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11.
The Wisconsin Epidemiologic Study of Diabetic Retinopathy is a population-based epidemiological study carried out in Southern Wisconsin during the 1980s. The resulting data were analysed by different statisticians and ophthalmologists during the last two decades. Most of the analyses were carried out on the baseline data, although there were two follow-up studies on the same population. A Bayesian analysis of the first follow-up data, taken four years after the baseline study, was carried out by Angers and Biswas [Angers, J.-F. and Biswas, A., 2004, A Bayesian analysis of the four-year follow-up data of theWisconsin epidemiologic study of diabetic retinopathy. Statistics in Medicine, 23, 601–615.], where the choice of the best model in terms of the covariate inclusion is done, and estimates of the associated covariate effects were obtained using the baseline data to set the prior for the parameters. In the present article we consider an univariate transformation of the bivariate ordinal data, and a parallel analysis with the much simpler univariate data is carried out. The results are then compared with the results of Angers and Biswas (2004). In conclusion, our analyses suggest that the univariate analysis fails to detect features of the data found by the bivariate analysis. Even an univariate transformation of our data with quite high correlation with both left and right eyes is inadequate.  相似文献   
12.
Many research fields increasingly involve analyzing data of a complex structure. Models investigating the dependence of a response on a predictor have moved beyond the ordinary scalar-on-vector regression. We propose a regression model for a scalar response and a surface (or a bivariate function) predictor. The predictor has a random component and the regression model falls in the framework of linear random effects models. We estimate the model parameters via maximizing the log-likelihood with the ECME (Expectation/Conditional Maximization Either) algorithm. We use the approach to analyze a data set where the response is the neuroticism score and the predictor is the resting-state brain function image. In the simulations we tried, the approach has better performance than two other approaches, a functional principal component regression approach and a smooth scalar-on-image regression approach.  相似文献   
13.
In a recent research, the quasi-likelihood estimation methodology was developed to estimate the regression effects in the Generalized BINMA(1) (GBINMA(1)) process. The method provides consistent parameter estimates but, in the intermediate computations, moment estimating equations were used to estimate the serial- and cross-correlation parameters. This procedure may not result optimal parameter estimates, in particular, for the regression effects. This paper provides an alternative simpler GBINMA(1) process based on multivariate thinning properties where the main effects are estimated via a robust generalized quasi-likelihood (GQL) estimation approach. The two techniques are compared through some simulation experiments. A real-life data application is studied.  相似文献   
14.
本文基于微观调查数据,利用有序Probit模型对影响我国西部地区高校教师薪酬满意度的因素进行了系统分析。研究发现:西部地区高校教师薪酬满意度整体水平不高;文化程度、职称、平均月收入、薪酬与消费水平匹配感、薪酬外部公平感、岗位津贴满意感、教学及科研津贴满意感、绩效薪酬考核满意感、薪酬激励作用满意感等因素对西部地区高校教师薪酬满意度的影响显著。针对影响显著的因素,本文提出提高西部地区高校教师薪酬满意度的对策建议。  相似文献   
15.
This study contributes to the general knowledge of the victim–offender overlap by determining whether the phenomenon exists among older adults and whether known correlates of crime and victimization explain the relationship. Cross-sectional survey data from telephone interviews conducted with individuals 60 years and older (N = 2,000) residing in Arizona and Florida are used to estimate confirmatory factor models for both victimization and criminal offending. The results from a series of multivariate regression models show that victimization is associated with criminal offending. While factors such as low self-control, depression, and spending time in commercial drinking establishments partially attenuate the victimization–crime link, the statistically significant relationship persists in a multivariate context. Further testing indicates that the observed findings are robust across measurement and modeling strategies. Coupled with prior research, the results support the argument that the victim–offender overlap exists (and is difficult to explain) over the life course.  相似文献   
16.
A strictly nonparametric bivariate test for two sample location problem is proposed. The proposed test is easy to apply and does not require the stringent condition of affine-symmetry or elliptical symmetry which is required by some of the major tests available for the same problem. The power function of the proposed test is calculated. The asymptotic distribution of the proposed test statistic is found to be normal. The power of proposed test is compared with some of the well-known tests under various distributions using Monte Carlo simulation technique. The power study shows that the proposed test statistic performs better than most of the test statistics for almost all the distributions considered here. As soon as the underlying population structure deviates from normality, the ability of the proposed test statistic to detect the smallest shift in location increases as compared to its competitors. The application of the test is shown by using a data set.  相似文献   
17.
A fully parametric first-order autoregressive (AR(1)) model is proposed to analyse binary longitudinal data. By using a discretized version of a copula, the modelling approach allows one to construct separate models for the marginal response and for the dependence between adjacent responses. In particular, the transition model that is focused on discretizes the Gaussian copula in such a way that the marginal is a Bernoulli distribution. A probit link is used to take into account concomitant information in the behaviour of the underlying marginal distribution. Fixed and time-varying covariates can be included in the model. The method is simple and is a natural extension of the AR(1) model for Gaussian series. Since the approach put forward is likelihood-based, it allows interpretations and inferences to be made that are not possible with semi-parametric approaches such as those based on generalized estimating equations. Data from a study designed to reduce the exposure of children to the sun are used to illustrate the methods.  相似文献   
18.
We consider here a generalization of the skew-normal distribution, GSN(λ1,λ2,ρ), defined through a standard bivariate normal distribution with correlation ρ, which is a special case of the unified multivariate skew-normal distribution studied recently by Arellano-Valle and Azzalini [2006. On the unification of families of skew-normal distributions. Scand. J. Statist. 33, 561–574]. We then present some simple and useful properties of this distribution and also derive its moment generating function in an explicit form. Next, we show that distributions of order statistics from the trivariate normal distribution are mixtures of these generalized skew-normal distributions; thence, using the established properties of the generalized skew-normal distribution, we derive the moment generating functions of order statistics, and also present expressions for means and variances of these order statistics.Next, we introduce a generalized skew-tν distribution, which is a special case of the unified multivariate skew-elliptical distribution presented by Arellano-Valle and Azzalini [2006. On the unification of families of skew-normal distributions. Scand. J. Statist. 33, 561–574] and is in fact a three-parameter generalization of Azzalini and Capitanio's [2003. Distributions generated by perturbation of symmetry with emphasis on a multivariate skew t distribution. J. Roy. Statist. Soc. Ser. B 65, 367–389] univariate skew-tν form. We then use the relationship between the generalized skew-normal and skew-tν distributions to discuss some properties of generalized skew-tν as well as distributions of order statistics from bivariate and trivariate tν distributions. We show that these distributions of order statistics are indeed mixtures of generalized skew-tν distributions, and then use this property to derive explicit expressions for means and variances of these order statistics.  相似文献   
19.
Both treatment efficacy and safety are typically the primary endpoints in Phase II, and even in some Phase III, clinical trials. Efficacy is frequently measured by time to response, death, or some other milestone event and thus is a continuous, possibly censored, outcome. Safety, however, is frequently measured on a discrete scale; in Eastern Cooperative Oncology Group clinical trial E2290, it was measured as the number of weekly rounds of chemotherapy that were tolerable to colorectal cancer patients. For the joint analysis of efficacy and safety, we propose a non-parametric, computationally simple estimator for the bivariate survival function when one time-to-event is continuous, one is discrete, and both are subject to right-censoring. The bivariate censoring times may depend on each other, but they are assumed to be independent of both event times. We derive a closed-form covariance estimator for the survivor function which allows for inference to be based on any of several possible statistics of interest. In addition, we derive its covariance with respect to calendar time of analysis, allowing for its use in sequential studies.  相似文献   
20.
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