社会1作介入生态文明建设的可行性分析

改革开放以来,虽然我国经济发展速度比较快,目前国民经济总量跃居世界第二,但代价也比较沉重,其中之一就是生态环境破坏严重。目前,市场与政府在治理生态环境中各有不足,相应会出现市场失灵与政府失灵,而社会工作介入生态环境治理具有自身独特的优势,可以有效弥补二者的缺陷。目前,我国社会工作介入生态文明建设工作既有成功案例,又面临工作者短缺、经费不足、群众认同度低等问题。解决这些问题,需从政府、社区、企业着手分别建立宏观、中观、微观支持,采取个案工作与小组工作的介入模式,社会工作者也要提升自身介入能力,以促进我国经济、社会、环境的协调发展与可持续发展。     

Sexual Dysfunction among Male Patients with Tramadol abuse: A Case-Control Study

Objective: Here we have investigated the association between tramadol abuse and male sexual function. Methods: Eighty-two male tramadol abuse patients and 55 healthy controls (20- to 45-years-old) were included in the study. Data from a sociodemographic questionnaire and the International Index of Erectile Function Questionnaire were collected and analyzed. Results: The tramadol abuse patients were 5 times more likely than their healthy counterparts to have erectile dysfunction. The tramadol abuse patients also had worse scores in the orgasmic, sexual desire, intercourse satisfaction, and overall satisfaction domains compared to the controls. Conclusion: Sexual dysfunctions are common among tramadol abuse patients.     

世界视野中的求子习俗

求子习俗在世界上很普遍,可以分为四种类型。妇女们用求子习俗来否定现实生活中成年男子的生殖能力,但多生多育又是男子们创造能力的最基本的表现形式。子女是多种观念的象征,也是人们延续家族和个人历史的重要手段。     

Do women of reproductive age presenting with pelvic floor dysfunction have undisclosed anal incontinence: A retrospective cohort study

BackgroundIndirect and direct trauma following vaginal birth can negatively impact on the pelvic floor function increasing the risk of anal incontinence. It is often difficult for women to openly disclose that they have anal incontinence and there are limited data collection tools available for the identification of these women in a clinical setting.AimThis study aims to describe the prevalence of undisclosed anal incontinence in antenatal and postnatal women with pelvic floor dysfunction.MethodsRetrospective cohort study of 230 antenatal and postnatal women referred to a Continence Nursing Service in a large tertiary hospital in South Australia, Australia, with pelvic floor dysfunction. A criteria list was utilised to access the primary reason for referral, anal incontinence assessments and attendance to an appointment.ResultsAnal incontinence was identified in 26% of women (n = 59). Anal incontinence was the primary reason for referral amongst 8 women, with the remaining 51 women identified as having anal incontinence following clinical screening via phone consultation. Eighty six percent of women stated they had not previously disclosed anal incontinence to health professionals. Overall, 71% of symptomatic women (n = 28 antenatal and n = 14 postnatal women) attended appointments to a service specialising in pelvic floor dysfunction.ConclusionWomen presenting with urinary incontinence or other markers of pelvic floor dysfunction should be actively screened for anal incontinence as the prevalence of this condition is high amongst childbearing women.     

The Relationship Between Childhood Sexual Abuse and Sexual Dysfunction in Jamaican Adults

This study examined the associations between early traumatic sexualization and later sexual dysfunction in a sample of 100 Jamaican adults while identifying the linkages between age, frequency of abuse, and gender on sexual functioning. Participants were selected via purposive and convenience sampling and divided equally into comparison and experimental groups based on sociodemographic characteristics. Results indicated that childhood sexual abuse is a likely factor in the development of sexual dysfunction in Jamaican adults, especially in the domains of Orgasm and Sexual Drive and Relationship. Gender, frequency, and age of abuse are also seen to impact specific areas of an individual's sexual functioning. Results are discussed in light of previous research for their implications in order to better understand sexuality in the Jamaican context.     

From the enclave to hierarchy – and on to tyranny: the micro‐political organisation of a consultant’s group

No question now, what had happened to the faces of the pigs. The creatures outside looked from pig to man, and from man to pig, and from pig to man again; but already it was impossible to say which was which.

George Orwell, the concluding lines of Animal farm.     

Circadian rhythm of hot flashes and activity levels among prostate cancer patients on androgen deprivation therapy

Abstract

Background: Modifiable risk factors contribute to the pathogenesis of cardiovascular disease (CVD) and erectile dysfunction (ED). We aimed to compare the knowledge about the contribution of modifiable risk factors to the pathogenesis of CVD and ED. The impact of patients’ having modifiable risk factors on the awareness of their negative influence on the development of CVD and ED was examined.

Methods: To this multicenter cohort study, we included 417 patients with CHD who had been hospitalized in the cardiology or cardiac surgery department during the previous six weeks and underwent cardiac rehabilitation in one of the five centers. Knowledge about modifiable risk factors was collected. ED was assessed by an abridged IIEF-5 questionnaire. Comparisons between groups were conducted using the Student’s t-test, Mann–Whitney U test, and Kruskal–Wallis test. Relationships were analyzed with Spearman's rank correlation coefficient.

Results: The mean number of correctly identified risk factors for CVD was significantly higher than those for ED (3.71?±?1.87 vs. 2.00?±?1.94; p?<?.0001). Smoking was the most recognized risk factor both for CVD and ED. Dyslipidemia was least frequently identified as a risk factor for CVD. Sedentary lifestyle was the only risk factor whose incidence did not affect the level of patient knowledge.

Conclusions: Cardiac patients with ED know more about risk factors for CVD than ED. It is necessary to include information about the negative impact of modifiable risk factors on sexual health into education programs promoting healthy lifestyles in men with cardiovascular diseases.     

Endogenous hydrogen sulfide insufficiency as a predictor of sexual dysfunction in aging rats

Objective: Our earlier studies showed that endogenous hydrogen sulfide (H₂S) pathway contributed significantly to erectile function. In this study, we tested the hypothesis that age-dependent changes in the bioavailability of H₂S increased the risk of erectile dysfunction (ED). Methods: Young, adult (3-month) and older (18-month) male Sprague-Dawley rats (n?=?6?8/group) were treated daily with sodium hydrosulfide hydrate (NaHS), DL-propargylglycine, sildenafil or l-NAME for 10 weeks. Subsequent to cavernous nerve electrical stimulation, intracavernosal pressure (ICP) responses were determined, and the samples were collected and processed for hormonal (plasma) and gaseous parameters (plasma and erectile corpus cavernosum [CC]) using standard assay protocols. Results: Aging significantly reduced the ICP response (35.9?±?2.0 mmHg vs. 45.2?±?1.9 mmHg in young controls), which was countered by NaHS (53.5?±?6.0) or sildenafil (52.8?±?9.8) treatment. In these rats, marked increments to testosterone (T) or estradiol resulted from NaHS supplementation. Similar to age-dependent decline in NO, the plasma and CC level of H₂S was significantly lower in senescent rats when compared with young animals (p?<?0.05). Conclusion: Our results confirm that ED with aging may be linked to a derangement in the H₂S pathway accompanied by low T levels. It is likely that a pharmacologic intervention delivering H₂S will provide additional benefits to sexual function from an improved T milieu.     

Testosterone deficiency in male heart failure patients and its effect on endothelial progenitor cells

Background: Endothelial progenitor cells (EPCs) are thought to contribute to reendothelialization and neoangiogenesis. Since it is known that EPCs express a testosterone receptor, we wanted to assess the prevalence of testosterone deficiency in patients with CHF and its impact on circulating EPCs. Methods: 137 male patients with chronic heart failure (CHF) were included (age 61?±?13 years; BMI 29?±?5?kg/m²; New York Heart Association classification (NYHA) I: n = 47, NYHA II: n = 51, NYHA III: n = 39). Numbers of different populations of circulating EPCs were quantified using flow cytometry. Levels of free testosterone and EPC-regulating cytokines were determined using ELISA. Results: The prevalence of testosterone deficiency in our University CHF clinic was 39%. However, there was no difference between patients with and without testosterone deficiency regarding their levels of EPCs. Testosterone levels were inversely correlated with age (R² = ?0.32, p = 0.001) and NYHA status (R² = 0.28, p = 0.001) and correlated with cardiorespiratory capacity (R² = 0.26, p = 0.03). Conclusion: Testosterone deficiency is frequent in male patients with CHF but does not appear to impact the regenerative EPCs.     

Sildenafil: two decades of benefits or risks?

Abstract

Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE-5). A patent was registered for this drug in 1990, which expired in 2010. Since expiration, the drug has been marketed under various trade names or as generic drugs. Numerous clinical trials have been conducted addressing the effectiveness of the drug for erectile dysfunction (ED) and its safety regarding the presence or absence of specific comorbidities. After over 20 years in the market, we need to ask: has the scientific community reached a general consensus as to the overall efficacy and safety of the drug? Can we firmly state that the benefits of the drug outweigh its risks? This review suggests that sildenafil is an effective and easily manageable treatment for erectile dysfunction, both in the absence and in the presence of comorbidities. After two decades of the emergence of sildenafil as a drug of choice for the treatment of ED (and the numerous studies and clinical trials undertaken during this time span), it is now possible to state that the benefits of the drug do outweigh the risks, and represent an significant improvement in the quality of life in men with ED.