Generalized Estimation of the BLUP in Mixed-Effects Models: A Comparison with ML and REML

The Best Linear Unbiased Predictor (BLUP) in mixed models is a function of the variance components and they are estimated using maximum likelihood (ML) or restricted ML methods. Nonconvergence of BLUP would occur due to a drawback of the standard likelihood-based approaches. In such situations, ML and REML either do not provide any BLUPs or all become equal. To overcome this drawback, we provide a generalized estimate (GE) of BLUP that does not suffer from the problem of negative or zero variance components, and compare its performance against the ML and REML estimates of BLUP. Simulated and published data are used to compare BLUP.     

基于 JCR 的不同学科类目文献计量学指标的统计与分析

基于2011年JCR网络版,对JCR所划分的176个学科类目的文献计量学指标,包括总被引频次、中值影响因子、学科集合影响因子、学科集合立即指数、学科集合被引半衰期、学科期刊数和学科总文章数,进行了统计与分析.结果表明：不同学科类目计量指标差异很大.建议在学术期刊评比和科研绩效评价时,应使用相对指标来消除学科之间的差异.     

Asymptotic Inference on Cointegrating Rank in Partial Systems

The likelihood ratio test for cointegrating rank is analyzed for partial (or conditional) systems in the vector autoregressive error-correction model. Under the assumption of weak exogeneity for the cointegrating parameters, the asymptotic distributions are given and tables of critical values are provided. A discussion is given of some of the assumptions of the model, why they are needed, and how they are tested.     

Semiparametric median residual life model and inference

For randomly censored data, the authors propose a general class of semiparametric median residual life models. They incorporate covariates in a generalized linear form while leaving the baseline median residual life function completely unspecified. Despite the non‐identifiability of the survival function for a given median residual life function, a simple and natural procedure is proposed to estimate the regression parameters and the baseline median residual life function. The authors derive the asymptotic properties for the estimators, and demonstrate the numerical performance of the proposed method through simulation studies. The median residual life model can be easily generalized to model other quantiles, and the estimation method can also be applied to the mean residual life model. The Canadian Journal of Statistics 38: 665–679; 2010 © 2010 Statistical Society of Canada     

The mad estimator: when is it non-linear? applications to two-way design models

The mean absolute deviation (MAD) estimator has recently received a great deal of attention as applied to full-rank linear regression models. This paper provides a necessary and sufficient condition for the MAD estimator to be a non-linear estimator, in which case conditions for the variance of the MAD estimator to be larger or smaller than those for OLS are, in general, unknown. The non-linearity of the MAD estimator is examined for several two-way designs; in particular (1) randomized block design (2) two-way nested design (3) two-way classification with interaction and (4) partially balanced incomplete block design     

A class of semiparametric transormation frailty models with application to estimating treatment effects and heterogenity in aids clinical traials

Muitivariate failure time data are common in medical research; com¬monly used statistical models for such correlated failure-time data include frailty and marginal models. Both types of models most often assume pro¬portional hazards (Cox, 1972); but the Cox model may not fit the data well This article presents a class of linear transformation frailty models that in¬cludes, as a special case, the proportional hazards model with frailty. We then propose approximate procedures to derive the best linear unbiased es¬timates and predictors of the regression parameters and frailties. We apply the proposed methods to analyze results of a clinical trial of different dose levels of didansine (ddl) among HIV-infected patients who were intolerant of zidovudine (ZDV). These methods yield estimates of treatment effects and of frailties corresponding to patient groups defined by clinical history prior to entry into the trial.     

Asymptotic equivalence of the harrell-davis median estimator and the sample median

This paper presents an asymptotic equivalence result with a sharp rate of convergence forthe sample median and the Harrell-Davis median estimator. The consequences of this result are discussed.     

Hierarchical Variable Selection in Polynomial Regression Models

Significance tests on coefficients of lower-order terms in polynomial regression models are affected by linear transformations. For this reason, a polynomial regression model that excludes hierarchically inferior predictors (i.e., lower-order terms) is considered to be not well formulated. Existing variable-selection algorithms do not take into account the hierarchy of predictors and often select as “best” a model that is not hierarchically well formulated. This article proposes a theory of the hierarchical ordering of the predictors of an arbitrary polynomial regression model in m variables, where m is any arbitrary positive integer. Ways of modifying existing algorithms to restrict their search to well-formulated models are suggested. An algorithm that generates all possible well-formulated models is presented.     

Analysis of a factorial quantal response assay using inverse regression

An inverse regression approach to analyzing quantal response assays with one quanritative independent- variable and any number of qualitative independent variables is presented. A general factorial model ror LQC- inverted relationship and methods of testing hypotheses estimating qulitative Interest are developed. This naper provides a modified method of analysis which is easier to apply than previously existing methods.     

Splines for financial volatility

Summary.  We propose a flexible generalized auto-regressive conditional heteroscedasticity type of model for the prediction of volatility in financial time series. The approach relies on the idea of using multivariate B -splines of lagged observations and volatilities. Estimation of such a B -spline basis expansion is constructed within the likelihood framework for non-Gaussian observations. As the dimension of the B -spline basis is large, i.e. many parameters, we use regularized and sparse model fitting with a boosting algorithm. Our method is computationally attractive and feasible for large dimensions. We demonstrate its strong predictive potential for financial volatility on simulated and real data, and also in comparison with other approaches, and we present some supporting asymptotic arguments.