医学图像分析技术及其应用的研究

信息图像化是一个受到广泛重视的研究课题,而图像的定量分析关系到图像中所包含的信息能否被很好的提取和利用.本文介绍了图像分析技术的原理及过程,着重介绍了自行研制的图像分析仪的应用实例.     

网络社会公众同情形成过程中的媒介作用机制研究

在网络社会的社会实践过程中,信息传递的充分和对称并没有避免公众同情与事实本身形成偏差的出现。由于信息技术改变了人们的生活方式,传播网络上的发声成为了节点化生活中的人们参与社会事务的主要手段。社会资本运动的核心转变为文化资本,公众同情作为传播过程中核心节点——话题序参量媒体参与社会资本活动的重要工具,在公共舆论事件的发展和演变过程中起着重要的作用。     

复杂岩性地区岩性识别与储层预测

中国陆相地层岩性成分较为复杂,岩性波阻抗值常呈多极分布。水动能强度的急剧变化、高频率的水进水退等沉积背景造成了薄互层广泛发育的特点。储层间干涉现象普遍存在,直接影响到地震岩性解释的精度。针对复杂岩性地区岩性–波阻抗关系复杂的特点,系统分析了造成传统地震储层预测方法解释误差的原因。根据复杂岩性的地球物理响应特点,选取对区分复杂岩性敏感的测井参数。同时,将90° 相位化地震数据作为测井参数反演的相对波阻抗约束数据体。研究结果表明,该方法对复杂岩性进行了有效的区分,达到了精细描述复杂岩性地区储层空间发育及平面展布特点的目的。     

深井水平井水平段水力延伸能力评价与分析

对影响水平井水平段延伸能力的因素进行了分析,然后根据钻井液流体力学理论,建立了水平井循环压耗计算模型,分别对水平井总循环压耗和水平段环空压耗进行计算,进而求出了水平井水平段极限延伸长度值;对钻井液密度、钻井泵额定压力、岩屑床高度和钻井液排量对水平段水力延伸能力的影响进行了分析。研究表明,水平段水力延伸能力受钻井液密度、钻井泵额定压力、岩屑床高度和钻井液排量等多个因素共同影响。为了提高深井水平井的延伸能力,应使用较低密度的钻井液;尽量保持较低的岩屑床高度;钻井液排量应尽量小。同时还认识到,深井水平井水力延伸能力主要受到钻井泵额定压力的制约。研发高额定压力的钻井泵,是提高深井水平井水力延伸能力的主要措施。     

On drift parameter estimation in models with fractional Brownian motion

We consider a stochastic differential equation involving standard and fractional Brownian motion with unknown drift parameter to be estimated. We investigate the standard maximum likelihood estimate of the drift parameter, two non-standard estimates and three estimates for the sequential estimation. Model strong consistency and some other properties are proved. The linear model and Ornstein–Uhlenbeck model are studied in detail. As an auxiliary result, an asymptotic behaviour of the fractional derivative of the fractional Brownian motion is established.     

Threshold‐free estimation of functional antibody titers of a group B streptococcus opsonophagocytic killing assay

Opsonophagocytic killing assays (OPKA) are routinely used for the quantification of bactericidal antibodies in blood serum samples. Quantification of the OPKA readout, the titer, provides the basis for the statistical analysis of vaccine clinical trials having functional immune response endpoints. Traditional OPKA titers are defined as the maximum serum dilution yielding a predefined bacterial killing threshold value, and they are estimated by fitting a dose‐response model to the dilution‐killing curve. This paper illustrates a novel definition of titer, the threshold‐free titer, which preserves biological interpretability while not depending on any killing threshold or on a postulated shape of the dose‐response curve. These titers are shown to be more precise than the traditional threshold‐based titers when using simulated and experimental group B streptococcus OPKA experimental data. Also, titer linearity is shown to be not measurable when using threshold‐based titers, whereas it becomes measurable using threshold‐free titers. The biological interpretability and operational characteristics demonstrated here indicate that threshold‐free titers are an appropriate tool for the routine analysis of OPKA data. Copyright © 2015 John Wiley & Sons, Ltd.     

“三驾马车”与福建经济增长的动态关系——基于时变参数状态空间模型的实证研究

基于福建省地区生产总值、消费、投资和净出口数据,构建了揭示"三驾马车"与福建经济增长间动态关系的变参数状态空间模型,分析了其动态变化的轨迹与趋势。实证结果表明:"三驾马车"对福建经济增长的拉动作用具有明显的阶段性特征,虽然投资的拉动作用一直超过消费和净出口,但2005年后消费的拉动作用在稳步增强而投资的拉动作用在逐年减弱,说明福建经济对投资的依赖性正在下降,经济转型早已开始并且趋势稳定,正在稳步进入可持续的发展轨道,政府无需做过多的干预。     

农村社区建设的参数分析

农村社区建设应坚持科学发展观,按照"生产发展、生活宽裕、乡风文明、村容整洁、管理民主"的社会主义新农村建设目标要求,建设人与自然和谐相处的村民"宜居社区"和"精神家园"。社区建设涵盖经济收入指数、人居环境指数、居民幸福指数、社区参与指数、平安康乐指数、福利保障指数、社区归属感等参数。     

Weighted bivariate logarithmic series distributions

In this paper, we are interested in the weighted distributions of a bivariate three parameter logarithmic series distribution studied by Kocherlakota and Kocherlakota (1990). The weighted versions of the model are derived with weight W(x,y) = x^[r] y^[s]. Explicit expressions for the probability mass function and probability generating functions are derived in the case r = s = l. The marginal and conditional distributions are derived in the general case. The maximum likelihood estimation of the parameters, in both two parameter and three parameter cases, is studied. A procedure for computer generation of bivariate data from a discrete distribution is described. This enables us to present two examples, in order to illustrate the methods developed, for finding the maximum likelihood estimates.     

Smoothing a Time Series by Segments of the Data Range

We consider the problem of estimating a trend with different amounts of smoothness for segments of a time series subjected to different variability regimes. We propose using an unobserved components model to consider the existence of at least two data segments. We first fix some desired percentages of smoothness for the trend segments and deduce the corresponding smoothing parameters involved. Once the size of each segment is chosen, the smoothing formulas here derived produce trend estimates for all segments with the desired smoothness as well as their corresponding estimated variances. Empirical examples from demography and economics illustrate our proposal.