Statistical and Combinatorial Aspects of Comparative Genomics*

Abstract. This document presents a survey of the statistical and combinatorial aspects of four areas of comparative genomics: gene order based measures of evolutionary distances between species, construction of phylogenetic trees, detection of horizontal transfer of genes, and detection of ancient whole genome duplications.     

Assessing goodness-of-fit of categorical regression models based on case-control data

Demonstrated equivalence between a categorical regression model based on case‐control data and an I‐sample semiparametric selection bias model leads to a new goodness‐of‐fit test. The proposed test statistic is an extension of an existing Kolmogorov–Smirnov‐type statistic and is the weighted average of the absolute differences between two estimated distribution functions in each response category. The paper establishes an optimal property for the maximum semiparametric likelihood estimator of the parameters in the I‐sample semiparametric selection bias model. It also presents a bootstrap procedure, some simulation results and an analysis of two real datasets.     

实行毕业设计(论文)网络管理的探索

介绍了一种基于网络的毕业设计(论文)管理系统.通过对毕业设计(论文)管理现状的分析、网络管理策略的介绍和网络管理结果的研究,指出了实行网络管理的可行性和必要性.同时,对如何有效地利用网络管理提高毕业设计(论文)质量提出了几点建议.     

翻译:意识形态的建构、解构、重建与解读

翻译不仅是语言之间信息转换的文化活动,而且是一系列复杂的思维活动。意识形态以不同的语言形式隐藏在语篇之中,以各种隐蔽方式潜移默化地影响着作者写作、译者翻译以及读者解读文本。本文拟以批评语言学为主要方法论,强调翻译中语言分析和社会分析相结合的重要性,同时主张翻译研究应以语篇为单位,特别注意考察作者、译者、读者在翻译过程中的三元关系及其在意识形态的建构、解构、重建和解读过程中的作用,以便弄清翻译的本质并有效地解释那些"不忠"的现象。     

“法律基础”课教学法的改革与实践

在法律基础课教学活动中 ,充分强调学生的主体作用 ,鼓励学生参与到每个教学环节。老师首先指出重点 ,引导阅读 ,然后指导学生讨论、讲解 ,最后总结 ,回答提问。其核心思想是教学活动中师生的“互动” ,提高学生分析问题和解决问题的能力     

谈四六级考试改革后的课堂教学

文章主要从教学内容、教学模式、课时及测评等方面,探讨了四六级考试改革后的一些教学应对措施,以期对今后大学英语教学质量的提高有一定的促进作用。     

Quantifying uncertainty in the biospheric carbon flux for England and Wales

Summary.  A crucial issue in the current global warming debate is the effect of vegetation and soils on carbon dioxide (CO₂) concentrations in the atmosphere. Vegetation can extract CO₂ through photosynthesis, but respiration, decay of soil organic matter and disturbance effects such as fire return it to the atmosphere. The balance of these processes is the net carbon flux. To estimate the biospheric carbon flux for England and Wales, we address the statistical problem of inference for the sum of multiple outputs from a complex deterministic computer code whose input parameters are uncertain. The code is a process model which simulates the carbon dynamics of vegetation and soils, including the amount of carbon that is stored as a result of photosynthesis and the amount that is returned to the atmosphere through respiration. The aggregation of outputs corresponding to multiple sites and types of vegetation in a region gives an estimate of the total carbon flux for that region over a period of time. Expert prior opinions are elicited for marginal uncertainty about the relevant input parameters and for correlations of inputs between sites. A Gaussian process model is used to build emulators of the multiple code outputs and Bayesian uncertainty analysis is then used to propagate uncertainty in the input parameters through to uncertainty on the aggregated output. Numerical results are presented for England and Wales in the year 2000. It is estimated that vegetation and soils in England and Wales constituted a net sink of 7.55 Mt C (1 Mt C = 10¹² g of carbon) in 2000, with standard deviation 0.56 Mt C resulting from the sources of uncertainty that are considered.     

基于核心能力的企业过程再造

阐述了企业过程再造(BPR)和核心能力的内涵及本质,分析了核心过程与核心能力二者之间的关系,指出企业过程再造不能脱离核心能力这一本质,BPR本质上应该是基于核心能力的再造。给出了基于核心能力实施BPR的6个具体步骤:即识别核心能力,识别核心过程,定义经营业绩,找出问题,确定方案和实施方案。     

论美术新课程教学过程的特征

新的《全日制义务教育美术课程标准(实验稿)》,要求美术教育以发展学生的艺术素养、人文素养及促进学生的发展为主要目标。新标准要求下的美术教育与传统美术教育相比,教学过程具有学生中心性、综合性、过程性、实践性、开放性、创造性、师生互动性、美育性、兴趣性和个性性等新的特征。     

Empirical Non-Parametric Control Charts: Estimation Effects and Corrections

Owing to the extreme quantiles involved, standard control charts are very sensitive to the effects of parameter estimation and non-normality. More general parametric charts have been devised to deal with the latter complication and corrections have been derived to compensate for the estimation step, both under normal and parametric models. The resulting procedures offer a satisfactory solution over a broad range of underlying distributions. However, situations do occur where even such a large model is inadequate and nothing remains but to consider non- parametric charts. In principle, these form ideal solutions, but the problem is that huge sample sizes are required for the estimation step. Otherwise the resulting stochastic error is so large that the chart is very unstable, a disadvantage that seems to outweigh the advantage of avoiding the model error from the parametric case. Here we analyse under what conditions non-parametric charts actually become feasible alternatives for their parametric counterparts. In particular, corrected versions are suggested for which a possible change point is reached at sample sizes that are markedly less huge (but still larger than the customary range). These corrections serve to control the behaviour during in-control (markedly wrong outcomes of the estimates only occur sufficiently rarely). The price for this protection will clearly be some loss of detection power during out-of-control. A change point comes in view as soon as this loss can be made sufficiently small.