Accuracy of approximate progressively censored reliability sampling plans for exponential models

Reliability sampling plans provide an efficient method to determine the acceptability of a product based upon the lifelengths of some test units. Usually, they depend on the producer and consumer’s quality requirements and do not admit closed form solutions. Acceptance sampling plans for one- and two-parameter exponential lifetime models, derived by approximating the operating characteristic curve, are presented in this paper. The accuracy of these approximate plans, which are explicitly expressible and valid for failure and progressive censoring, is assessed. The approximation proposed in the one-parameter case is found to be practically exact. Explicit lower and upper bounds on the smallest sample size are given in the two-parameter case. Some additional advantages are also pointed out.     

Missing item imputation for quality-of-life instruments with application to asthma quality-of-life questionnaires

There has been increasing use of quality-of-life (QoL) instruments in drug development. Missing item values often occur in QoL data. A common approach to solve this problem is to impute the missing values before scoring. Several imputation procedures, such as imputing with the most correlated item and imputing with a row/column model or an item response model, have been proposed. We examine these procedures using data from two clinical trials, in which the original asthma quality-of-life questionnaire (AQLQ) and the miniAQLQ were used. We propose two modifications to existing procedures: truncating the imputed values to eliminate outliers and using the proportional odds model as the item response model for imputation. We also propose a novel imputation method based on a semi-parametric beta regression so that the imputed value is always in the correct range and illustrate how this approach can easily be implemented in commonly used statistical software. To compare these approaches, we deleted 5% of item values in the data according to three different missingness mechanisms, imputed them using these approaches and compared the imputed values with the true values. Our comparison showed that the row/column-model-based imputation with truncation generally performed better, whereas our new approach had better performance under a number scenarios.     

Nonparametric control charts based on runs and Wilcoxon-type rank-sum statistics

In this article, we introduce three new distribution-free Shewhart-type control charts that exploit run and Wilcoxon-type rank-sum statistics to detect possible shifts of a monitored process. Exact formulae for the alarm rate, the run length distribution, and the average run length (ARL) are all derived. A key advantage of these charts is that, due to their nonparametric nature, the false alarm rate (FAR) and in-control run length distribution is the same for all continuous process distributions. Tables are provided for the implementation of the charts for some typical FAR values. Furthermore, a numerical study carried out reveals that the new charts are quite flexible and efficient in detecting shifts to Lehmann-type out-of-control situations.     

Cumulative correspondence analysis of ordered categorical data from industrial experiments

Most studies of quality improvement deal with ordered categorical data from industrial experiments. Accounting for the ordering of such data plays an important role in effectively determining the optimal factor level of combination. This paper utilizes the correspondence analysis to develop a procedure to improve the ordered categorical response in a multifactor state system based on Taguchi's statistic. Users may find the proposed procedure in this paper to be attractive because we suggest a simple and also popular statistical tool for graphically identifying the really important factors and determining the levels to improve process quality. A case study for optimizing the polysilicon deposition process in a very large-scale integrated circuit is provided to demonstrate the effectiveness of the proposed procedure.     

Estimation of Distribution Functions Using Data from Different Environments

Suppose that when a unit operatesin a certain environment, its lifetime has distribution G,and when the unit operates in another environment, its lifetimehas a different distribution, say F. Moreover, supposethe unit is operated for a certain period of time in the firstenvironment and is then transferred to the second environment.Thus we observe a censored lifetime in the first environmentand a failure time of a ``used' unit in the second environment.We propose an EM algorithm approach for obtaining a self-consistentestimator of F. Moreover, suppose using observations from both environments.The case where failure times are subject to right censoring isconsidered as well. We also establish the maximum likelihoodestimator of F. Moreover, suppose when the unit is repairable. Applicationand simulation studies are presented to illustrate the methodsderived.     

Random regression models for human immunodeficiency virus ribonucleic acid data subject to left censoring and informative drop-outs

Objectives in many longitudinal studies of individuals infected with the human immunodeficiency virus (HIV) include the estimation of population average trajectories of HIV ribonucleic acid (RNA) over time and tests for differences in trajectory across subgroups. Special features that are often inherent in the underlying data include a tendency for some HIV RNA levels to be below an assay detection limit, and for individuals with high initial levels or high ranges of change to drop out of the study early because of illness or death. We develop a likelihood for the observed data that incorporates both of these features. Informative drop-outs are handled by means of an approach previously published by Schluchter. Using data from the HIV Epidemiology Research Study, we implement a maximum likelihood procedure to estimate initial HIV RNA levels and slopes within a population, compare these parameters across subgroups of HIV-infected women and illustrate the importance of appropriate treatment of left censoring and informative drop-outs. We also assess model assumptions and consider the prediction of random intercepts and slopes in this setting. The results suggest that marked bias in estimates of fixed effects, variance components and standard errors in the analysis of HIV RNA data might be avoided by the use of methods like those illustrated.     

Profile upper Confidence Limits from Discrete Data

When the data are discrete, standard approximate confidence limits often have coverage well below nominal for some parameter values. While ad hoc adjustments may largely solve this problem for particular cases, Kabaila & Lloyd (1997) gave a more systematic method of adjustment which leads to tight upper limits, which have coverage which is never below nominal and are as small as possible within a particular class. However, their computation for all but the simplest models is infeasible. This paper suggests modifying tight upper limits by an initial replacement of the unknown nuisance parameter vector by its profile maximum likelihood estimator. While the resulting limits no longer possess the optimal properties of tight limits exactly, the paper presents both numerical and theoretical evidence that the resulting coverage function is close to optimal. Moreover these profile upper limits are much (possibly many orders of magnitude) easier to compute than tight upper limits.     

Estimation of nonseparable models with censored dependent variables and endogenous regressors

In this article we develop a nonparametric estimator for the local average response of a censored dependent variable to endogenous regressors in a nonseparable model where the unobservable error term is not restricted to be scalar and where the nonseparable function need not be monotone in the unobservables. We formalize the identification argument put forward in Altonji, Ichimura, and Otsu (2012 Altonji, J. G., Ichimura, H., Otsu, T. (2012). Estimating derivatives in nonseparable models with limited dependent variables. Econometrica 80:1701–1719.[Crossref], [Web of Science ®] , [Google Scholar]), construct a nonparametric estimator, characterize its asymptotic property, and conduct a Monte Carlo investigation to study its small sample properties. Identification is constructive and is achieved through a control function approach. We show that the estimator is consistent and asymptotically normally distributed. The Monte Carlo results are encouraging.     

Transition probabilities and ARL performance of Six Sigma zone control charts

In this article, Six Sigma zone control charts (SSZCCs) are proposed for world class organizations. The transition probabilities are obtained using the Markov chain approach. The Average Run Length (ARL) values are then presented. The ARL performance of the proposed SSZCCs and the standard Six Sigma control chart (SSCC) without zones or run rules is studied. The ARL performance of these charts is then compared with those of the other standard zone control charts (ZCCs), the modified ZCC and the traditional Shewhart control chart (SCC) with common run rules. As expected, it is shown that the proposed SSZCC outperforms the standard SSCC without zones or run rules for process shifts of any magnitude. When compared to the other standard ZCCs and the Shewhart chart with common run rules, it is observed that the proposed SSZCCs have much higher false alarm rates for smaller shifts and hence they prevent unwanted process disturbances. The application of the proposed SSZCC is illustrated using a real time example.