What to Do at Low Doses: A Bounding Approach for Economic Analysis

To quantify the health benefits of environmental policies, economists generally require estimates of the reduced probability of illness or death. For policies that reduce exposure to carcinogenic substances, these estimates traditionally have been obtained through the linear extrapolation of experimental dose-response data to low-exposure scenarios as described in the U.S. Environmental Protection Agency's Guidelines for Carcinogen Risk Assessment (1986). In response to evolving scientific knowledge, EPA proposed revisions to the guidelines in 1996. Under the proposed revisions, dose-response relationships would not be estimated for carcinogens thought to exhibit nonlinear modes of action. Such a change in cancer-risk assessment methods and outputs will likely have serious consequences for how benefit-cost analyses of policies aimed at reducing cancer risks are conducted. Any tendency for reduced quantification of effects in environmental risk assessments, such as those contemplated in the revisions to EPA's cancer-risk assessment guidelines, impedes the ability of economic analysts to respond to increasing calls for benefit-cost analysis. This article examines the implications for benefit-cost analysis of carcinogenic exposures of the proposed changes to the 1986 Guidelines and proposes an approach for bounding dose-response relationships when no biologically based models are available. In spite of the more limited quantitative information provided in a carcinogen risk assessment under the proposed revisions to the guidelines, we argue that reasonable bounds on dose-response relationships can be estimated for low-level exposures to nonlinear carcinogens. This approach yields estimates of reduced illness for use in a benefit-cost analysis while incorporating evidence of nonlinearities in the dose-response relationship. As an illustration, the bounding approach is applied to the case of chloroform exposure.     

乐教与儒者的宗教情怀

乐教是理解儒家精神不可忽视的重要方面。乐教扎根于“亲亲”之情,具体体现为与“忧患意识”有别,而与“安”“乐”相协调一致的“怛”和“哀”“悲”之情。此情实质上是超越的天道内化为人的心性而落实下来的生命意义与价值得以呈现的方式。儒者虽深知人生之哀、悲,但以乐入手,解悟和转化现实的人生与宇宙,是一大特色。如此,宗教情怀转化为现实的人生关怀,成为特有的礼乐文明的核心内涵。     

飘散在恋恋风尘中的浅吟低唱——侯孝贤和他的《恋恋风尘》

侯孝贤在《恋恋风尘》中使用长镜头、固定镜头表现出特有的电影美学观念 ,他的影片洋溢着抒情诗人的人文关怀 ,传递着中国古典美学的特有神韵。其反叛商业传统的电影叙事语言及方法使侯式纯电影表面看来平淡无奇 ,却有“发纤浓于简古、寄至味于淡泊”之意境     

思想政治教育的文化本性与文化选择

思想政治教育具有其特殊的文化本性。从教育内容上看 ,思想政治教育是一种特殊的文化传播 ;从教育的主客体属性及其运作过程看 ,它主要是文化原理的运作 ,是一个文化过程 ;从其作为社会统治和控制手段看 ,它是一种人文力。这种文化本性要求思想政治教育必须遵循文化的逻辑 ,进行正确的文化选择。一是要弘扬中国传统文化精华 ,抵御西方文化中的消极因素 ,二是要严格按照教育目的进行文化选择 ,三是要提高教育者的文化素质 ,强化文化选择 ,四是要加强亚文化建设 ,引导受教育者的文化选择。这既有助于实现思想政治教育的目的 ,而且达到了文化价值的展现     

Developing a typology of the 'duty to work', as experienced by lay persons with musculoskeletal disorders

Musculoskeletal diagnoses account for the majority of cases of reduced work capacity. This article investigates lay persons' strategies in relation to work and musculoskeletal disorders. Twenty interviews were conducted and analysed using grounded theory. A typology of self-presentations was developed. The interviewees' self-presentations revealed a strong sense of a 'duty to work'. This sense of duty took four different forms, leading us to categorise persons expressing particular forms as workaholics, work manics, workhorses or relaxed workers. Relaxed workers seem to have the best prognosis for recovery as they had a confident self-agency and worked to fulfil their own needs rather than those of others. This was in contrast to work manics, with an uncertain self-agency and driven to work by others' needs. In conclusion, awareness of such linguistic forms as self-attributions and idiomatic phrases provides an opportunity to identify and talk about individual's self-agency and driving forces in the recovery process.     

The Boston Area Diary Study and the Moral Citizenship of Care

This paper describes the theoretical foundations, empirical findings, and practical and philosophical implications of the Boston Area Diary Study (BADS), a study of the caring behavior of 44 participants over one calendar year. In particular, the paper presents an identification theory of care and discusses how it shaped the conceptualization, collection, and analysis of the data in a year-long diary study of daily voluntary assistance. The findings from the BADS (1) theoretically confirm the identification theory of care; (2) methodologically capture how individuals perceive and carry out caring behavior as a unity; and (3rpar; empirically document the existence of a moral citizenship in America that is substantially more vigorous than is implied by the usual indicators of civic and political citizenship.     

Sampling Strategies for Toxic Air Contaminants

Annual concentrations of toxic air contaminants are of primary concern from the perspective of chronic human exposure assessment and risk analysis. Despite recent advances in air quality monitoring technology, resource and technical constraints often impose limitations on the availability of a sufficient number of ambient concentration measurements for performing environmental risk analysis. Therefore, sample size limitations, representativeness of data, and uncertainties in the estimated annual mean concentration must be examined before performing quantitative risk analysis. In this paper, we discuss several factors that need to be considered in designing field-sampling programs for toxic air contaminants and in verifying compliance with environmental regulations. Specifically, we examine the behavior of SO2, TSP, and CO data as surrogates for toxic air contaminants and as examples of point source, area source, and line source-dominated pollutants, respectively, from the standpoint of sampling design. We demonstrate the use of bootstrap resampling method and normal theory in estimating the annual mean concentration and its 95% confidence bounds from limited sampling data, and illustrate the application of operating characteristic (OC) curves to determine optimum sample size and other sampling strategies. We also outline a statistical procedure, based on a one-sided t-test, that utilizes the sampled concentration data for evaluating whether a sampling site is compliance with relevant ambient guideline concentrations for toxic air contaminants.     

领导愿景与企业绩效关系研究

领导者的前瞻性愿景对组织发展具有重要作用。本文用访谈和问卷调查的方法对国有和民营企业的领导愿景与企业经营业绩之间的关系进行了探讨。结果发现,领导愿景及愿景共享等因素对企业绩效具有直接影响作用。研究者在此基础上提出了建立共同愿景以及培养和选拔企业愿景式领导的对策和建议。     

《 转运汉巧遇洞庭红》的商业解读

凌濛初<转运汉巧遇洞庭红>通过对金老汉藏财失财和文若虚随人出海,两次巧遇发财机会陡然暴富故事的描写,反映了明代中叶以后商业发展的具体场景,反映了关于相互需求的贸易原理和资本增殖的思想.通过文若虚形象的塑造,反映了作者经商和为人相统一的思想.从故事可知,明中叶后商业发展已经有了一定的规模和规范,但也还有一些不利于商业贸易更大发展的因素,如储运和金融手段的滞后等.