Construction of orthogonal factorial designs controlling interaction efficiencies

This paper employs some variants of the usual Kronecker product to construct orthogonal factorial designs controlling the interaction efficiencies. The methods suggested have a fairly wide coverage and the resulting designs involve a small number of replicates.     

L1 for the simple linear regression model

By modifying the direct method to solve the overdetermined linear system we are able to present an algorithm for L₁ estimation which appears to be superior computationally to any other known algorithm for the simple linear regression problem.     

Bootstrap method in ranking and slippage problems

In this paper, the bootstrap method of Efron (1979) is given for a ranking and a slippage problem, where the ranking (or slippage) is with respect to the mean of the distributions. The method is also applied to obtain a confidence interval for the largest mean.     

Gibbs sampling for marginal posterior expectations

In earlier work (Gelfand and Smith, 1990 and Gelfand et al, 1990) a sampling based approach using the Gibbs sampler was offered as a means for developing marginal posterior densities for a wide range of Bayesian problems several of which were previously inaccessible. Our purpose here is two-fold. First we flesh out the implementation of this approach for calculation of arbitrary expectations of interest. Secondly we offer comparison with perhaps the most prominent approach for calculating posterior expectations, analytic approximation involving application of the LaPlace method. Several illustrative examples are discussed as well. Clear advantages for the sampling based approach emerge.     

Evaluation of an analysis approach used to account for extra-variation in clustered categorical responses

This article presents the results of a simulation study investigating the performance of an approach developed by Miller and Landis (1991) for the analysis of clustered categorical responses. Evaluation of this “two-step” approach, which utilizes the method of moments to estimate the extra-variation pardmeters and subsequently incorporates these parameters into estimating equations for modelling the marginal expectations, is carried out in an experimental setting involving a comparison between two groups of observations. We assume that data for both groups are collected from each cluster and responses are measured on a three-point ordinal scale. The performance of the estimators used in both “steps” of the analysisis investigated and comparisons are made to an alternative analysismethod that ignores the clustering. The results indicate that in the chosen setting the test for a difference between groups generally operatbs at the nominal α=0.05 for 10 or more clusters and hasincreasing power with both an increasing number of clusters and an inrreasing treatment effect. These results provide a striking contrasc to those obtained from an improper analysis that ignores clustering.     

Estimation of gene/haplotype frequencies in genetic marker systems based on phenotype data

Two equivalent methods (gene counting and maximum likelihood) for estimating gene frequencies in a general genetic marker system based on observed phenotype data are derived. Under the maximum likelihood approach, an expression is given for the estimated covariance matrix from which estimated standard errors of the estimators can be found. In addition, consideration is given to the problem of estimating gene frequencies when there are available several independent population data sets.     

On estimating the dimensionality in discriminant analysis

In discriminant analysis, the dimension of the hyperplane which population mean vectors span is called the dimensionality. The procedures commonly used to estimate this dimension involve testing a sequence of dimensionality hypotheses as well as model fitting approaches based on (consistent) Akaike's method, (modified) Mallows' method and Schwarz's method. The marginal log-likelihood (MLL) method is developed and the asymptotic distribution of the dimensionality estimated by this method for normal populations is derived. Furthermore a modified marginal log-likelihood (MMLL) method is also considered. The MLL method is not consistent for large samples and two modified criteria are proposed which attain asymptotic consistency. Some comments are made with regard to the robustness of this method to departures from normality. The operating characteristics of the various methods proposed are examined and compared.     

Time series count data regression

The count data model studied in the paper extends the Poisson model by al-lowing for overdispersion and serial correlation. Alternative approaches to esti-mate nuisance parameters, required for the correction of the Poisson maximum likelihood covariance matrix estimator and for a quasi-likelihood estimator, are studied. The estimators are evaluated by finite sample Monte Carlo experi-mentation. It is found that the Poisson maximum likelihood estimator with corrected covariance matrix estimators provide reliable inferences for longer time series. Overdispersion test statistics are wellbehaved, while conventional portmanteau statistics for white noise have too large sizes. Two empirical illustrations are included.