Influence diagnostics and outlier tests for semiparametric mixed models

Summary. Semiparametric mixed models are useful in biometric and econometric applications, especially for longitudinal data. Maximum penalized likelihood estimators (MPLEs) have been shown to work well by Zhang and co-workers for both linear coefficients and nonparametric functions. This paper considers the role of influence diagnostics in the MPLE by extending the case deletion and subject deletion analysis of linear models to accommodate the inclusion of a nonparametric component. We focus on influence measures for the fixed effects and provide formulae that are analogous to those for simpler models and readily computable with the MPLE algorithm. We also establish an equivalence between the case or subject deletion model and a mean shift outlier model from which we derive tests for outliers. The influence diagnostics proposed are illustrated through a longitudinal hormone study on progesterone and a simulated example.     

Human Salmonellosis: Estimation of Dose-Illness from Outbreak Data

The quantification of the relationship between the amount of microbial organisms ingested and a specific outcome such as infection, illness, or mortality is a key aspect of quantitative risk assessment. A main problem in determining such dose-response models is the availability of appropriate data. Human feeding trials have been criticized because only young healthy volunteers are selected to participate and low doses, as often occurring in real life, are typically not considered. Epidemiological outbreak data are considered to be more valuable, but are more subject to data uncertainty. In this article, we model the dose-illness relationship based on data of 20 Salmonella outbreaks, as discussed by the World Health Organization. In particular, we model the dose-illness relationship using generalized linear mixed models and fractional polynomials of dose. The fractional polynomial models are modified to satisfy the properties of different types of dose-illness models as proposed by Teunis et al . Within these models, differences in host susceptibility (susceptible versus normal population) are modeled as fixed effects whereas differences in serovar type and food matrix are modeled as random effects. In addition, two bootstrap procedures are presented. A first procedure accounts for stochastic variability whereas a second procedure accounts for both stochastic variability and data uncertainty. The analyses indicate that the susceptible population has a higher probability of illness at low dose levels when the combination pathogen-food matrix is extremely virulent and at high dose levels when the combination is less virulent. Furthermore, the analyses suggest that immunity exists in the normal population but not in the susceptible population.     

A longitudinal study of burnout: the relative importance of dispositions and experiences

This study investigated the relative contribution of personality vs. environmental factors to the genesis of the burnout syndrome. A sample of 221 nursing students in Hamburg, Germany, were administered a battery of personality measures prior to any training. They were later asked to rate various stressors encountered during their practical training on hospital wards and also in nursing school, general aspects of ward climate, the frequency of private life events, and their own well-being on standard measures of burnout. Data were collected at seven time points over a period of 3 years, including the initial assessment (T1-T7). Only complete data sets (N = 123) were used for the analyses. Burnout scores from T2 to T7 were predicted, on the one hand, by the 36 'dispositional' scales of the initial battery and, on the other hand, by a set of 18 'experience-oriented' scales from the later questionnaire's concurrent administration. Scales reflecting well-being were predicted better by experiences than by dispositions. With scales reflecting attitudes towards oneself and patients, respectively, it was the other way around. Thus, both dispositional and experiential views of burnout receive some support here. Intraindividual change in burnout scores could not be linked to dispositional or experiential variables.     

基于虚拟仪器的土壤水分测试系统开发

采用PCl-812PG数据采集卡,基于虚拟仪器技术,以Delphi作为平台开发了土壤含水量测试系统,对AZS -2土壤水分传感器的功能进行了扩展。标定结果及实际应用表明,此系统性能稳定,精度较高。     

转型期中国农村区域消费水平与结构的实证分析

农村消费市场低迷是制约我国经济发展的主要因素。运用主成分聚类方法及Panel Data数据模型,结合1994—2003年的时序截面数据,对我国农村区域消费水平与结构的差异进行静态与动态分析。     

利用数控增益放大器提高A/D转换器的分辨率

文章介绍利用数控增益放大器LH0086大幅度提高A／D转换器分辨率的方法,可将8位A／D转换器的分辨率提高到接近16位A／D的水平,适用于高速数据系采集系统,给出了相应的硬件原理图和软件框图。     

Data relaying with constraints in hierarchical sensor networks

In this paper we present and discuss several optimisation problems that arise in the management of data flow in wireless sensor networks (WSNets). We consider a hierarchical architecture for WSNets composed of sensors, relays, and relay gateways. Sensors send data they generate at a known average bit rate to relays in one hop. The relay nodes use a multi-hop mechanism to reach a set of assigned gateways which then forward the data directly to the base station. We are concerned with finding an assignment of relay gateways to relays so that certain constraints are satisfied. We define a unified model in which constraints such as lifetime, data delay, and data flow splitting are formulated in terms of four optimisation problem in graphs.     

Assessment of modeling longitudinal binary data based on graphical methods

Longitudinal categorical data are commonly applied in a variety of fields and are frequently analyzed by generalized estimating equation (GEE) method. Prior to making further inference based on the GEE model, the assessment of model fit is crucial. Graphical techniques have long been in widespread use for assessing the model adequacy. We develop alternative graphical approaches utilizing plots of marginal model-checking condition and local mean deviance to assess the GEE model with logit link for longitudinal binary responses. The applications of the proposed procedures are illustrated through two longitudinal binary datasets.     

Analytic strategies for longitudinal networks with missing data

Missing data are often problematic when analyzing complete longitudinal social network data. We review approaches for accommodating missing data when analyzing longitudinal network data with stochastic actor-based models. One common practice is to restrict analyses to participants observed at most or all time points, to achieve model convergence. We propose and evaluate an alternative, more inclusive approach to sub-setting and analyzing longitudinal network data, using data from a school friendship network observed at four waves (N = 694). Compared to standard practices, our approach retained more information from partially observed participants, generated a more representative analytic sample, and led to less biased model estimates for this case study. The implications and potential applications for longitudinal network analysis are discussed.     

Substance use disorders and referral to treatment in substantiated cases of child maltreatment

Parents with substance use disorders (SUD) require treatment and support in order to provide children with appropriate care and protection. Using the 2012 National Child Abuse and Neglect Data System (NCANDS), this paper analysed 464 313 substantiated child maltreatment reports to determine (i) the proportion and characteristics of reports involving substance abuse; and (ii) the child and caregiver/perpetrator (C/P) characteristics that predicted referral to treatment as recorded in service plans. Findings indicate that 12% (N = 53 234) of maltreatment reports involved C/P SUD. Yet, of those reports, only (19%) (N = 10 088) were referred to substance abuse treatment as part of their service plan, indicating a large gap between those who need treatment and those who receive it. This finding is important given that parental SUD is consistently linked to poorer child outcomes. Amongst other variables, reports indicate that C/P with co‐occurring emotional disturbance were three times more likely to be referred to treatment for SUD as part of service plans. Additional research is needed regarding the characteristics that distinguish C/P who receive referrals for SUD treatment in substantiated cases of child maltreatment.