Generalizing the standardized hazard ratio to multivariate proportional hazards regression,with an application to clinical~genomic studies

The standardized hazard ratio for univariate proportional hazards regression is generalized as a scalar to multivariate proportional hazards regression. Estimators of the standardized log hazard ratio are developed, with corrections for bias and for regression to the mean in high-dimensional analyses. Tests of point and interval null hypotheses and confidence intervals are constructed. Cohort sampling study designs, commonly used in prospective–retrospective clinical genomic studies, are accommodated.     

校企合作构建第二课堂的实施效果分析及评价——基于圣奥班(家具设计专业)毕业生跟踪问卷的调查

南京林业大学与浙江圣奥(木业)集团联合创建的“圣奥班”是校企合作联合培养创新型家具设计工程专业人才的成功平台之一.基于圣奥班毕业生的问卷调查,对学生进班动机与目标定位、比较优势、获得的帮助、专业能力提升,以及今后办班建议等方面内容进行了分析.统计结果表明,学校和企业共同搭建的圣奥班平台对学生创新意识,专业能力、就业竞争力等诸多方面都有显著的提升.     

小学校长服务型领导对教师知识分享行为的影响研究

以山东省248名小学教师为有效样本，探讨了服务型领导、教师同事信任、情感承诺和教师知识分享行为之间的关系。研究结果显示：服务型领导与教师知识分享行为显著相关；教师同事信任部分居间联系了服务型领导与知识分享行为之间的关系；教师同事信任部分居间联系了服务型领导与情感承诺之间的关系；情感承诺对服务型领导与知识分享行为关系的中介作用不显著。     

Is prenatal sex selection associated with lower female child mortality?

I examine whether prenatal sex selection has substituted postnatal excess female mortality by analysing the dynamics of child sex ratios between 1980 and 2015 using country-level life table data. I decompose changes in child sex ratios into a ‘fertility’ component attributable to prenatal sex selection and a ‘mortality’ component attributable to sex differentials in postnatal survival. Although reductions in numbers of excess female deaths have accompanied increases in missing female births in all countries experiencing the emergence of prenatal sex selection, relative excess female mortality has persisted in some countries but not others. In South Korea, Armenia, and Azerbaijan, mortality reductions favouring girls accompanied increases in prenatal sex selection. In India, excess female mortality was much higher and largely stable as prenatal sex selection emerged, but slight reductions were seen in the 2000s. In China, although absolute measures showed reductions, relative excess female mortality persisted as prenatal sex selection increased.     

Early stopping in seamless phase I/II clinical trials

In recent years, seamless phase I/II clinical trials have drawn much attention, as they consider both toxicity and efficacy endpoints in finding an optimal dose (OD). Engaging an appropriate number of patients in a trial is a challenging task. This paper attempts a dynamic stopping rule to save resources in phase I/II trials. That is, the stopping rule aims to save patients from unnecessary toxic or subtherapeutic doses. We allow a trial to stop early when widths of the confidence intervals for the dose-response parameters become narrower or when the sample size is equal to a predefined size, whichever comes first. The simulation study of dose-response scenarios in various settings demonstrates that the proposed stopping rule can engage an appropriate number of patients. Therefore, we suggest its use in clinical trials.     

A new confidence interval in errors-in-variables model with known error variance

This paper considers constructing a new confidence interval for the slope parameter in the structural errors-in-variables model with known error variance associated with the regressors. Existing confidence intervals are so severely affected by Gleser–Hwang effect that they are subject to have poor empirical coverage probabilities and unsatisfactory lengths. Moreover, these problems get worse with decreasing reliability ratio which also result in more frequent absence of some existing intervals. To ease these issues, this paper presents a fiducial generalized confidence interval which maintains the correct asymptotic coverage. Simulation results show that this fiducial interval is slightly conservative while often having average length comparable or shorter than the other methods. Finally, we illustrate these confidence intervals with two real data examples, and in the second example some existing intervals do not exist.     

Hypothesis Testing in a Rayleigh Diffusion Model

Applying the large and moderate deviations for the log-likelihood ratio of the Rayleigh diffusion model, we give the negative regions in testing Rayleigh diffusion model and obtain the decay rates of the error probabilities.     

Tail Behavior and Limit Distribution of Maximum of Logarithmic General Error Distribution

Logarithmic general error distribution, an extension of the log-normal distribution, is proposed. Some interesting properties of the log GED are derived. These properties are applied to establish the asymptotic behavior of the ratio of probability densities and the ratio of the tails of the logarithmic general error and log-normal distributions, and to derive the asymptotic distribution of the partial maximum of an independent and identically distributed sequence obeying the log GED.     

探析“隧道效应”在社会治理中的应用

当前在我国经济社会发展不平衡的背景下,社会治理已经并将长期面临新的形势和新的挑战。在这些挑战和问题面前,我们如何通过对我国社会治理状况的深入分析,深化对社会管理规律和特点的认识,不断地进行理论创新,找到建设中国特色社会治理体系应遵循的基本原则,探索适合我国国情的社会治理体制机制,提高社会治理的能力和水平。本文从一个经济学的概念——"隧道效应"出发,将其引入到社会治理的研究中来,分析"隧道效应"发生背后的文化逻辑,并从社会的角度来分析这种正的隧道效应是否可以持续及其政策建议。     

Effects of the social dominance orientation on environmental attitudes of Chilean university students / Efectos de la orientación a la dominancia social sobre las actitudes ambientales de universitarios chilenos

By adopting a multidimensional approach to environmental attitudes (apathy, anthropocentrism, connectedness and emotional affinity with nature), this study explores the relationships between these dimensions, social dominance orientation (SDO) and political orientation. Two hundred and sixty-two Chilean university students filled out an ad hoc online questionnaire. Two confirmatory factorial analyses showed the four typologies of environmental attitudes and the two factors for SDO, which are labelled group dominance and opposition to equality. Through hierarchical regressions, group dominance showed higher explanatory power of environmental attitudes than political orientation. Furthermore, using the bootstrap procedure we showed that group dominance mediated between political orientation and attitudes of apathy, anthropocentrism and connectedness, while opposition to equality mediated between apathy and emotional affinity. We conclude that SDO is an important variable for measuring political ideology while also providing new nuances when analysing the relationships with environmental attitudes.