Anticipated Ethics and Regulatory Challenges in PCORnet: The National Patient-Centered Clinical Research Network

PCORnet, the National Patient-Centered Clinical Research Network, seeks to establish a robust national health data network for patient-centered comparative effectiveness research. This article reports the results of a PCORnet survey designed to identify the ethics and regulatory challenges anticipated in network implementation. A 12-item online survey was developed by leadership of the PCORnet Ethics and Regulatory Task Force; responses were collected from the 29 PCORnet networks. The most pressing ethics issues identified related to informed consent, patient engagement, privacy and confidentiality, and data sharing. High priority regulatory issues included IRB coordination, privacy and confidentiality, informed consent, and data sharing. Over 150 IRBs and five different approaches to managing multisite IRB review were identified within PCORnet. Further empirical and scholarly work, as well as practical and policy guidance, is essential if important initiatives that rely on comparative effectiveness research are to move forward.     

幼儿园实际教育成本的模型构建与核算——以佛山某幼儿园为例

在界定幼儿园实际教育成本含义的基础上，确认其成本项目包含人员支出、公用支出、固定资产折旧和土地使用成本，以此为基础构建了幼儿园实际教育成本计量模型，并以佛山市某幼儿园为例核算出该幼儿园的实际教育成本。通过该园实际教育成本与标准教育成本的比较，发现该幼儿园教育经费投入不足且投入结构不合理，将来应重点增加人员投入。     

The cost‐effectiveness of UK parenting programmes for preventing children's behaviour problems – a review of the evidence

Parenting programmes are widely used in the UK, promoted in policy documents as a cost‐effective way for children's services to address behaviour problems and thereby the longer‐term costs associated with conduct disorders, particularly antisocial behaviour and criminality. To explore whether these programmes are a cost‐effective component of family intervention, this paper examines evidence from cost‐effectiveness studies based on randomized controlled trials, modelling studies estimating longer‐term costs and outcomes, and studies estimating costs of UK parenting programmes, including evidence from routine practice. Findings indicate that parenting programmes have the potential to be cost‐saving in the long term; however, gaps in the evidence include: lack of follow‐up of families who drop out of programmes, absence of control groups in longer‐term follow‐ups, and little information about costs and effects of programmes in routine practice. The size of savings resulting from implementation of effective parenting programmes will depend on the extent to which families likely to be most costly to society attend and experience lasting benefit.     

Mean shift and influence measures in linear measurement error models with stochastic linear restrictions

We present influence diagnostics for linear measurement error models with stochastic linear restrictions using the corrected likelihood of Nakamura in 1990. The case deletion and mean shift outlier models are developed to identify outlying and influential observations. We derive a corrected score test statistic for outlier detection based on mean shift outlier models. The analogs of Cook's distance and likelihood distance are proposed to determine influential observations based on case deletion models. A parametric bootstrap procedure is used to obtain empirical distributions of the test statistics and a simulation study has been used to evaluate the performance of the proposed estimators based on the mean squares error criterion and the score test statistic. Finally, a numerical example is given to illustrate the theoretical results.     

What can we learn from twin studies? A comprehensive evaluation of the equal environments assumption

Twin studies are a major source of information about genetic effects on behavior, but they depend on a controversial assumption known as the equal environments assumption (EEA): that similarity in co-twins’ environments is not predictive of similarity in co-twin outcomes. Although evidence has largely supported the EEA, critics have claimed that environmental similarity has not been measured well, and most studies of the EEA have focused on outcomes related to health and psychology. This article addresses these limitations through (1) a reanalysis of data from the most cited study of the EEA, Loehlin and Nichols (1976), using better measures, and through (2) an analysis of nationally representative twin data from MIDUS using more comprehensive controls on a wider variety of outcomes than previous studies. Results support a middle ground position; it is likely that the EEA is not strictly valid for most outcomes, but the resulting bias is likely modest.     

论我国国外马克思主义研究的三个核心问题——兼论我国国外马克思主义研究的自我身份认同

研究边界的日益模糊、研究对象选择的随意性和研究方法的非历史性,是制约我国国外马克思主义研究进一步走向深入的三大核心问题。应当对国外马克思主义研究的边界和理论性质作大致明确的规定,并且立足于推进中国马克思主义理论建设和现代化实践这一目的出发,破除形而上学的两极思维方式,展开对国外马克思主义理论的研究,实现国外马克思主义研究在当代中国的价值。     

Effective eProcurement implementation process

As eProcurement is gaining popularity in business practice, researchers as well as practitioners have addressed the need of defining a proper eProcurement implementation strategy. This article aims to build an eProcurement implementation framework, which considers the main variables that have an impact on the eProcurement success and the links among them. The goal is to identify the main decisions that companies should take during the three principal phases of the eProcurement adoption (pre-implementation; implementation and post-implementation). Six case studies at different levels of eProcurement adoption have been used to identify the peculiarities of each phase of the process and to provide contingent guidelines.     

Marginal homogeneity,symmetry, and independence

A contingency table of the mc form provides a convenient summary of data when c individuals in a matched set9 each belonging to a different one of c classifications, are identified as belonging to one of m categories, A study in which matched sets (c=3) of 1 case, 1 hospital control, and 1 neighborhood control are classified into one of m=4 occupational categories would be an example, Independence in the cxm tables for each of the matched sets implies symmetry in the summary mc table with consequent marginal homogeneity. Adaptation of the Mantel-Haenszel procedure for testing independence to the case of many cxm tables so as to yield a chi square with (cl)(ml) degrees of freedom (DF) provides a test of marginal homogeneity in the summary mc table. This can be viewed as a test of symmetry directed against alternatives which would make for marginal inhomogeneity and can differ     

The recruitment and selection of hospital medical consultants

Abstract

The literature on selection has been dominated in recent decades by the ‘prediction’ paradigm. Such an approach requires a substantial number of positions to be filled in order to compute validity coefficients. There are other approaches, using a different paradigm, when concentrated on adjusting the organization and the employee. Here careful analysis of job demands is essential. This article describes such an analysis, taking the medical consultant as an example. The method can be used in an iterative way. It is useful when one has to work with small numbers of positions.     

民族社会学视野下的回族女性研究

回族女性研究是中国妇女研究的重要组成部分,20世纪90年代以来,中国回族女性研究取得了长足的进步和发展。本文着力于回顾既往回族女性研究中所涉及的诸多问题展开历史追溯与反思,就回族女性研究的内涵、研究的对象与范围、研究的意义与作用、研究的方法、理论构建、学术素养等学术界较为关注的几个问题进行了论述,在追溯中反思我们今后研究的拓展方向,力求为未来回族女性的发展提供一定参考。