基于随机化回答模型的最低工资敏感性问题研究

针对最低工资调查中出现的敏感性问题,引入随机化回答技术,并针对定性和定量两类敏感性问题,分别引入不同的随机化回答模型。同时还考虑到最低工资调查中,不同调查单位对同一问题敏感程度不相同的特性,在定量问题的随机化回答模型中引入敏感性水平,对原有模型进行有效的改进,使被调查者能够更加积极配合最低工资调查,从而能够进一步减少由于各类敏感性问题造成的非抽样误差。这套随机化处理方法还可推广应用到其他类型的敏感性问题中。     

Prediction of accrual closure date in multi-center clinical trials with discrete-time Poisson process models

In a phase III multi‐center cancer clinical trial or a large public health study, sample size is predetermined to achieve desired power, and study participants are enrolled from tens or hundreds of participating institutions. As the accrual is closing to the target size, the coordinating data center needs to project the accrual closure date on the basis of the observed accrual pattern and notify the participating sites several weeks in advance. In the past, projections were simply based on some crude assessment, and conservative measures were incorporated in order to achieve the target accrual size. This approach often resulted in excessive accrual size and subsequently unnecessary financial burden on the study sponsors. Here we proposed a discrete‐time Poisson process‐based method to estimate the accrual rate at time of projection and subsequently the trial closure date. To ensure that target size would be reached with high confidence, we also proposed a conservative method for the closure date projection. The proposed method was illustrated through the analysis of the accrual data of the National Surgical Adjuvant Breast and Bowel Project trial B‐38. The results showed that application of the proposed method could help to save considerable amount of expenditure in patient management without compromising the accrual goal in multi‐center clinical trials. Copyright © 2012 John Wiley & Sons, Ltd.     

Seven useful designs

When designing a clinical trial there is a need to design a study that achieves the objectives of a trial both efficiently and with minimum resources. This paper describes seven trial designs that could possibly be used in clinical development and highlights how a design although not optimal for an individual study may be optimal for a wider clinical program.     

基于企业学习策略的集群持续创新机制及实证研究

由于集群网络的复杂性,集群创新机制的研究目前较为缺乏,有限的研究也往往假设集群企业具有同质性.本文提出,集群企业依据其在集群网络中的位置采用不同的学习策略,领导型企业更加侧重于探索式学习,跟随型企业更加侧重于利用式学习,两者的分工和异质性互动构成了集群持续创新的内在机理.本文在个体和企业层次双重学习研究的基础上,结合集群特有的组织条件,提出集群双重学习的机制,据此将集群企业进行分类,并建立集群中企业学习的理论模型,接着选取国内某地化工产业集群的236家企业作为样本,运用结构方程模型对集群中企业进行分类检验和比较研究.研究结果表明,集群中不同类型企业的学习策略存在差异,集群网络的作用是产生这一差异的可能原因;集群中不同类型企业的学习策略具有互补性,有利于企业间互动和集群的持续创新.     

均势原则的伦理辩护

均势原则是随机临床试验的基本原则,但也遭到了一些质疑。质疑者认为,均势原则预设了研究者的治疗性义务,限制了随机临床试验的发展,因此应当取消均势原则。其实,这些质疑并没有发展性地理解均势原则,质疑本身也充满了矛盾。我们尝试从伦理学的角度对均势原则进行辩护。     

Abstracts of theses,July 1955: Smith College School for Social Work

Abstract

This commentary amplifies the dynamic strategies in Message in a Bottleto consider in working with clients who seek to augment psychotherapy with psychopharmacologic treatment. This commentary also addresses how to evaluate and enhance psychotherapy outcome independent of medications and reviews some of the factors which contribute to positive treatment outcome. In order for clinicians to resist the pervasive colonizing effects of the medical model, this commentary reevaluates some of the claims that medications seem to promise and reinforces data which demonstrate that psychotherapy remains a safe and effective first-line treatment.     

Research ethics and clinical trials: Fostering collaboration with research participants

Accountability in research is a concept that applies to researchers and study participants alike. Human subjects play an active part in the success or failure of a clinical trial by virtue of their understanding of a study's goals expectations of personal gain, and adherence to study design. Trials must be designed to address patient concerns, offer an improved consent process, and move beyond our narrow conception of “patient rights.”; Problems with protocol adherence may be reduced by conceptualizing clinical research as an endeavor with mutual accountability within a relational ethic.     

中国人口现代化水平区域分布差异的主成分聚类分析

本文主要根据2000年全国第五次人口普查资料,首先选用了11个人口、国民经济和社会发展指标组成人口现代化指标体系。然后,通过SPSS统计分析软件进行主成分分析,选取三个主成分,分别用以反映各省市区人口现代化发展水平在人口结构与生活质量、生育模式与人口素质等三个方面的差异,最后通过聚类分析,将全国各省市人口现代化水平分为四种类型,并分析了四个类型各自的特征与差别及在空间上的区域差异。     

文化遗产国际司法保护的里程碑

探讨纽伦堡审判对于文化遗产国际司法保护的历史意义。简单交代纽伦堡审判的背景,详细叙述纽伦堡审判中关于破坏文化遗产罪行的起诉书和判决书的内容,指出其依据在于1907年《海牙公约》和长期以来形成的国际习惯法规范。纽伦堡审判中所形成的一系列原则对于制止破坏文化遗产的罪行、推动文化遗产保护规则的法典化都有重要意义。     

问卷设计中敏感性问题的处理

针对目前市场调查中敏感性问题的研究现状,提出从问卷设计角度来进行敏感性问题的处理,得到了敏感性问题的两种处理办法：非数学化的处理和数学化的处理——随机回答技术。实践表明,这两种方法能更好地提高调查质量。