Reliability estimation in stress–strength models: an MCMC approach

In this paper, we consider the estimation of the stress–strength parameter R=P(Y<X) when X and Y are independent and both are modified Weibull distributions with the common two shape parameters but different scale parameters. The Markov Chain Monte Carlo sampling method is used for posterior inference of the reliability of the stress–strength model. The maximum-likelihood estimator of R and its asymptotic distribution are obtained. Based on the asymptotic distribution, the confidence interval of R can be obtained using the delta method. We also propose a bootstrap confidence interval of R. The Bayesian estimators with balanced loss function, using informative and non-informative priors, are derived. Different methods and the corresponding confidence intervals are compared using Monte Carlo simulations.     

Bayes sequential estimation for a Poisson process under a LINEX loss function

In this paper, within the framework of a Bayesian model, we consider the problem of sequentially estimating the intensity parameter of a homogeneous Poisson process with a linear exponential (LINEX) loss function and a fixed cost per unit time. An asymptotically pointwise optimal (APO) rule is proposed. It is shown to be asymptotically optimal for the arbitrary priors and asymptotically non-deficient for the conjugate priors in a similar sense of Bickel and Yahav [Asymptotically pointwise optimal procedures in sequential analysis, in Proceedings of the Fifth Berkeley Symposium on Mathematical Statistics and Probability, Vol. 1, University of California Press, Berkeley, CA, 1967, pp. 401–413; Asymptotically optimal Bayes and minimax procedures in sequential estimation, Ann. Math. Statist. 39 (1968), pp. 442–456] and Woodroofe [A.P.O. rules are asymptotically non-deficient for estimation with squared error loss, Z. Wahrsch. verw. Gebiete 58 (1981), pp. 331–341], respectively. The proposed APO rule is illustrated using a real data set.     

Bayes Estimation Based on Joint Progressive Type II Censored Data Under LINEX Loss Function

In the lifetime experiments, the joint censoring scheme is useful for planning comparative purposes of two identical products manufactured coming from different lines. In this article, we will confine ourselves to the data obtained by conducting a joint progressive Type II censoring scheme on the basis of the two combined samples selected from the two lines. Moreover, it is supposed that the distributions of lifetimes of the two products satisfy in a proportional hazard model. A general form for the distributions is considered, and we tackle the problem of obtaining Bayes estimates under the squared error and linear-exponential (LINEX) loss functions. As a special case, the Weibull distribution is discussed in more detail. Finally, the estimated risks of the various estimators obtained are compared using the Monte Carlo method.     

Case–control genome-wide joint association study using semiparametric empirical model and approximate Bayes factor

We propose a semiparametric approach for the analysis of case–control genome-wide association study. Parametric components are used to model both the conditional distribution of the case status given the covariates and the distribution of genotype counts, whereas the distribution of the covariates are modelled nonparametrically. This yields a direct and joint modelling of the case status, covariates and genotype counts, and gives a better understanding of the disease mechanism and results in more reliable conclusions. Side information, such as the disease prevalence, can be conveniently incorporated into the model by an empirical likelihood approach and leads to more efficient estimates and a powerful test in the detection of disease-associated SNPs. Profiling is used to eliminate a nuisance nonparametric component, and the resulting profile empirical likelihood estimates are shown to be consistent and asymptotically normal. For the hypothesis test on disease association, we apply the approximate Bayes factor (ABF) which is computationally simple and most desirable in genome-wide association studies where hundreds of thousands to a million genetic markers are tested. We treat the approximate Bayes factor as a hybrid Bayes factor which replaces the full data by the maximum likelihood estimates of the parameters of interest in the full model and derive it under a general setting. The deviation from Hardy–Weinberg Equilibrium (HWE) is also taken into account and the ABF for HWE using cases is shown to provide evidence of association between a disease and a genetic marker. Simulation studies and an application are further provided to illustrate the utility of the proposed methodology.     

Comparing the relative efficiency of three sequential procedures

We consider the sequential procedures developed by Robbins and Siegmund (1974), Louis (1975) and Zoubeidi (1992) for comparing the means of two treatments. We let the procedures have equal power functions and compare their Bayes and minimax risks using the invariance property of their power functions. For each of several formulations of the problem we determine the most relatively efficient procedure and compute its expected total sample size.     

The umvue and bayes estimate of reliability of mixed failure time distribution

We study the reliability estimates of the non-standard mixture of degenerate (degenerated at zero) and exponential distributions. The Uniformly Minimum Variance Unbiased Estimator (UMVUE) and Bayes estimator of the reliability for some selective prior when the mixing proportion is known and unknown are derived. The Bayes risk is computed for each Bayes estimator of the reliability. A simulated study is carried out to assess the performance of the estimators alongwith the true and Maximum Likelihood Estimate (MLE) of the reliability. An example from Vannman (1991) is also discussed at the end of the paper.     

Small sample study on estimators of life distributions and of mean survival times using randomly censored data

Whereas large-sample properties of the estimators of survival distributions using censored data have been studied by many authors, exact results for small samples have been difficult to obtain. In this paper we obtain the exact expression for the ath moment (a > 0) of the Bayes estimator of survival distribution using the censored data under proportional hazard model. Using the exact expression we compute the exact mean, variance and MSE of the Bayes estimator. Also two estimators ofthe mean survival time based on the Kaplan-Meier estimator and the Bayes estimator are compared for small samples under proportional hazards.     

On the estimation of the true probability of a correct selection

For ranking and selection problems, the true probabiIity of a correct selection P(CS) is unknown even if a selection is made under the indifference-zone approach. Thus to estimate the true P(CS) some Bayes estimators and a bootstrap estimator are proposed for two normcal populations with common known variance. Also a bootstrap estimator and a bootstrap confidence interval are proposed for normal populations with common unknown variance. Some comparisons between proposed estimators and some other known estimators are made via Monte Carlo simulations.     

Hierarchical bayes quality measurement plan

Quality Measurement Plan (QMP) as developed by Hoadley (1981) is a statistical method for analyzing discrete quality audit data which consist of the expected number of defects given the standard quality. The QMP is based on an empirical Bayes (EB) model of the audit sampling process. Despite its wide publicity, Hoadley's method has often been described as heuristic. In this paper we offer an hierarchical Bayes (HB) alternative to Hoadley's EB model, and overcome much of the criticism against this model. Gibbs sampling is used to implement the HB model proposed in this paper. Also, the convergence of the Gibbs sampler is monitored via the algorithm of Gelman and Rubin (1992).     

A generalization of the compound rayleigh distribution: using a bayesian method on cancer survival times

In this paper the generalized compound Rayleigh model, exhibiting flexible hazard rate, is high¬lighted. This makes it attractive for modelling survival times of patients showing characteristics of a random hazard rate. The Bayes estimators are derived for the parameters of this model and some survival time parameters from a right censored sample. This is done with respect to conjugate and discrete priors on the parameters of this model, under the squared error loss function, Varian's asymmetric linear-exponential (linex) loss function and a weighted linex loss function. The future survival time of a patient is estimated under these loss functions. A Monte Carlo simu¬lation procedure is used where closed form expressions of the estimators cannot be obtained. An example illustrates the proposed estimators for this model.