连分式算法插值顺序的有效安排

n节连分式算法是一个实用的一维搜索方法。构造连分式插位函数时,部分分母的计算在该算法中占有较大的比重,本文通过对插值点先后顺序的有效安排,使得部分分母的计算量下降近三分之一。最后,对该算法可能遇到的数值困难提供了一个实施方案。     

Conservatism of the Accident Sequence Evaluation Program HRA Procedure

This paper presents a limited assessment of the conservatism of the Accident Sequence Evaluation Program (ASEP) human reliability analysis (HRA) procedure described in NUREG/CR-4772. The data for this study are derived from simulator examination reports from the NRC requalification examination cycle for nuclear power plant operators. The ASEP procedure was used to estimate human error probability (HEP) values for critical tasks, and the HEP results were compared with the failure rates observed in the examinations. The ASEP procedure was applied by PNNL operator license examiners who supplemented the limited information in the examination reports with expert judgment based upon their extensive simulator examination experience. Comparison of the average of the ASEP HEP values with the fraction of the population actually failed and demonstrated that the ASEP HEP values are larger (conservative) by a statistically significant average factor of two. Partitioning of tasks into subgroups based on the ASEP HEP values and comparison of the subgroup average ASEP HEP values with observed subgroup failure rates showed little or no conservatism for small ASEP HEP values, but considerable conservatism for larger ASEP HEP values.     

从12SrRNA部分基因序列探讨鳄的系统发生关系

本文用常规方法测定了雅卡凯门鳄（caiman yacane）、新几内亚鳄（crocodylus novaeguineae）等2种鳄类的约400bp的mtDNA12SrRNA基因片段的部分序列，所测序列与GenBank中的其他18种鳄类的12SrRNA基因相应片段同源序列一起经Clustal X1．8软件进行比对，并以乌龟（chinemys reevesii）为外群，用ClustalX（1．8），Mega2软件以及paup软件将这20种鳄的12SrRNA基因部分序列进行比对后构建了20种鳄的进化关系树，并分别用NJ树，MP树探讨它们之间的系统发生关系。其结果显示：食鱼鳄属Gavialis与马来假食鱼鳄属Tomistoma的亲缘关系较近，构成姐妹群并位于鳄科分支的基部。非洲窄吻鳄（Crocodylus cataphractus）与骨喉鳄（Osteolaemus retraspis）形成姐妹群，它们的亲缘关系比与其它真鳄类的关系更近，赞同非洲窄吻鳄应从鳄属中独土出来归属于长吻鳄属Mecistops的观点，因此鳄科包括鳄属、骨喉鳄属和长吻鳄属，它们的关系为（鳄属（骨喉鳄属，长吻鳄属））。鼍科4属中凯门鳄属与黑鳄属关系最近，接下来的是古鳄属、鼍属，而且鼍属是鼍科中起源最早的类群。扬予鳄（Alligator sinensis）与密河鳄（Alligator mississippiensis）较近的亲缘关系得到支持，但它们并没有形成姐妹群关系。     

Statistical methodology for assessing homology of intronic regions of genes

We consider the problem of statistically evaluating the similarity of DNA intronic regions of genes. Present algorithms are based on matching a sequence of interest with known DNA sequences in a gene bank and are designed primarily to assess homology among exonic regions of genes. Most research focuses on exonic regions because they have a clear biological significance, coding for proteins, and therefore tend to be more conserved in evolution than intronic regions. To investigate whether the intronic features of genes whose expression is highly sensitive to environmental perturbations differ from genes that have a more constant expression, a collection of oncogenes, tumor suppressor genes, and nonregulatory genes involved in energy metabolism are compared. An analysis of the features of these genes' intronic regions result in clustering by regulatory group. In addition, Billingsley's test for Markov structure (1961) suggests that 67% of the intronic regions in this collection of genes show evidence of nonrandom structure, indicating the possibility of a biological function for these regions. The result of Billingsley's test for homology is used as input to a clustering algorithm. The biological significance of this methodology lies in the identification of groups based on the intronic regions from genes of unknown function. With the advent of rapid sequencing techniques, there is a great need for statistical techniques to help identify the purpose of poorly understood portions of genes. These methods can be utilized to assess the functional group to which such a gene might possibly belong.     

直接序列扩频信号PN序列盲估计方法

在非协作信息侦测情况下,提出了一种实用的直接序列扩频(DS-SS)通信信号PN码序列的快速盲估计方法。该方法根据DS-SS基带信号的特点,首先采用二阶循环统计量估计PN码周期,然后利用分段互相关平均估计PN码同步始点;并在准确预估计这2个参数的基础上,将接收信号以PN码周期分成多个时段,利用多重互相关方法估计PN码序列。理论分析与仿真表明,该方法在截获信号信噪比很低的情况下有很好的估计性能,且无需任何先验知识,对PN码码型也没有任何限制,是一种有效的快速盲估计方法。     

无线光通信脉冲位置调制的符号同步技术

讨论了PPM序列的符号同步原理;在分析随机PPM序列的精确符号同步概率上限的基础上,给出了一种在PPM序列中插入同步信号来实现PPM精确符号同步的方案及其数字逻辑电路实现。该方案通过改变PPM调制序列结构,按照一定的间隔在PPM序列中插入脉冲时隙肩并肩的2个相邻符号作为同步符号,通过对同步符号的检测来提取同步信号。理论及仿真实验表明,该方案能实现PPM精确符号同步。     

文变染乎世情兴废系乎时序——《文心雕龙·时序》的文学史论认识

《文心雕龙.时序》的“质文代变”和“文变染乎世情”是刘勰在共时性框架下的对于历代文学的总结,“崇替在选”揭示了政治教化、社会风尚和统治者好恶对于文学的影响,反映出刘勰的文学史的线索观是完全的他律论模式,并以经典作为主要的文学史的价值评判标准。     

用二元n维序列证明一些组合系数恒等式

通过建立“二元集上n维序列”概念,用组合分析的新方法证明了一些组合恒等式.     

Detecting a changed segment in DNA sequences

Non-coding deoxyribonucleic acid (DNA) can typically be modelled by a sequence of Bernoulli random variables by coding one base, e.g. T, as 1 and other bases as 0. If a segment of a sequence is functionally important, the probability of a 1 will be different in this changed segment from that in the surrounding DNA. It is important to be able to see whether such a segment occurs in a particular DNA sequence and to pin-point it so that a molecular biologist can investigate its possible function. Here we discuss methods for testing the occurrence of such a changed segment and how to estimate the end points of it. Maximum-likelihood-based methods are not very tractable and so a nonparametric method based on the approach of Pettitt has been developed. The problem and its solution are illustrated by a specific DNA example.     

陈天然版画艺术论析

从纵向、历时性的艺术转换与横向、版画的美学特质两个视角,论述陈天然感应时代脉搏的艺术道路及体现其个性品格的质朴美、诗境美、书法笔意美三大特征.通过其成长环境、文化之根、智能结构、艺术修养等多侧面,分析其特色形成的基因及成功的经验.