D-optimal block designs with at most six varieties

For given positive integers v, b, and k (all of them ≥2) a block design is a k × b array of the variety labels 1,…,v with blocks as columns. For the usual one-way heterogeneity model in standard form the problem is studied of finding a D-optimal block design for estimating the variety contrasts, when no balanced block design (BBD) exists. The paper presents solutions to this problem for v≤6. The results on D-optimality are derived from a graph-theoretic context. Block designs can be considered as multigraphs, and a block design is D-optimal iff its multigraph has greatest complexity (=number of spanning trees).     

Numerical estimation of a probability measure

An iterative solution to the problem of maximizing a concave functional ø defined on the set of all probability measures on a topological space is considered. Convergence of this procedure and a rapidly converging algorithm are studied. Computational aspects of this algorithm along with the ones developed earlier by Wynn, Fedorov, Atwood, Wu and others are provided. Examples discussed are taken from the area of mixture likehoods and optimal experimental design.     

Analysis of multivariate categorical data with misclassification errors by triple sampling schemes

Previous work has been carried out on the use of double-sampling schemes for inference from categorical data subject to misclassification. The double-sampling schemes utilize a sample of n units classified by both a fallible and true device and another sample of n₂ units classified only by a fallible device. In actual applications, one often hasavailable a third sample of n₁ units, which is classified only by the true device. In this article we develop techniques of fitting log-linear models under various misclassification structures for a general triple-sampling scheme. The estimation is by maximum likelihood and the fitted models are hierarchical. The methodology is illustrated by applying it to data in traffic safety research from a study on the effectiveness of belts in reducing injuries.     

A construction of repeated measurements designs with balance for residual effects

Families of Repeated Measurements Designs balanced for residual effects are constructed (whenever the divisibility conditions allow), under the assumption that the number of periods is less than the number of treatments and that each treatment precedes each other treatment once. These designs are then shown to be connected for both residual and direct treatment effects.     

Robust designs for nearly linear regression

In this paper we seek designs and estimators which are optimal in some sense for multivariate linear regression on cubes and simplexes when the true regression function is unknown. More precisely, we assume that the unknown true regression function is the sum of a linear part plus some contamination orthogonal to the set of all linear functions in the L₂ norm with respect to Lebesgue measure. The contamination is assumed bounded in absolute value and it is shown that the usual designs for multivariate linear regression on cubes and simplices and the usual least squares estimators minimize the supremum over all possible contaminations of the expected mean square error. Additional results for extrapolation and interpolation, among other things, are discussed. For suitable loss functions optimal designs are found to have support on the extreme points of our design space.     

Cyclic designs for a covariate model

A linear model with one treatment at V levels and first order regression on K continuous covariates with values on a K-cube is considered. We restrict our attention to classes of designs d for which the number of observations N to be taken is a multiple of V, i.e. N = V × R with R ≥2, and each treatment level is observed R times. Among these designs, called here equireplicated, there is a subclass characterized by the following: the allocation matrix of each treatment level (for short, allocation matrix) is obtained through cyclic permutation of the columns of the allocation matrix of the first treatment level. We call these designs cyclic. Besides having easy representation, the most efficient cyclic designs are often D-optimal in the class of equireplicated designs. A known upper bound for the determinant of the information matrix M(d) of a design, in the class of equireplicated ones, depends on the congruences of N and V modulo 4. For some combinations of parameter moduli, we give here methods of constructing families of D-optimal cyclic designs. Moreover, for some sets of parameters (N, V,K = V), where the upper bound on ∣M(d)∣ (for that specific combination of moduli) is not attainable, it is also possible to construct highly D-efficient cyclic designs. Finally, for N≤24 and V≤6, computer search was used to determine the most efficient design in the class of cyclic ones. They are presented, together with their respective efficiency in the class of equireplicated designs.     

On the normal approximation of an estimate of the mean residual life of a multicomponent system

An estimate of the mean residual life function of a complex system of k independent identically distributed components is proposed and studied with emphasis being on the order of normal approximation.     

Inference for step-stress accelerated life tests

In this paper we consider the more realistic aspect of accelerated life testing wherein the stress on an unfailed item is allowed to increase at a preassigned test time. Such tests are known as step-stress tests. Our approach is nonparametric in that we do not make any assumptions about the underlying distribution of life lengths. We introduce a model for step-stress testing which is based on the ideas of shock models and of wear processes. This model unifies and generalizes two previously proposed models for step-stress testing. We propose an estimator for the life distribution under use conditions stress and show that this estimator is strongly consistent.     

Invariant tests for the equality of k scale parameters under spherical symmetry

We consider tests for scale parameters when the underlying distribution belongs to the class of spherically symmetric laws. A (nx1) random vector x has a spherically symmetric distribution if the distribution of x is identical to the distribution of Px for all (n×n) orthogonal matrices P. Using the principle of invariance we show that the usual normal-theory tests are not only invariant tests but are also exactly robust with respect to this class of spherically symmetric laws.     

On some new search designs for 2m factorial experiments

In this paper, we obtain search designs with reasonably small number of treatments which permit the estimation of the general mean and main effects and search of one more unknown possible nonzero effect among two and three factor interactions in 2^m factorial experiments, 3 ? m ? 8.