Media Technologies, Images of Drugs, and an Evocative Telepresence

I regard electronic media technologies as framing devices for how viewers perceive issues associated with illegal drugs. Controllers of electronic media technologies produce and disseminate images of illegal drugs and users of such drugs to which viewers respond. People who control the images of electronic media production create an evocative telepresence, or a visual context that relies on appeals to authority and emotion. However, viewers do not merely respond to images of illegal drugs; rather, they actively interpret such images and draw their own conclusions. To demonstrate the complex relationship between electronic stimuli and viewer responses, I report on a classroom experiment comparing those who saw and heard a heroin user with those who only heard this user. I also report findings from student perceptions of and reactions to four drug films. Results of the experiment and the readings of films indicate that viewers, especially those who can see and hear electronic displays, are sophisticated consumers who respond to immediate stimuli while making reference to distal stimuli. In the main, I contend that electronic images of illegal drugs and users in an evocative telepresence are powerful stimuli, but they do not cause viewer perceptions.     

一种应用于药品泡罩包装检测的改进分水岭算法研究

针对分水岭算法存在的过分割问题以及泡罩包装药品图像的特点,提出一种改进的分水岭分割算法对泡罩包装的药品进行分割。该方法将形态学重建运算与使用控制标记符的方法相结合,首先对原图像进行开闭重建,根据邻域像素连通性提取重建后图像的局部极大值作为标记,从而抑制其他的局部极小值,然后依据标记对原始的梯度图像进行修正,最后对修改后的梯度图像进行分水岭分割。试验表明,该方法在缺陷药品检测中,可以有效的抑制传统分水岭的过分割,分割效果良好。     

论毒品犯罪中的诱惑侦查

在毒品案件侦查实践中,诱惑侦查已被大量使用,我国立法应有限度地承认诱惑侦查的合法性,并加强对其规制,建立侦查机关内部监督与检察机关外部监督相结合的监督体制。在司法实践中,应从诱惑侦查主体、适用范围、侦查对象选定、特情的建立和选派、立案及诱惑行为强度等几个方面进行规制。     

药后驾驶纳入危险驾驶罪的证成与构设

在醉酒驾驶和追逐竞速驾驶受到危险驾驶罪规制之后,药后驾驶行为也应当纳入到该罪的范畴内。这是风险刑法语境下的必然要求,也是相同行为相同处理的应有之义。在域外国家和地区立法将药后驾驶行为犯罪化的今天,我国仅仅将产生严重危害后果的药后驾驶按照交通肇事罪或者以危险方法危害公共安全罪来定罪,而将未产生严重危害后果的药后驾驶仅予以行政处罚,存在调控范围不全面、所需构成要件严格和调控手段失调的弊端,可能导致药后驾驶的失控。因此,我国刑法应当将服用毒品和部分合法药品后进行的驾驶作为危险驾驶罪处理,并采纳主客观相结合的证据标准来判断被告人是否构成药后驾驶型的危险驾驶罪。     

Testing for bioequivalence of highly variable drugs from TR‐RT crossover designs with heterogeneous residual variances

Traditional bioavailability studies assess average bioequivalence (ABE) between the test (T) and reference (R) products under the crossover design with TR and RT sequences. With highly variable (HV) drugs whose intrasubject coefficient of variation in pharmacokinetic measures is 30% or greater, assertion of ABE becomes difficult due to the large sample sizes needed to achieve adequate power. In 2011, the FDA adopted a more relaxed, yet complex, ABE criterion and supplied a procedure to assess this criterion exclusively under TRR‐RTR‐RRT and TRTR‐RTRT designs. However, designs with more than 2 periods are not always feasible. This present work investigates how to evaluate HV drugs under TR‐RT designs. A mixed model with heterogeneous residual variances is used to fit data from TR‐RT designs. Under the assumption of zero subject‐by‐formulation interaction, this basic model is comparable to the FDA‐recommended model for TRR‐RTR‐RRT and TRTR‐RTRT designs, suggesting the conceptual plausibility of our approach. To overcome the distributional dependency among summary statistics of model parameters, we develop statistical tests via the generalized pivotal quantity (GPQ). A real‐world data example is given to illustrate the utility of the resulting procedures. Our simulation study identifies a GPQ‐based testing procedure that evaluates HV drugs under practical TR‐RT designs with desirable type I error rate and reasonable power. In comparison to the FDA's approach, this GPQ‐based procedure gives similar performance when the product's intersubject standard deviation is low (≤0.4) and is most useful when practical considerations restrict the crossover design to 2 periods.     

The Extent and Nature of Practitioners,Encounters with Alcohol and Other Drug Use in Social Work and Social Care Practice

This article considers the extent and nature of social work and social care practitioners' experience of working with service users whose lives are affected by the problematic use of alcohol or other drugs (AOD). It draws on the findings of a national study of ‘working with alcohol and drug use’ which was conducted in England in 2010–2011. The study reported here comprised an online survey of front-line practitioners (n = 597), complemented by 12 practitioner focus groups and interviews with 21 key informants from participating local authorities and substance use treatment services. This paper focuses primarily on data from one element of the survey. Findings indicate that the great majority of staff encountered service users who are affected by AOD problems at some level, although there were differences between groups of practitioners in the extent and nature of AOD problems for different groups of service users. The differential experiences of staff according to their client groups underlines the need for education and professional development not only to provide training on working with AOD but to ensure that training is contextualised and relevant to practitioners across the range of social work and social care services.     

A Campus-community Coalition to Control Alcohol-related Problems Off Campus: An Environmental Management Case Study

Abstract

The authors report on the effects of a university and community coalition in preventing problems related to college students' off-campus drinking. The Albany, New York, Committee on University and Community Relations used strategies based on an environmental-management approach that focuses on changing the environment in which individuals make decisions about alcohol consumption and related behaviors. Committee initiatives included improving enforcement of local laws and ordinances, creating a safety-awareness campaign for off-campus students, and developing a comprehensive advertising and beverage-service agreement with local tavern owners. The initiatives were associated with a decline in the number of alcohol-related problems in the community, as indicated by decreases in the number of off-campus noise ordinance reports filed by police and the number of calls to a university-maintained hotline for reporting off-campus problems. An environmental management approach, the authors suggest, has promise as an effective means of preventing alcohol-related problems among college students.     

Forcible,Drug-Facilitated,and Incapacitated Rape and Sexual Assault Among Undergraduate Women

Abstract

Objective: To examine the prevalence of drug-related sexual assaults, identify the frequency of assaults that occur following voluntary versus involuntary drug or alcohol consumption, and identify contextual correlates of drug-related assaults. Participants: College-student females (n = 314). Methods: Volunteers reported experiences with forcible and drug-related sexual assaults in the spring semester of 2004. Follow-up queries regarding the most severe drug-related assaults determined whether the assaults followed voluntary or involuntary alcohol or drug consumption. Results: 29.6% (n = 93) of the respondents reported a drug-related sexual assault or rape; 5.4% (n = 17) reported a forcible sexual assault or rape. Voluntary incapacitation preceded 84.6% of drug-related assaults and involuntary incapacitation preceded 15.4% of drug-related assaults. The majority of drug-related assaults (96.1%) involved alcohol consumption prior to assault. Conclusions: Drug-related sexual assaults on college campuses are more frequent than are forcible assaults and are most frequently preceded by voluntary alcohol consumption.     

筛选免疫药物的单扫描示波极谱法研究

本文用单扫描示波极谱法研究了溶血素的溶血活性,建立了一种筛选免疫药物的新方法。     

Binge Drinking Among Undergraduate College Students in the United States: Implications for Other Substance Use

Abstract

The authors examined the relationship between binge drinking and other substance use among US college students, using nationally representative data from the 1995 National College Health Risk Behavior Survey implemented by the Centers for Disease Control and Prevention. Compared with nonbinge drinkers, current binge drinkers were significantly more likely to report “ever” using and current use of cigarettes, marijuana, cocaine, and other illegal drugs. The researchers also found that the more often students binge drank, the more likely they were to have ever used cigarettes, marijuana, cocaine, and other drugs, and the more likely they were to report current use of cigarettes and marijuana. Those who design programs to prevent binge drinking and use of other substances should take into account the reality that many students use more than one substance and that the more frequently students report binge drinking, the more likely they are to be using other substances as well.