Testing Covariance Stationarity

In this paper, we show that the widely used stationarity tests such as the Kwiatkowski Phillips, Schmidt, and Shin (KPSS) test have power close to size in the presence of time-varying unconditional variance. We propose a new test as a complement of the existing tests. Monte Carlo experiments show that the proposed test possesses the following characteristics: (i) in the presence of unit root or a structural change in the mean, the proposed test is as powerful as the KPSS and other tests; (ii) in the presence of a changing variance, the traditional tests perform badly whereas the proposed test has high power comparing to the existing tests; (iii) the proposed test has the same size as traditional stationarity tests under the null hypothesis of stationarity. An application to daily observations of return on U.S. Dollar/Euro exchange rate reveals the existence of instability in the unconditional variance when the entire sample is considered, but stability is found in subsamples.     

Some small-sample results on a bounded influence rank regression method

Naranjo and HeUmansperger (1994) recently derved a bounded influence rank regression method and suggested how hypotheses about the regression coefficients might be tested. This brief note reports some simulation results on how their procedure performs when there is one predictor. Even when the error term is highly skewed, good control over the Type I error probability is obtained Power can be high relative to least squares regression when the error term has a heavy tailed distribution .and the predictor has a symmetric distribution However, if the predictor has a skewed distribution, power can be relatively low even when the distribution of the error term is heavy tailed. Despite this, it is argued that their method provides an important and useful alternative to ordinary least squares as well as other robust regression methods.     

测试技术课程改革与实践

测试技术属于边缘科学,起点高、知识面广、难度大,不仅学科跨度大,涉及机、电、液、光、声、数学及自动控制等几方面,而且该课程实践性很强,实践环节在整个教学过程中占有相当大的比重,因而教与学均存在一定的困难。文章在分析传统教学存在问题的基础上,提出新的教学方法,调整教学内容顺序,突出教学重点,运用工程实例教学法,强化学生的实验训练。     

对应分析统计检验体系探讨

对应分析因其结果的易读性，近些年得到了越来越广泛的应用。为了更好地应用对应分析，提出建立对应分析统计检验体系，包括对应分析适用性的统计检验以及对应分析效果的检验，同时还提出应用对应分析时应注意的其它问题。     

Looking for max-semistability: A new test for the extreme value condition

To test the extreme value condition, Cramér-Von Mises type tests were recently proposed by Drees et al. (2006) and Dietrich et al. (2002). Hüsler and Li (2006) presented a simulation study on the behavior of these tests and verified that they are not robust for models in the domain of attraction of a max-semistable distribution function. In this work we develop a test statistic that distinguishes quite well distribution functions which belong to a max-stable domain of attraction from those in a max-semistable one. The limit law is deduced and the results from a numerical simulation study are presented.     

Inference in Targeted Group‐Sequential Covariate‐Adjusted Randomized Clinical Trials

This article is devoted to the construction and asymptotic study of adaptive, group‐sequential, covariate‐adjusted randomized clinical trials analysed through the prism of the semiparametric methodology of targeted maximum likelihood estimation. We show how to build, as the data accrue group‐sequentially, a sampling design that targets a user‐supplied optimal covariate‐adjusted design. We also show how to carry out sound statistical inference based on such an adaptive sampling scheme (therefore extending some results known in the independent and identically distributed setting only so far), and how group‐sequential testing applies on top of it. The procedure is robust (i.e. consistent even if the working model is mis‐specified). A simulation study confirms the theoretical results and validates the conjecture that the procedure may also be efficient.     

On the asymptotic distribution of cramer-von mises one-sample test statistics under an alternative

The asymptotic normality of the Cramer-von Mises one-sample test statistic and one of its variants under an alternative cdf is demonstrated. The derivation herein is unique in that it does not require knowledge of the theory of weak convergence of probability measures defined on metrized function spaces, and thus is accessible to a broader class of students and practitioners.     

Questions and Answers

In addition to his contributions to biostatistics and clinical trials, Paul Meier had a long-term interest in the legal applications of statistics. As part of this, he had extensive experience as a statistical consultant. Legal consulting can be a minefield, but as a result of his background, Paul had excellent advice to give to those starting out on how to function successfully in this environment.     

Case–control genome-wide joint association study using semiparametric empirical model and approximate Bayes factor

We propose a semiparametric approach for the analysis of case–control genome-wide association study. Parametric components are used to model both the conditional distribution of the case status given the covariates and the distribution of genotype counts, whereas the distribution of the covariates are modelled nonparametrically. This yields a direct and joint modelling of the case status, covariates and genotype counts, and gives a better understanding of the disease mechanism and results in more reliable conclusions. Side information, such as the disease prevalence, can be conveniently incorporated into the model by an empirical likelihood approach and leads to more efficient estimates and a powerful test in the detection of disease-associated SNPs. Profiling is used to eliminate a nuisance nonparametric component, and the resulting profile empirical likelihood estimates are shown to be consistent and asymptotically normal. For the hypothesis test on disease association, we apply the approximate Bayes factor (ABF) which is computationally simple and most desirable in genome-wide association studies where hundreds of thousands to a million genetic markers are tested. We treat the approximate Bayes factor as a hybrid Bayes factor which replaces the full data by the maximum likelihood estimates of the parameters of interest in the full model and derive it under a general setting. The deviation from Hardy–Weinberg Equilibrium (HWE) is also taken into account and the ABF for HWE using cases is shown to provide evidence of association between a disease and a genetic marker. Simulation studies and an application are further provided to illustrate the utility of the proposed methodology.     

Parameter estimation in nonlinear regression models 1

Fisher information contained in record values, inter-record times and their concomitants from a sample of fixed size is derived in general and explicit expressions are deduced for some specific known bivariate classes of distributions. A comparison between fixed sampling and inverse sampling schemes with equal number of records and concomitants is also carried out. We also consider parameter estimation based on bivariate records and a small simulation study is done.