Some sampling effects of pairwise correlated observations on likelihood ratio tests for the difference between two means

We study the effects of the inclusion of pairs of correlated observations in a sample on likelihood ratio tests for the difference in two means. In particular, we assess how the inclusion of correlated data pairs (e.g., such as data inadvertently collected from sib-pairs) affects the sample size requirements necessary for the implementation of a Likelihood Ratio (LR) test for the difference between two means. Our results suggest that correlated data pairs beneficially or adversely effect sample size requirements for an LR test to a degree functionally related to the mixture parameters dictating their relative frequencies in the larger sample on which the test will be performed, the strength of the correlation between the observations, and the size of imbalances in the sample with respect to the number of observations in each group. The relevance and implications of the results for genetic and epidemiologic research are discussed.     

Maximum likelihood estimation,from doubly censored samples,of the mean of a normal distribution with known coeffucient of variation

Let x be a random variable having the normal distribution with mean μ and variance c²μ², where c is a known constant. The maximum likelihood estimation of μ when the lowest r₁ and the highest r₂ sample values censored have been given the asymptotic variance of the maximum likelihood estimator is obtained.     

The mean of linear signed rank statistics under alternatives

An expression is presented for the mean of a linear signed rank statistic for the one sample location model. Several examples are given to illustrate its application.     

Nonparametric estimation of the survival distribution in censored data

Two nonparametric estimators o f the survival distributionare discussed. The estimators were proposed by Kaplan and Meier (1958) and Breslow (1972) and are applicable when dealing with censored data. It is known that they are asymptotically unbiased and uniformly strongly consistent, and when properly normalized that they converge weakly to the same Gaussian process. In this paper, the properties of the estimators are carefully inspected in small or moderate samples. The Breslow estimator, a shrinkage version of the Kaplan-Meier, nearly always has the smaller mean square error (MSE) whenever the truesurvival probabilityis at least 0.20, but has considerably larger MSE than the Kaplan-Meier estimator when the survivalprobability is near zero.     

Fisher Information in Type II Progressive Censored Samples

Recently, progressively Type II censored samples have attracted attention in the study and analysis of life-testing data. Here we propose an indirect approach for computing the Fisher information (FI) in progressively Type II censored samples that simplifies the calculations. Some recurrence relations for the FI in progressively Type II censored samples are derived that facilitate the FI computation using the proposed decomposition. This paper presents a standard recurrence relation that simplifies computation of the FI in progressively Type II censored samples to a sum; FI in collections order statistics (OS). We compute the FI in a collections of progressively Type II censored samples for some known distributions.     

On tail-ordering and comparison of failure rates

In this paper, we have studied some implications between tail-ordering (also known as dispersive ordering) and failure rate ordering (also called TP₂ ordering) of two probability distribution functions. Based on independent random samples from these distributions, a class of distribution-free tests has been proposed for testing the null hypothesis that the two life distributions are identical against the alternative that one failure rate is uniformly smaller than the other. The tests have good efficiencies as compared to their competitors.     

Anderson's classification statistic based on a post-stratified training sample

The performance of Anderson's classification statistic based on a post-stratified random sample is examined. It is assumed that the training sample is a random sample from a stratified population consisting of two strata with unknown stratum weights. The sample is first segregated into the two strata by post-stratification. The unknown parameters for each of the two populations are then estimated and used in the construction of the plug-in discriminant. Under this procedure, it is shown that additional estimation of the stratum weight will not seriously affect the performance of Anderson's classification statistic. Furthermore, our discriminant enjoys a much higher efficiency than the procedure based on an unclassified sample from a mixture of normals investigated by Ganesalingam and McLachlan (1978).     

Computational and statistical efficiency of semiparametric gls estimators

In this note, we report a dramatic improvement in the computational efficiency of semiparametric generalized least squares(SGLS) estimation. Computation of SGLS estimates no longer presents serious problems with data sets of moderate size. We also correct a numerical error in the standard errors of the SGLS estimates reported in our recent paper in this journal (Horowitz and Neumann, 1987). The corrected standard errors of SGLS are comparable to those we reported for quantile estimates.     

A note on the satterthwaite confidence interval for a variance

When using a Satterthwaite chi-squared approximation, it is generally thought that the approximation is satisfactory when it is applied to a positive linear combination of mean squares. In this note, we describe how the Williams - Tukey idea for getting a confidence interval for the among groups variance in a random one-way model can be incorporated into Satterthwaite’s procedure for getting a confidence interval for a variance. This adjusted Satterthwaite procedure insures that his chi-squared approximation is always applied to positive linear combinations of mean squares. A small simulation is included which suggests that the adjustment to the Satterthwaite procedure is effective.