Bayesian bridge-randomized penalized quantile regression estimation for linear regression model with AP(q) perturbation

Bridge penalized regression has many desirable statistical properties such as unbiasedness, sparseness as well as ‘oracle’. In Bayesian framework, bridge regularized penalty can be implemented based on generalized Gaussian distribution (GGD) prior. In this paper, we incorporate Bayesian bridge-randomized penalty and its adaptive version into the quantile regression (QR) models with autoregressive perturbations to conduct Bayesian penalization estimation. Employing the working likelihood of the asymmetric Laplace distribution (ALD) perturbations, the Bayesian joint hierarchical models are established. Based on the mixture representations of the ALD and generalized Gaussian distribution (GGD) priors of coefficients, the hybrid algorithms based on Gibbs sampler and Metropolis-Hasting sampler are provided to conduct fully Bayesian posterior estimation. Finally, the proposed Bayesian procedures are illustrated by some simulation examples and applied to a real data application of the electricity consumption.     

Early stopping in seamless phase I/II clinical trials

In recent years, seamless phase I/II clinical trials have drawn much attention, as they consider both toxicity and efficacy endpoints in finding an optimal dose (OD). Engaging an appropriate number of patients in a trial is a challenging task. This paper attempts a dynamic stopping rule to save resources in phase I/II trials. That is, the stopping rule aims to save patients from unnecessary toxic or subtherapeutic doses. We allow a trial to stop early when widths of the confidence intervals for the dose-response parameters become narrower or when the sample size is equal to a predefined size, whichever comes first. The simulation study of dose-response scenarios in various settings demonstrates that the proposed stopping rule can engage an appropriate number of patients. Therefore, we suggest its use in clinical trials.     

Efficient heterogeneous sampling for stochastic simulation with an illustration in health care applications

In modeling disease transmission, contacts are assumed to have different infection rates. A proper simulation must model the heterogeneity in the transmission rates. In this article, we present a computationally efficient algorithm that can be applied to a population with heterogeneous transmission rates. We conducted a simulation study to show that the algorithm is more efficient than other algorithms for sampling the disease transmission in a subset of the heterogeneous population. We use a valid stochastic model of pandemic influenza to illustrate the algorithm and to estimate the overall infection attack rates of influenza A (H1N1) in a Canadian city.     

Bayesian estimation of rare sensitive attribute

Randomized response models have been used to estimate a population proportion of a sensitive attribute. A randomized device is typically employed to protect respondent's privacy in a survey. In addition, an unrelated question is asked to improve the statistical efficiency. In this article, we propose Bayesian estimation of rare sensitive attribute using randomized response technique, which includes a rare unrelated attribute. Two cases are considered, the proportion of a rare unrelated attribute is known and unknown. A simulation study is conducted to assess the performance of the models using mean absolute error and coverage probability. The results show that the performance depends on the parameters and is robust to priors.     

A new confidence interval in errors-in-variables model with known error variance

This paper considers constructing a new confidence interval for the slope parameter in the structural errors-in-variables model with known error variance associated with the regressors. Existing confidence intervals are so severely affected by Gleser–Hwang effect that they are subject to have poor empirical coverage probabilities and unsatisfactory lengths. Moreover, these problems get worse with decreasing reliability ratio which also result in more frequent absence of some existing intervals. To ease these issues, this paper presents a fiducial generalized confidence interval which maintains the correct asymptotic coverage. Simulation results show that this fiducial interval is slightly conservative while often having average length comparable or shorter than the other methods. Finally, we illustrate these confidence intervals with two real data examples, and in the second example some existing intervals do not exist.     

Corrected maximum likelihood estimators in heteroscedastic symmetric nonlinear models

In this article, we derive general matrix formulae for second-order biases of maximum likelihood estimators (MLEs) in a class of heteroscedastic symmetric nonlinear regression models, thus generalizing some results in the literature. This class of regression models includes all symmetric continuous distributions, and has a wide range of practical applications in various fields such as engineering, biology, medicine and economics, among others. The variety of distributions with different kurtosis coefficients than the normal may give more flexibility in the choice of an appropriate distribution, particularly to accommodate outlying and influential observations. We derive a joint iterative process for estimating the mean and dispersion parameters. We also present simulation studies for the biases of the MLEs.     

On the enumeration of rectangular (0, 1)-matrices

The construction and enumeration of (0, 1)-matrices with given line-sums is described for the rectangular cases often encountered in applications. Improved approximations are provided for the number of such matrices. Some new enumeration results for semi-regular bipartite graphs are included, and the related category of the quasi-semiregular bipartite graphs is recognized. The range of certain elements of products of a (0, I)-matrix is considered as a function of the line-sums. This, in turn, is related to the range in the numbers of interchanges available. Improvements in statistical practice that come from these constructions and enumerations are described.     

菲利普斯曲线在中国的有效性研究

从基本的菲利普斯曲线理论出发,提出了新的适应性预期模型,并以此为基础建立附加预期的菲利普斯曲线方程,进而估计出我国近年来的自然失业率水平,由此证明了菲利普斯曲线在我国的有效性,并描述了预期因素对实际通货膨胀水平的影响。最后结合实证分析结果提出解决我国通货膨胀和失业问题的建议,如保证货币政策的连贯性、加强信息披露、解决结构性失业问题等。     

Wavelet Estimator in Nonparametric Regression Model with Dependent Error’s Structure

In this article, we consider a nonparametric regression model with replicated observations based on the dependent error’s structure, for exhibiting dependence among the units. The wavelet procedures are developed to estimate the regression function. The moment consistency, the strong consistency, strong convergence rate and asymptotic normality of wavelet estimator are established under suitable conditions. A simulation study is undertaken to assess the finite sample performance of the proposed method.