Confidence Intervals for a Binomial Parameter after Observing No Successes

The easily computed, one-sided confidence interval for the binomial parameter provides the basis for an interesting classroom example of scientific thinking and its relationship to confidence intervals. The upper limit can be represented as the sample proportion from a number of “successes” in a future experiment of the same sample size. The upper limit reported by most people corresponds closely to that producing a 95 percent classical confidence interval and has a Bayesian interpretation.     

A Class of Multivariate Bilateral Selection t Distributions and Its Properties

This article proposes a class of multivariate bilateral selection t distributions useful for analyzing non-normal (skewed and/or bimodal) multivariate data. The class is associated with a bilateral selection mechanism, and it is obtained from a marginal distribution of the centrally truncated multivariate t. It is flexible enough to include the multivariate t and multivariate skew-t distributions and mathematically tractable enough to account for central truncation of a hidden t variable. The class, closed under linear transformation, marginal, and conditional operations, is studied from several aspects such as shape of the probability density function, conditioning of a distribution, scale mixtures of multivariate normal, and a probabilistic representation. The relationships among these aspects are given, and various properties of the class are also discussed. Necessary theories and two applications are provided.     

Adaptive Lasso Variable Selection for the Accelerated Failure Models

This article considers the adaptive lasso procedure for the accelerated failure time model with multiple covariates based on weighted least squares method, which uses Kaplan-Meier weights to account for censoring. The adaptive lasso method can complete the variable selection and model estimation simultaneously. Under some mild conditions, the estimator is shown to have sparse and oracle properties. We use Bayesian Information Criterion (BIC) for tuning parameter selection, and a bootstrap variance approach for standard error. Simulation studies and two real data examples are carried out to investigate the performance of the proposed method.     

Bayesian Analysis of Two-Regime Threshold Autoregressive Moving Average Model with Exogenous Inputs

We consider Bayesian analysis of threshold autoregressive moving average model with exogenous inputs (TARMAX). In order to obtain the desired marginal posterior distributions of all parameters including the threshold value of the two-regime TARMAX model, we use two different Markov chain Monte Carlo (MCMC) methods to apply Gibbs sampler with Metropolis-Hastings algorithm. The first one is used to obtain iterative least squares estimates of the parameters. The second one includes two MCMC stages for estimate the desired marginal posterior distributions and the parameters. Simulation experiments and a real data example show support to our approaches.     

Zenga Distribution and Inequality Ordering

The aim of this article is to establish an ordering related to the inequality for the recently introduced Zenga distribution. In addition to the well-known order based on the Lorenz curve, the order based on I(p) curve is considered. Since the Zenga distribution seems to be suitable to model wealth, financial, actuarial, and, especially, income distributions, these findings are fundamental in the understanding of how parameter values are related to inequality. This investigation shows that for the Zenga distribution, two of the three parameters are inequality indicators.     

Penalized inverse probability weighted estimators for weighted rank regression with missing covariates

Abstract

In this article, we study the variable selection and estimation for linear regression models with missing covariates. The proposed estimation method is almost as efficient as the popular least-squares-based estimation method for normal random errors and empirically shown to be much more efficient and robust with respect to heavy tailed errors or outliers in the responses and covariates. To achieve sparsity, a variable selection procedure based on SCAD is proposed to conduct estimation and variable selection simultaneously. The procedure is shown to possess the oracle property. To deal with the covariates missing, we consider the inverse probability weighted estimators for the linear model when the selection probability is known or unknown. It is shown that the estimator by using estimated selection probability has a smaller asymptotic variance than that with true selection probability, thus is more efficient. Therefore, the important Horvitz-Thompson property is verified for penalized rank estimator with the covariates missing in the linear model. Some numerical examples are provided to demonstrate the performance of the estimators.     

Selection of bandwidth for kernel regression

ABSTRACT

The most important factor in kernel regression is a choice of a bandwidth. Considerable attention has been paid to extension the idea of an iterative method known for a kernel density estimate to kernel regression. Data-driven selectors of the bandwidth for kernel regression are considered. The proposed method is based on an optimally balanced relation between the integrated variance and the integrated square bias. This approach leads to an iterative quadratically convergent process. The analysis of statistical properties shows the rationale of the proposed method. In order to see statistical properties of this method the consistency is determined. The utility of the method is illustrated through a simulation study and real data applications.     

Gamma shared frailty model based on reversed hazard rate

Abstract

Frailty models are used in survival analysis to account for unobserved heterogeneity in individual risks to disease and death. To analyze bivariate data on related survival times (e.g., matched pairs experiments, twin, or family data), shared frailty models were suggested. Shared frailty models are frequently used to model heterogeneity in survival analysis. The most common shared frailty model is a model in which hazard function is a product of random factor(frailty) and baseline hazard function which is common to all individuals. There are certain assumptions about the baseline distribution and distribution of frailty. In this paper, we introduce shared gamma frailty models with reversed hazard rate. We introduce Bayesian estimation procedure using Markov Chain Monte Carlo (MCMC) technique to estimate the parameters involved in the model. We present a simulation study to compare the true values of the parameters with the estimated values. Also, we apply the proposed model to the Australian twin data set.     

Lasso with convex loss: Model selection consistency and estimation

Abstract

Variable selection is a fundamental challenge in statistical learning if one works with data sets containing huge amount of predictors. In this artical we consider procedures popular in model selection: Lasso and adaptive Lasso. Our goal is to investigate properties of estimators based on minimization of Lasso-type penalized empirical risk with a convex loss function, in particular nondifferentiable. We obtain theorems concerning rate of convergence in estimation, consistency in model selection and oracle properties for Lasso estimators if the number of predictors is fixed, i.e. it does not depend on the sample size. Moreover, we study properties of Lasso and adaptive Lasso estimators on simulated and real data sets.     

An improved comorbidity summary score for measuring disease burden and predicting mortality with applications to two national cohorts

Abstract

Research involving administrative healthcare data to study patient outcomes requires the investigator to account for the patient’s disease burden in order to reduce the potential for biased results. Here we develop a comorbidity summary score based on variable importance measures derived from several statistical and machine learning methods and show it has superior predictive performance to the Elixhauser and Charlson indices when used to predict 1-year, 5-year, and 10-year mortality. We used two large Veterans Administration cohorts to develop and validate the summary score and compared predictive performance using the area under ROC curve (AUC) and the Brier score.