Additional results for 'Sequential design approaches for bioequivalence studies with crossover designs'

In 2008, this group published a paper on approaches for two‐stage crossover bioequivalence (BE) studies that allowed for the reestimation of the second‐stage sample size based on the variance estimated from the first‐stage results. The sequential methods considered used an assumed GMR of 0.95 as part of the method for determining power and sample size. This note adds results for an assumed GMR = 0.90. Two of the methods recommended for GMR = 0.95 in the earlier paper have some unacceptable increases in Type I error rate when the GMR is changed to 0.90. If a sponsor wants to assume 0.90 for the GMR, Method D is recommended. Copyright © 2011 John Wiley & Sons, Ltd.     

培育长增长级是贵州县区开发的有效途径

贵州的贫困人口众多 ,地区分布广泛 ,返贫率高且时间快 ,原因是多方面的 ,但长期缺乏长增长极的支撑是一个非常重要的因素。科学发掘、培育长增长极对贵州贫困县区的脱贫致富、遏制生态的继续恶化、创造条件走可持续发展之路、推动产业结构的完善升级和经济社会的整体进步具有极其重要的作用。     

"对NPV与IRR指标的重新认识"的再认识

对NPV与IRR指标的认识存在原则性的分歧.本文对杨廷干博士在其博士论文和专著中关于二者之"重新认识"存在的诸多问题进行了深入分析与批评,提出新的观点和再认识.     

重庆市下岗职工再就业培训问题探究

虽然重庆市政府对下岗职工的再就业问题作了很大的努力和投入 ,但还是有相当一部分下岗职工不能再就业或再就业困难 ,其现状和存在的问题不容乐观。为了有效地解决这一问题 ,必须站在劳动力市场就业的角度来对下岗职工的再就业培训问题作比较深入的探讨 ,以找到一条行之有效的途径 ,大幅度地提高下岗职工的再就业率 ,这对于维护社会稳定 ,促进社会发展 ,保证改革开放的顺利进行具有十分重要的现实意义     

刘勰为什么肯定“般若绝境”

刘勰所用之“般若”虽来自印度佛教逻辑,但从《文心雕龙》篇章中内容上看,却与佛教没多大关系。刘勰是从其哲学本体上肯定般若学在对待“有”、“无”关系上的基本态度的。刘勰的哲学受魏晋玄学尤其是王弼的观点的影响,认为“无”是哲学之本体,但亦不完全否认“有”的存在与价值。王弼主张以有训无、举本统末,与王衍、何晏为首的贵无派完全否认“有”的存在与价值和以裴■、郭象为首的崇有派完全否认“无”的本体意义的观点都不同。而般若学所谓六家七宗等各派,虽观点有分歧,但在对本末有无问题上却基本一致,他们都不像何晏与裴■那样偏执一端,完全否认“有”或完全否认“无”,而是如王弼那样,既肯定“无”为根本,也不否认“有”的存在与价值,这正是《文心雕龙·原道》中所表现出来的刘勰的总的哲学观点,所以他才肯定“般若之绝境”,而不是团于宗教门户之见。     

当代韩国大众文化的发展

大众文化是目前走向现代化国家的最为普遍的 文化消费方式。韩国作为东亚新兴的现代化国家，近年来大众文化获得了长足的发展， 甚至对于周边国家(如中国)产生了很大的影响。本文从历史视角，对韩国大众文化的成 长环境、发展脉络和主要表现形式做了系统考察。     

煤炭城市特殊就业再就业体系的探索

煤炭城市就业再就业是振兴东北老工业基地、实现资源型城市发展接续产业战略亟待解决的问题。这一突出的矛盾有其历史因素,存在着固有的特殊性。因此,在振兴东北老工业基地战略中,国家应考虑制定特殊的政策和采取特殊的措施来解决煤炭城市的就业再就业难题。     

我国小额贷款公司“双赢”机理研究

分析了小额贷款公司的性质没有阻碍反而促进了小额贷款公司发展并达到"双赢"的原因,并对小额贷款公司再融资的潜在风险,以及市场上出现的再融资方式,如小额再贷款公司的建立进行了研究。中国经济发展的不平衡性,信贷资金供需缺口的普遍存在,传统金融机构的低效率以及中国微型金融市场的扭曲是小额贷款公司"双赢"的条件。只要小额贷款公司保持"只贷不存"等性质并在合理考虑成本和利润的前提下提供短期小额贷款,就能实现"双赢"。并运用网络模型研究认为,小额再贷款公司在短期能缓解小额贷款公司后续资金不足的问题,但无法长期解决此问题。     

城镇弱势群体的救助与再就业扶持

本文分析了我国经济转型期城镇弱势群体的形成机理和构成 ,提出了社会救助和再就业并重的扶持战略 ,给出了相应的对策措施     

First Nations parenting and child reunification: Identifying strengths,barriers, and community needs within the child welfare system

First Nations communities are seeking to improve current service delivery models and create alternative evidence‐based strategies. A First Nations child welfare organization has prioritized further understanding of reunification and parenting, including identification of successes and barriers to reunification, and service needs within communities. These priorities were addressed with a community‐based participatory research model and guided by a Research Advisory. Results were analysed using a blend of grounded theory and thematic analysis techniques. Participants indicated that placing children with extended family or within home communities facilitate best child outcomes. These reunifications could be increased by promoting parental and community capacity. Successes identified within communities included available supports, such as those that increased empowerment and community capacity. Identified barriers within communities were the lack of culturally appropriate services, hesitancy to obtain available support due to fears of child welfare intervention, and mental health difficulties of community member.