Exploring the link between government funding and efficiency in nonprofit colleges

Previous literature has suggested that federal funding can hinder the efficiency of nonprofit organizations, but this has yet not been empirically tested. This study used a two‐stage data envelopment analysis (DEA) model to measure the efficiency of a set of private nonprofit teaching‐oriented colleges, then estimate the impact of federal and state funding on organizational efficiency. The findings indicate that, on average, increases in neither state nor federal funding effect efficiency of nonprofit colleges. Increasing state funding negatively impacted the efficiency of public colleges (N = 799). This study suggests that the challenges for nonprofits that accompany government funding may not rise to a quantifiable negative effect on efficiency.     

自主创业——青年学生就业的重要途径

在未来一段时期,我国面临的就业压力依然很大.要解决大学生就业难,自主创业是一条重要途径.为此,青年学生要注意培养自我创业的意识和企业家精神.学校应建立学生创业长效机制,在课程设置等方面加大创业型学生培养力度.近几年来,政府及有关部门,正努力为青年学生自主创业创造良好的外部环境.     

An elastic-net penalized expectile regression with applications

To perform variable selection in expectile regression, we introduce the elastic-net penalty into expectile regression and propose an elastic-net penalized expectile regression (ER-EN) model. We then adopt the semismooth Newton coordinate descent (SNCD) algorithm to solve the proposed ER-EN model in high-dimensional settings. The advantages of ER-EN model are illustrated via extensive Monte Carlo simulations. The numerical results show that the ER-EN model outperforms the elastic-net penalized least squares regression (LSR-EN), the elastic-net penalized Huber regression (HR-EN), the elastic-net penalized quantile regression (QR-EN) and conventional expectile regression (ER) in terms of variable selection and predictive ability, especially for asymmetric distributions. We also apply the ER-EN model to two real-world applications: relative location of CT slices on the axial axis and metabolism of tacrolimus (Tac) drug. Empirical results also demonstrate the superiority of the ER-EN model.     

Outlier detection and robust variable selection via the penalized weighted LAD-LASSO method

This paper studies the outlier detection and robust variable selection problem in the linear regression model. The penalized weighted least absolute deviation (PWLAD) regression estimation method and the adaptive least absolute shrinkage and selection operator (LASSO) are combined to simultaneously achieve outlier detection, and robust variable selection. An iterative algorithm is proposed to solve the proposed optimization problem. Monte Carlo studies are evaluated the finite-sample performance of the proposed methods. The results indicate that the finite sample performance of the proposed methods performs better than that of the existing methods when there are leverage points or outliers in the response variable or explanatory variables. Finally, we apply the proposed methodology to analyze two real datasets.     

Testing for bioequivalence of highly variable drugs from TR‐RT crossover designs with heterogeneous residual variances

Traditional bioavailability studies assess average bioequivalence (ABE) between the test (T) and reference (R) products under the crossover design with TR and RT sequences. With highly variable (HV) drugs whose intrasubject coefficient of variation in pharmacokinetic measures is 30% or greater, assertion of ABE becomes difficult due to the large sample sizes needed to achieve adequate power. In 2011, the FDA adopted a more relaxed, yet complex, ABE criterion and supplied a procedure to assess this criterion exclusively under TRR‐RTR‐RRT and TRTR‐RTRT designs. However, designs with more than 2 periods are not always feasible. This present work investigates how to evaluate HV drugs under TR‐RT designs. A mixed model with heterogeneous residual variances is used to fit data from TR‐RT designs. Under the assumption of zero subject‐by‐formulation interaction, this basic model is comparable to the FDA‐recommended model for TRR‐RTR‐RRT and TRTR‐RTRT designs, suggesting the conceptual plausibility of our approach. To overcome the distributional dependency among summary statistics of model parameters, we develop statistical tests via the generalized pivotal quantity (GPQ). A real‐world data example is given to illustrate the utility of the resulting procedures. Our simulation study identifies a GPQ‐based testing procedure that evaluates HV drugs under practical TR‐RT designs with desirable type I error rate and reasonable power. In comparison to the FDA's approach, this GPQ‐based procedure gives similar performance when the product's intersubject standard deviation is low (≤0.4) and is most useful when practical considerations restrict the crossover design to 2 periods.     

“五四”精神的内在本质和现代传承

“五四”精神由两个层面的内容构成。第一层面是“五四”精神的内在本质,主要由“五四”精神的核心点与精髓构成;第二层面是“五四”精神的外在表现形式,主要包括不怕困难顽强斗争的精神、改革创新的精神、与为民精神等。在全面落实科学发展观、构建社会主义和谐社会的新的历史时期,应结合时代的变化,从“五四”精神的上述两个方面入手．切实发扬传承好这份宝贵的精神遗产。     

Confidence interval estimation of the difference between paired AUCs based on combined biomarkers

In many diagnostic studies, multiple diagnostic tests are performed on each subject or multiple disease markers are available. Commonly, the information should be combined to improve the diagnostic accuracy. We consider the problem of comparing the discriminatory abilities between two groups of biomarkers. Specifically, this article focuses on confidence interval estimation of the difference between paired AUCs based on optimally combined markers under the assumption of multivariate normality. Simulation studies demonstrate that the proposed generalized variable approach provides confidence intervals with satisfying coverage probabilities at finite sample sizes. The proposed method can also easily provide P-values for hypothesis testing. Application to analysis of a subset of data from a study on coronary heart disease illustrates the utility of the method in practice.     

五四新文化运动与中国文化传统三题

发端于五四时期的现代新儒家之基本价值倾向是主张现代化的,因而它亦应归于"五四新文化运动"的范畴,所谓"五四新文化运动是全盘反传统"的论断是不成立的。中国文化现代开展的内在逻辑体现为从"外在冲击"到"内在转化",五四新文化运动构成了这一过程的的转折点,虽然它的批判和否定曾经对中国文化传统造成了一定的冲击,但它没有也不可能造成中国文化传统的断裂。就中国文化现代开展的整体进程而言,中国文化精神之主体性的挺立是一个不断得到加强的过程,中国文化传统受到了越来越多的重视。五四新文化运动所开启的文化格局进一步充实和丰富了中国文化的生命力,为中国文化传统面向21世纪的新开展增添了新的生机与活力。     

Quantile regression for robust estimation and variable selection in partially linear varying-coefficient models

In this paper, we develop a new estimation procedure based on quantile regression for semiparametric partially linear varying-coefficient models. The proposed estimation approach is empirically shown to be much more efficient than the popular least squares estimation method for non-normal error distributions, and almost not lose any efficiency for normal errors. Asymptotic normalities of the proposed estimators for both the parametric and nonparametric parts are established. To achieve sparsity when there exist irrelevant variables in the model, two variable selection procedures based on adaptive penalty are developed to select important parametric covariates as well as significant nonparametric functions. Moreover, both these two variable selection procedures are demonstrated to enjoy the oracle property under some regularity conditions. Some Monte Carlo simulations are conducted to assess the finite sample performance of the proposed estimators, and a real-data example is used to illustrate the application of the proposed methods.     

On the estimation of a sensitive quantitative mean using blank cards

In this article, we introduce for the first time, the blank card methods for estimation of finite population mean of a sensitive variable. Two generic randomization devices are suggested, and for each device we identify the choices of special models. We introduce additive, multiplicative, and combination of both additive and multiplicative scrambling models that require use of a non sensitive variable. We derive the basic statistical properties of each model. It is interesting to note that various existing estimators can be viewed as the special cases of those presented here. The statistical efficiency of proposed techniques is compared with Greenberg et al. (1971 Greenberg, B.G., Kuebler Jr, R.R., Abernathy, J.R., Horvitz, D.G. (1971). Application of the randomized response technique in obtaining quantitative data. J. Am. Stat. Assoc. 66(334):243–250.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) and modified Perri (2008 Perri, P.F. (2008). Modified randomized devices for Simmons’ model. Model Assisted Stat. Appl. 3(3):233–239. [Google Scholar]) model. The proposed devices can easily be adjusted to achieve the required efficiency level by making suitable choices of different design parameters.