Reliability estimation in stress–strength models: an MCMC approach

In this paper, we consider the estimation of the stress–strength parameter R=P(Y<X) when X and Y are independent and both are modified Weibull distributions with the common two shape parameters but different scale parameters. The Markov Chain Monte Carlo sampling method is used for posterior inference of the reliability of the stress–strength model. The maximum-likelihood estimator of R and its asymptotic distribution are obtained. Based on the asymptotic distribution, the confidence interval of R can be obtained using the delta method. We also propose a bootstrap confidence interval of R. The Bayesian estimators with balanced loss function, using informative and non-informative priors, are derived. Different methods and the corresponding confidence intervals are compared using Monte Carlo simulations.     

Non-linear models 1

This is the first application of a new method for testing stationary random point processes. Consider the class of all stationary ergodic point processes on the real line with arbitrary dependences among the inter–point distances (spacing).The hypothesis is :The observed process φ is a homogeneous Poisson process or more (resp.less) regular than a Poisson process.The sample is the vector of the first n points t₁, …,t_n.There is a close relation between our method for testing and queueing theory: For finding an appropriate test statistic, we observe the behaviour of a single server queue with the input φ.A table of critical values is given.     

Exact Likelihood Equations for Autoregression Models with Multivariate Elliptically Contoured Distributions

Abstract

The multivariate elliptically contoured distributions provide a viable framework for modeling time-series data. It includes the multivariate normal, power exponential, t, and Cauchy distributions as special cases. For multivariate elliptically contoured autoregressive models, we derive the exact likelihood equations for the model parameters. They are closely related to the Yule-Walker equations and involve simple function of the data. The maximum likelihood estimators are obtained by alternately solving two linear systems and illustrated using the simulation data.     

Testing Equality of Mean Vectors in Two Sample Problem with Missing Data

Finding the influence of traffic accident on the road is helpful to analyze the characteristics of traffic flow, and take reasonable and effective control measures. Here, the detrended fluctuation analysis method is applied to investigate the complexity of time series in mixed traffic flow with a blockage induced by an accident. As a parameter to depict the long-term evolutionary behavior of the time series in traffic flow, the scaling exponent is analyzed. According to the scaling exponent, it is shown that the traffic flow time series can display long-range correlation characteristics, short-range correlation characteristics, and non-power-law relation in the long-range correlation characteristics, which is strongly dependent on the entering probability of vehicle, the ratio of slow vehicle and the blockage duration time.     

Dirichlet Processes in Nonlinear Mixed Effects Models

In this article, we use two efficient approaches to deal with the difficulty in computing the intractable integrals when implementing Gibbs sampling in the nonlinear mixed effects model (NLMM) based on Dirichlet processes (DP). In the first approach, we compute the Laplace's approximation to the integral for its high accuracy, low cost, and ease of implementation. The second approach uses the no-gaps algorithm of MacEachern and Müller (1998 MacEachern , S. , Müller , P. ( 1998 ). Estimating mixtures of Dirichlet process models . Journal of Computational and Graphical Statistics 7 : 223 – 238 .[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]) to perform Gibbs sampling without evaluating the difficult integral. We apply both approaches to real problems and simulations. Results show that both approaches perform well in density estimation and prediction and are superior to the parametric analysis in that they can detect important model features, such as skewness, long tails, and multimodality, whereas the parametric analysis cannot.     

Infinite Variation Tempered Stable Ornstein–Uhlenbeck Processes with Discrete Observations

We investigate transition law between consecutive observations of Ornstein–Uhlenbeck processes of infinite variation with tempered stable stationary distribution. Thanks to the Markov autoregressive structure, the transition law can be written in the exact sense as a convolution of three random components; a compound Poisson distribution and two independent tempered stable distributions, one with stability index in (0, 1) and the other with index in (1, 2). We discuss simulation techniques for those three random elements. With the exact transition law and proposed simulation techniques, sample paths simulation proves significantly more efficient, relative to the known approximative technique based on infinite shot noise series representation of tempered stable Lévy processes.     

Dependence Between Two Diagnostic Tests with Copula Function Approach: A Simulation Study

The study of the dependence between two medical diagnostic tests is an important issue in health research since it can modify the diagnosis and, therefore, the decision regarding a therapeutic treatment for an individual. In many practical situations, the diagnostic procedure includes the use of two tests, with outcomes on a continuous scale. For final classification, usually there is an additional “gold standard” or reference test. Considering binary test responses, we usually assume independence between tests or a joint binary structure for dependence. In this article, we introduce a simulation study assuming two dependent dichotomized tests using two copula function dependence structures in the presence or absence of verification bias. We compare the test parameter estimators obtained under copula structure dependence with those obtained assuming binary dependence or assuming independent tests.     

Case–control genome-wide joint association study using semiparametric empirical model and approximate Bayes factor

We propose a semiparametric approach for the analysis of case–control genome-wide association study. Parametric components are used to model both the conditional distribution of the case status given the covariates and the distribution of genotype counts, whereas the distribution of the covariates are modelled nonparametrically. This yields a direct and joint modelling of the case status, covariates and genotype counts, and gives a better understanding of the disease mechanism and results in more reliable conclusions. Side information, such as the disease prevalence, can be conveniently incorporated into the model by an empirical likelihood approach and leads to more efficient estimates and a powerful test in the detection of disease-associated SNPs. Profiling is used to eliminate a nuisance nonparametric component, and the resulting profile empirical likelihood estimates are shown to be consistent and asymptotically normal. For the hypothesis test on disease association, we apply the approximate Bayes factor (ABF) which is computationally simple and most desirable in genome-wide association studies where hundreds of thousands to a million genetic markers are tested. We treat the approximate Bayes factor as a hybrid Bayes factor which replaces the full data by the maximum likelihood estimates of the parameters of interest in the full model and derive it under a general setting. The deviation from Hardy–Weinberg Equilibrium (HWE) is also taken into account and the ABF for HWE using cases is shown to provide evidence of association between a disease and a genetic marker. Simulation studies and an application are further provided to illustrate the utility of the proposed methodology.     

General treatment of goodness-of-fit tests based on Kullback–Leibler information

This paper introduces a general goodness-of-fit test based on the estimated Kullback–Leibler information. The test uses the Vasicek entropy estimate. Two special cases of the test for location–scale and shape families are discussed. The results are used to introduce goodness-of-fit tests for the uniform, Laplace, Weibull and beta distributions. The critical values and powers for some alternatives are obtained by simulation.     

Semiparametric inference for open populations using the Jolly–Seber model: a penalized spline approach

When there are frequent capture occasions, both semiparametric and nonparametric estimators for the size of an open population have been proposed using kernel smoothing methods. While kernel smoothing methods are mathematically tractable, fitting them to data is computationally intensive. Here, we use smoothing splines in the form of P-splines to provide an alternate less computationally intensive method of fitting these models to capture–recapture data from open populations with frequent capture occasions. We fit the model to capture data collected over 64 occasions and model the population size as a function of time, seasonal effects and an environmental covariate. A small simulation study is also conducted to examine the performance of the estimators and their standard errors.