Statistical inference for the difference of two Lorenz curves

Testing the Lorenz dominance is of importance in economic and social sciences. In this article, we propose new tools to do inferences for the difference of two Lorenz curves. The asymptotic normality of the proposed smoothed nonparametric estimator is proved. We also propose a smoothed jackknife empirical likelihood (JEL) method which avoids to estimate the complicate asymptotic variance. It is proved that the proposed JEL ratio statistics converge to the standard chi-square distribution. Simulation studies and real data analysis are also conducted, and show encouraging finite-sample performance.     

Critical review and comparison of continuity correction methods: The normal approximation to the binomial distribution

We provide a comprehensive and critical review of Yates’ continuity correction for the normal approximation to the binomial distribution, in particular emphasizing its poor ability to approximate extreme tail probabilities. As an alternative method, we also review Cressie's finely tuned continuity correction. In addition, we demonstrate how Yates’ continuity correction is used to improve the coverage probability of binomial confidence limits, and propose new confidence limits by applying Cressie's continuity correction. These continuity correction methods are numerically compared and illustrated by data examples arising from industry and medicine.     

Minimum Volume Confidence Sets for Two-Parameter Exponential Distributions

Under a reasonable restriction, we create the minimum volume confidence set for location and scale parameters of the exponential distribution. Compared to existing methods, none of which has a minimum-area property, the new confidence set is significantly the best (most accurate) with smallest volume, for whatever confidence level, sample size, and sample data.     

Invariance,Optimality, and a 1-Observation Confidence Interval for a Normal Mean

In a 1965 Decision Theory course at Stanford University, Charles Stein began a digression with “an amusing problem”: is there a proper confidence interval for the mean based on a single observation from a normal distribution with both mean and variance unknown? Stein introduced the interval with endpoints ± c|X| and showed indeed that for c large enough, the minimum coverage probability (over all values for the mean and variance) could be made arbitrarily near one. While the problem and coverage calculation were in the author’s hand-written notes from the course, there was no development of any optimality result for the interval. Here, the Hunt–Stein construction plus analysis based on special features of the problem provides a “minimax” rule in the sense that it minimizes the maximum expected length among all procedures with fixed coverage (or, equivalently, maximizes the minimal coverage among all procedures with a fixed expected length). The minimax rule is a mixture of two confidence procedures that are equivariant under scale and sign changes, and are uniformly better than the classroom example or the natural interval X ± c|X|?.     

Generalized Empirical Likelihood Inference in Generalized Linear Models for Longitudinal Data

In this article, the generalized linear model for longitudinal data is studied. A generalized empirical likelihood method is proposed by combining generalized estimating equations and quadratic inference functions based on the working correlation matrix. It is proved that the proposed generalized empirical likelihood ratios are asymptotically chi-squared under some suitable conditions, and hence it can be used to construct the confidence regions of the parameters. In addition, the maximum empirical likelihood estimates of parameters are obtained, and their asymptotic normalities are proved. Some simulations are undertaken to compare the generalized empirical likelihood and normal approximation-based method in terms of coverage accuracies and average areas/lengths of confidence regions/intervals. An example of a real data is used for illustrating our methods.     

Confidence intervals for parameters lying in a random polygon

This paper presents algorithms for computing confidence intervals and regions for elements of a parameter vector when the signs of linear combinations of unknown parameters are observed, but the coefficients contain experimental error. These methods were proposed in the geochemical literature by Kolassa (1992) as a method specific to petrology. Experimental data are used to give linear constraints, involving quantities measured with error, on unknown free energies and entropies of a chemical reaction. Confidence intervals are given for these parameters, and these are compared with more naïve approaches.     

An Optimal Confidence Region for the Largest and the Smallest Means from a Multivariate Normal Distribution

An optimal confidence region is proposed for obtaining the largest and the smallest means of a multivariate normal distribution with a common unknown variance and a non-negative correlation coefficient. The confidence region is compared to a class of asymmetric confidence regions, and the results show that it is uniformly better. Further, a design-oriented two-stage confidence region with a fixed width is also given. Finally, the optimal confidence region is applied to an experiment to measure the treatment effectiveness of a physical therapy with four independent groups and the result reveals that the proposed confidence region can provide some useful information.     

Interval Estimations for the Mean of the Generalized Poisson and Generalized Negative Binomial Distributions

In this article, we extend the Wald, score, skewness-corrected score, likelihood ratio, and mid-P intervals for the means of the generalized Poisson and generalized negative binomial distributions. These distributions are the members of the discrete version of the natural exponential family (NEF) with cubic variance function (CVF). Also, the coverage probabilities, the distal and mesial noncoverage probabilities, and the lengths of the proposed confidence intervals are estimated by means of a Monte Carlo simulation study. Finally, some practical examples are provided to show the applicability of the proposed intervals in applied studies.     

Two-sample high-dimensional empirical likelihood

In this paper, we apply empirical likelihood for two-sample problems with growing high dimensionality. Our results are demonstrated for constructing confidence regions for the difference of the means of two p-dimensional samples and the difference in value between coefficients of two p-dimensional sample linear model. We show that empirical likelihood based estimator has the efficient property. That is, as p → ∞ for high-dimensional data, the limit distribution of the EL ratio statistic for the difference of the means of two samples and the difference in value between coefficients of two-sample linear model is asymptotic normal distribution. Furthermore, empirical likelihood (EL) gives efficient estimator for regression coefficients in linear models, and can be as efficient as a parametric approach. The performance of the proposed method is illustrated via numerical simulations.     

On difference factor in assessment of dissolution similarity

In vitro dissolution similarity has been suggested as a surrogate for assessing equivalence between the pre-changed and post-changed formulations for postapproval changes of a drug. The difference factor f₁, based on the absolute mean difference, has been proposed as a criterion for evaluating similarity between dissolution profiles. Statistical properties including density function, bias, and asymptotic distribution of a consistent estimator are investigated. Due to complexity of the distribution of the estimator, we suggest the use of the confidence intervals obtained from the bootstrap method for evaluation of dissolution similarity. A simulation was conducted to examine the size and power of the proposed CI procedure. Comparisons with other criteria such as similarity factor are also provided. Numerical examples are used to illustrate the proposed CI procedure.