Composite Estimation for Single‐Index Models with Responses Subject to Detection Limits

We propose a semiparametric estimator for single‐index models with censored responses due to detection limits. In the presence of left censoring, the mean function cannot be identified without any parametric distributional assumptions, but the quantile function is still identifiable at upper quantile levels. To avoid parametric distributional assumption, we propose to fit censored quantile regression and combine information across quantile levels to estimate the unknown smooth link function and the index parameter. Under some regularity conditions, we show that the estimated link function achieves the non‐parametric optimal convergence rate, and the estimated index parameter is asymptotically normal. The simulation study shows that the proposed estimator is competitive with the omniscient least squares estimator based on the latent uncensored responses for data with normal errors but much more efficient for heavy‐tailed data under light and moderate censoring. The practical value of the proposed method is demonstrated through the analysis of a human immunodeficiency virus antibody data set.     

Non uniform exponential bounds on normal approximation by Stein’s method and monotone size bias couplings

It is known that the normal approximation is applicable for sums of non negative random variables, W, with the commonly employed couplings. In this work, we use the Stein’s method to obtain a general theorem of non uniform exponential bound on normal approximation base on monotone size bias couplings of W. Applications of the main result to give the bound on normal approximation for binomial random variable, the number of bulbs on at the terminal time in the lightbulb process, and the number of m runs are also provided.     

Estimation of Sobol's sensitivity indices under generalized linear models

We derive explicit formulas for Sobol's sensitivity indices (SSIs) under the generalized linear models (GLMs) with independent or multivariate normal inputs. We argue that the main-effect SSIs provide a powerful tool for variable selection under GLMs with identity links under polynomial regressions. We also show via examples that the SSI-based variable selection results are similar to the ones obtained by the random forest algorithm but without the computational burden of data permutation. Finally, applying our results to the problem of gene network discovery, we identify through the SSI analysis of a public microarray dataset several novel higher-order gene–gene interactions missed out by the more standard inference methods. The relevant functions for SSI analysis derived here under GLMs with identity, log, and logit links are implemented and made available in the R package Sobol sensitivity.     

Independent attributes control chart for Markov-dependent processes

Statistical process monitoring (SPM) is a very efficient tool to maintain and to improve the quality of a product. In many industrial processes, end product has two or more attribute-type quality characteristics. Some of them are independent, but the observations are Markovian dependent. It is essential to develop a control chart for such situations. In this article, we develop an Independent Attributes Control Chart for Markov Dependent Processes based on error probabilities criterion under the assumption of one-step Markov dependency. Implementation of the chart is similar to that of Shewhart-type chart. Performance of the chart has been studied using probability of detecting shift criterion. A procedure to identify the attribute(s) responsible for out-of-control status of the process is given.     

A new extension of the FGM copula for negative association

In this paper we introduced a single parameter, absolutely continuous and radially symmetric bivariate extension of the Farlie-Gumbel-Morgenstern (FGM) family of copulas. Specifically, this extension measures the higher negative dependencies than most FGM extensions available in literature. Closed-form formulas for distribution, quantile, density, conditional distribution, regression, Spearman's rho, Kendall's tau, and Gini's gamma are obtained. In addition, a formula for random variate generations is presented in closed-form to facilitate simulation studies. We conduct both paired and multiple comparisons with Frank, Gaussian, and Plackett copulas to investigate the performance based on Vuong's test. Furthermore, the new copula is compared with Frank, Gaussian, and Plackett copulas using both Kolmogorov-Smirnov and Cramér-von Mises type test statistics. Finally, a bivariate dataset is analyzed to compare and illustrate the flexibility of the new copula for negative dependence.     

Heteroscedastic Global Tests that the Regression Parameters for Two or More Independent Groups are Identical

Simulation results are reported on methods that allow both within group and between group heteroscedasticity when testing the hypothesis that independent groups have identical regression parameters. The methods are based on a combination of extant techniques, but their finite-sample properties have not been studied. Included are results on the impact of removing all leverage points or just bad leverage points. The method used to identify leverage points can be important and can improve control over the Type I error probability. Results are illustrated using data from the Well Elderly II study.     

Shannon Information In k-records

In this article, we present results on the Shannon information (SI) contained in upper(lower) k-record values and associated k-record times. We then establish an interesting relationship between the SI content of a random sample of fixed size, and the SI in the data consisting of sequential maxima. We also consider the information contained in the k-record data from an inverse sampling plan (ISP).     

Improved approaches to interval estimation of effective doses for a logistic dose-response curve

Asymptotic confidence (delta) intervals and intervals based upon the use of Fieller's theorem are alternative methods for constructing intervals for the <$>gamma<$>% effective doses (ED<$>_gamma<$>). Sitter and Wu (1993) provided a comparison of the two approaches for the ED<$>_{50}<$>, for the case in which a logistic dose response curve is assumed. They showed that the Fieller intervals are generally superior. In this paper, we introduce two new families of intervals, both of which include the delta and Fieller intervals as special cases. In addition we consider interval estimation of the ED<$>_{90}<$> as well as the ED<$>_{50}<$>. We provide a comparison of the various methods for the problem of constructing a confidence interval for the ED<$>_gamma<$>.     

The Complete Exact Null Distribution of Spearman's Rho for n = 12(1)18

Spearman's rank correlation coefficient, Rho, is a widely used nonparametric measure of association. Complete, exact tables of the null distribution are calculated and presented for n = 12 to 18.