asymptotically dominate those of the Wilcoxon test for one–sided hypotheses, However, the different conclusion is derived in the case of testing some shrinking neighborhood hypotheses. The breakdown behaviors of the Kolmogorov test and X²–test are also explored. These studies unify or refine some existing breakdown analyses of tests.     

Kolmogorov-type tests of goodness-of-fit against stochastic ordering

This article addresses the problem of testing the null hypothesis H₀ that a random sample of size n is from a distribution with the completely specified continuous cumulative distribution function F_n(x). Kolmogorov-type tests for H₀ are based on the statistics C⁺ _n = Sup[F_n(x)?F₀(x)] and C^? _n=Sup[F₀(x)?F_n(x)], where F_n(x) is an empirical distribution function. Let F(x) be the true cumulative distribution function, and consider the ordered alternative H₁: F(x)≥F₀(x) for all x and with strict inequality for some x. Although it is natural to reject H₀ and accept H₁ if C ⁺ _n is large, this article shows that a test that is superior in some ways rejects F₀ and accepts H₁ if C^mdash _n is small. Properties of the two tests are compared based on theoretical results and simulated results.     

Group sequential x2 statistic for testing the difference of two mean vectors in clinical trials

In this study we discuss the group sequential procedures for comparing two treatments based on multivariate observations in clinical trials. Also we suppose that a response vector on each of two treatments has a multivariate normal distribution with unknown covariance matrix. Then we propose a group sequential x² statistic in order to carry out repeated significance test for hypothesis of no difference between two population mean vectors. In order to realize the group sequential test where average sample number is reduced, we propose another modified group sequential x² statistic by extension of Jennison and Turnbull ( 1991 ). After construction of repeated confidence boundaries for making the repeated significance test, we compare two group sequential procedures based on two statistics regarding the average sample number and the power of the test in the simulations.     

A test for gamma DFR alternative

In this article, a test for exponentiality against gamma DFR alternative based on a quadratic form of the logarithmic observations is proposed. The percentage points and the power of the test are computed through Monte-Carlo simulation. The test is seen to perform well as compared to a chi-square test proposed by Bain and Engelhardt(1975).     

P-value adjustment for multiple binary endpoints

The p-value-based adjustment of individual endpoints and the global test for an overall inference are the two general approaches for the analysis of multiple endpoints. Statistical procedures developed for testing multivariate outcomes often assume that the multivariate endpoints are either independent or normally distributed. This paper presents a general approach for the analysis of multivariate binary data under the framework of generalized linear models. The generalized estimating equations (GEE) approach is applied to estimate the correlation matrix of the test statistics using the identity and exchangeable working correlation matrices with the model-based as well as robust estimators. The objectives of the approaches are the adjustment of p-values of individual endpoints to identify the affected endpoints as well as the global test of an overall effect. A Monte Carlo simulation was conducted to evaluate the overall family wise error (FWE) rates of the single-step down p-value adjustment approach from two adjustment methods to three global test statistics. The p-value adjustment approach seems to control the FWE better than the global approach Applications of the proposed methods are illustrated by analyzing a carcinogenicity experiment designed to study the dose response trend for 10 tumor sites, and a developmental toxicity experiment with three malformation types: external, visceral, and skeletal.     

The Relative Size of Windfall Income and the Permanent Income Hypothesis

A reconciliation is offered for the diverse test results on Friedman's permanent income hypothesis. A large data sample of those receiving windfall income in the Bureau of Labor Statistics' 1972–1973 Consumer Expenditure Survey is divided according to the size of the windfall relative to estimated permanent income. A pattern of a declining marginal propensity to consume windfall income as the relative size of the windfall increases is apparent. These results support the permanent income hypothesis for relatively large windfalls.     

Extreme probabilities for contingency tables under row and column independence with application to fisher's exact test

Theorerms are proved for the maxima and minima of IIR_i!/IIC_j!/T!II_yij ! over r× c contingcncy tables Y=(y_ij) with row sums R₁,…,R_r, column sums C₁,…,C_c, and grand total T. These results are imlplemented into the network algorithm of Mehta and Patel (1983) for computing the P-value of Fisher's exact test for unordered r×c contingency tables. The decrease in the amount of computing time can be substantial when the column sums are very different.     

Prediction intervals in exponential families

A method for obtaining prediction intervals for an outcome of a future experiment is presented. The method uses hypothesis testing as a tool to derive prediction intervals and assumes that the probability distributions of informative and future experiments are one parameter exponential families. Asymptotic similar mean coverage prediction intervals are derived using the score test as a test statistics. Examples are presented and asymptotic prediction limits are compared with the prediction limits given in the literature.