On L 1-consistency of kernel-type density estimator for stationary markov processes

A convergence result for kernel type density estimators, proved by Devroye and Gyrofi (1985), is extended to stationary Markov processess satisfying (G ₂-condition introduced by Rosenblatt (1970).     

On Block Skip Free Transition Matrices and First Passage Times

Starting from an abstract setting which extends the property “skip free to the left” for transition matrices to a partition of the state space, we develop bounds for the mean hitting time of a Markov chain to an arbitrary subset from an arbitrary initial law. We apply our theory to the embedded Markov chains associated with the M/G/1 and the GI/M/1 queueing systems. We also illustrate its applicability with an asymptotic analysis of a non-reversible Markovian star queueing network with losses.     

A multivariate version of Gini's rank association coefficient

In this paper, we introduce a multivariate generalization of the population version of Gini's rank association coefficient, giving a response to this open question posed in [4]. We also study some properties of this version, present the corresponding results for the sample statistic, and provide several examples.     

On the detection of changes in autoregressive time series I. Asymptotics

Various test statistics are discussed which can be used for detecting changes in the parameters of an autoregressive time series. In this first part of our study, the limiting behavior of the test statistics is derived under the null hypothesis of no change as well as under alternatives. In a forthcoming second part of our investigation, these asymptotic results will be compared to some corresponding bootstrap procedures, and a small simulation study will be conducted.     

Wilcoxon–Mann–Whitney test for stratified samples and Efron's paradox dice

Two-treatment multi-center clinical trials are the most common type of clinical trials in practice. The aim of this paper is to discuss a curious property of certain standard nonparametric procedures used in the analysis of such clinical trials. Different analyses of a simulated data example are presented, which lead to contrasting and surprising results. The source of the potentially misleading outcome is then explored while relating the simulated data with the concept of Efron's paradox dice and the notion of nontransitivity. With the root of the problem established, an alternate nonparametric method from the literature is shown to address the problem. Finally, pointing out an interpretational concern of using the alternate procedure, a modification to this procedure is also suggested and corresponding theoretical results are presented.     

Normal approximation to the hypergeometric distribution in nonstandard cases and a sub-Gaussian Berry–Esseen theorem

In this paper, we consider simple random sampling without replacement from a dichotomous finite population. We investigate accuracy of the Normal approximation to the Hypergeometric probabilities for a wide range of parameter values, including the nonstandard cases where the sampling fraction tends to one and where the proportion of the objects of interest in the population tends to the boundary values, zero and one. We establish a non-uniform Berry–Esseen theorem for the Hypergeometric distribution which shows that in the nonstandard cases, the rate of Normal approximation to the Hypergeometric distribution can be considerably slower than the rate of Normal approximation to the Binomial distribution. We also report results from a moderately large numerical study and provide some guidelines for using the Normal approximation to the Hypergeometric distribution in finite samples.     

Multivariate inverse Gaussian distribution as a limit of multivariate waiting time distributions

Multivariate inverse Gaussian distribution proposed by Minami [2003. A multivariate extension of inverse Gaussian distribution derived from inverse relationship. Commun. Statist. Theory Methods 32(12), 2285–2304] was derived through multivariate inverse relationship with multivariate Gaussian distributions and characterized as the distribution of the location at a certain stopping time of a multivariate Brownian motion. In this paper, we show that the multivariate inverse Gaussian distribution is also a limiting distribution of multivariate Lagrange distributions, which is a family of waiting time distributions, under certain conditions.     

A sequential design for a clinical trial with a linear prognostic factor

We study a randomized adaptive design to assign one of the L$L$ treatments to patients who arrive sequentially by means of an urn model. At each stage n$n$, a reward is distributed between treatments. The treatment applied is rewarded according to its response, 0?_Yn?1$0?Y_n?1$, and 1-_Yn$1-Y_n$ is distributed among the other treatments according to their performance until stage n-1$n-1$. Patients can be classified in K+1$K+1$ levels and we assume that the effect of this level in the response to the treatments is linear. We study the asymptotic behavior of the design when the ordinary least square estimators are used as a measure of performance until stage n-1$n-1$.     

肾叶唐松草微量元素和氨基酸的测定

本文利用原子吸收光谱法测定了中药肾叶唐松草中所含14种微量元素,利用氨基酸分析仪对它所含的氨基酸进行了鉴定及含量测定,并对根、茎、叶等不同部位的微量元素和氨基酸含量分别做了比较。