Reducing sample size needed for cox-proportional hazards model analysis using more efficient sampling method

Abstract

In general, survival data are time-to-event data, such as time to death, time to appearance of a tumor, or time to recurrence of a disease. Models for survival data have frequently been based on the proportional hazards model, proposed by Cox. The Cox model has intensive application in the field of social, medical, behavioral and public health sciences. In this paper we propose a more efficient sampling method of recruiting subjects for survival analysis. We propose using a Moving Extreme Ranked Set Sampling (MERSS) scheme with ranking based on an easy-to-evaluate baseline auxiliary variable known to be associated with survival time. This paper demonstrates that this approach provides a more powerful testing procedure as well as a more efficient estimate of hazard ratio than that based on simple random sampling (SRS). Theoretical derivation and simulation studies are provided. The Iowa 65+ Rural study data are used to illustrate the methods developed in this paper.     

Overcoming Old in Age-Friendliness

In this article, we explore views on an age-friendly space in the Netherlands by analysing the responses of older individuals (N = 54) in focus groups and by examining the perspectives around an age-friendly zone in the Netherlands, Parkstad Limburg. We found that a central issue in the wishes for living at a later age are adjustments to envisioned physical limitations that come with the ageing process; this includes adjustments to ensure safety, accessibility and mobility, in order to facilitate older individuals' efforts to stay engaged with the world around them. In their wishes, the older participants constructed ideal dwelling places that closely resembled a senior home, but at the same time they rejected wishing to live in a place that was identified as a senior home. We explain this paradox by the representation of such a space as being for old people, i.e. needy older individuals, which was not how the older participants wished to be identified. We conclude that the conception of age-friendly environments will have to face the difficult challenge of overcoming the association with old age, while simultaneously taking into account adjustments that signify and relate to the ageing process and that seem inescapably tied to oldness.     

Childbearing and Marriage: Investigating the Importance of Context for Meaning-Making of First-Time Marriage

Previous research reveals that the temporal ordering of childbearing and marriage can have an impact on the meaning of first-time marriage. This article aims to obtain a deeper understanding of meaning-making of first-time marriage in relation to childbearing. Narrative interviews with 16 brides and grooms in 8 couples in Sweden were conducted. The material was analyzed in relation to the temporal ordering of childbearing and marriage. The study reveals that the construction of meaning of marriage does not only relate to the temporal context. Social factors such as social class or family formation might also be relevant for how meaning is constructed. This article contributes to a deeper understanding of meaning-making as a relational process constructed within particular contexts.     

Hierarchical Bayesian Modeling of Post-Earthquake Ignition Probabilities Considering Inter-Earthquake Heterogeneity

Post-earthquake fires are high-consequence events with extensive damage potential. They are also low-frequency events, so their nature remains underinvestigated. One difficulty in modeling post-earthquake ignition probabilities is reducing the model uncertainty attributed to the scarce source data. The data scarcity problem has been resolved by pooling the data indiscriminately collected from multiple earthquakes. However, this approach neglects the inter-earthquake heterogeneity in the regional and seasonal characteristics, which is indispensable for risk assessment of future post-earthquake fires. Thus, the present study analyzes the post-earthquake ignition probabilities of five major earthquakes in Japan from 1995 to 2016 (1995 Kobe, 2003 Tokachi-oki, 2004 Niigata–Chuetsu, 2011 Tohoku, and 2016 Kumamoto earthquakes) by a hierarchical Bayesian approach. As the ignition causes of earthquakes share a certain commonality, common prior distributions were assigned to the parameters, and samples were drawn from the target posterior distribution of the parameters by a Markov chain Monte Carlo simulation. The results of the hierarchical model were comparatively analyzed with those of pooled and independent models. Although the pooled and hierarchical models were both robust in comparison with the independent model, the pooled model underestimated the ignition probabilities of earthquakes with few data samples. Among the tested models, the hierarchical model was least affected by the source-to-source variability in the data. The heterogeneity of post-earthquake ignitions with different regional and seasonal characteristics has long been desired in the modeling of post-earthquake ignition probabilities but has not been properly considered in the existing approaches. The presented hierarchical Bayesian approach provides a systematic and rational framework to effectively cope with this problem, which consequently enhances the statistical reliability and stability of estimating post-earthquake ignition probabilities.     

A New Methodology for Before–After Safety Assessment Using Survival Analysis and Longitudinal Data

The widely used empirical Bayes (EB) and full Bayes (FB) methods for before–after safety assessment are sometimes limited because of the extensive data needs from additional reference sites. To address this issue, this study proposes a novel before–after safety evaluation methodology based on survival analysis and longitudinal data as an alternative to the EB/FB method. A Bayesian survival analysis (SARE) model with a random effect term to address the unobserved heterogeneity across sites is developed. The proposed survival analysis method is validated through a simulation study before its application. Subsequently, the SARE model is developed in a case study to evaluate the safety effectiveness of a recent red‐light‐running photo enforcement program in New Jersey. As demonstrated in the simulation and the case study, the survival analysis can provide valid estimates using only data from treated sites, and thus its results will not be affected by the selection of defective or insufficient reference sites. In addition, the proposed approach can take into account the censored data generated due to the transition from the before period to the after period, which has not been previously explored in the literature. Using individual crashes as units of analysis, survival analysis can incorporate longitudinal covariates such as the traffic volume and weather variation, and thus can explicitly account for the potential temporal heterogeneity.     

Juvenile Delinquency Under Conditions of Rapid Social Change

Increased juvenile delinquency can be seen as an indicator for a deteriorating social fabric under conditions of rapid social change. Criminological theories suggest, however, that such conditions do not per se produce delinquency: They force youth into prodelinquent leisure activities with peers, leading to an endorsement of delinquent behavior and offering the infrastructure for it. Resources acquired in family and public life, however, may prevent youth from drifting into such prodelinquent leisure activities and indirectly from delinquent behavior. Empirical tests of these hypotheses have to employ simultaneous analyses of societal-level and individual-level data. On the basis of an international youth study, the paper undertakes such an analysis: In the years 1992–95, data from 42 independent samples of seventh graders from East and West Germany, Poland, Russia, Bulgaria, Slovakia, Hungary, Czechia, and Greece were surveyed. Data on deviant school behavior, delinquent drift, nurturant parenting, and subjective feelings of justice in public were obtained from 7282 thirteen- to fourteen-year-olds. Processes of rapid social change were incorporated as data on changes in GNP in the years proceeding the surveys. Analyses show that delinquent drift is a valid predictor of deviant school behavior only on the individual level. The extent to which adolescents engage in prodelinquent peer activities depends more on the cultural context in which adolescents live than on their personal experience in the family and in public. Nurturant parenting does, however, covary negatively with deviant school behavior irrespective of level of analysis.     

Linguists and other animals

Book reviewed in this article:
Joan Dunayer, Animal Equality: Language and Liberation     

基于WEB的远程教学管理软件分析与设计

本论文主要讨论了基于WEB远程教学管理软件的分析与设计。首先对远程教育与传统教育进行了比较研究,确定远程教育是现代教育发展的方向;其次对开发基于WEB远程教学管理软件进行了环境分析和需求分析;最后讨论了远程教学管理软件的实现,包括软件模块结构设计和网站的总体框架。     

体裁分析在商务语篇教学中的作用

文章介绍了近年来在美国、澳大利亚等国盛行的“体裁教学法”,评价了体裁和体裁分析理论,阐述了体裁分析的发展与特色,探讨了体裁分析法在商务语篇教学中的作用。     

GIS的路径分析算法及实现

讨论了地理信息系统GIS的路径分析算法 ,并在MAPGIS环境下 ,以西南科技大学道路网为例 ,利用VC 及MAPGIS二次开发类库实现了其最短路径和最佳路径分析。