Profile upper Confidence Limits from Discrete Data

When the data are discrete, standard approximate confidence limits often have coverage well below nominal for some parameter values. While ad hoc adjustments may largely solve this problem for particular cases, Kabaila & Lloyd (1997) gave a more systematic method of adjustment which leads to tight upper limits, which have coverage which is never below nominal and are as small as possible within a particular class. However, their computation for all but the simplest models is infeasible. This paper suggests modifying tight upper limits by an initial replacement of the unknown nuisance parameter vector by its profile maximum likelihood estimator. While the resulting limits no longer possess the optimal properties of tight limits exactly, the paper presents both numerical and theoretical evidence that the resulting coverage function is close to optimal. Moreover these profile upper limits are much (possibly many orders of magnitude) easier to compute than tight upper limits.     

STEIN'S METHOD AND THE BERRY-ESSÉEN THEOREM

Stein's method is used to prove the Lindeberg-Feller theorem and a generalization of the Berry-Esséen theorem. The arguments involve only manipulation of probability inequalities, and form an attractive alternative to the less direct Fourier-analytic methods which are traditionally employed.     

极限证明初探

本文结合教学中正反两方面的例子,从理论上较深入地讨论了如何理解极限定义和掌握极限证明的方法,并回答了证明中可能出现的问题.     

Model-based confidence bands for survival functions

This paper focuses on a novel method of developing one-sample confidence bands for survival functions from right censored data. The approach is model-based, relying on a parametric model for the conditional expectation of the censoring indicator given the observed minimum, and derives its strength from easy access to a good-fitting model among a plethora of choices available for binary response data. The substantive methodological contribution is in exploiting a semiparametric estimator of the survival function to produce improved simultaneous confidence bands. To obtain critical values for computing the confidence bands, a two-stage bootstrap approach that combines the classical bootstrap with the more recent model-based regeneration of censoring indicators is proposed and a justification of its asymptotic validity is also provided. Several different confidence bands are studied using the proposed approach. Numerical studies, including robustness of the proposed bands to misspecification, are carried out to check efficacy. The method is illustrated using two lung cancer data sets.     

Testing for a change in covariance operator

The paper considers a problem of equality of two covariance operators. Using functional principal component analysis, a method for testing equality of K largest eigenvalues and the corresponding eigenfunctions, together with its generalization to a corresponding change point problem is suggested. Asymptotic distributions of the test statistics are presented.     

Multivariate Kendall's tau for change‐point detection in copulas

Statistical procedures for the detection of a change in the dependence structure of a series of multivariate observations are studied in this work. The test statistics that are proposed are $L_1$ , $L_2$ , and $L_{\infty }$ distances computed from vectors of differences of Kendall's tau; two multivariate extensions of Kendall's measure of association are used. Since the distributions of these statistics under the null hypothesis of no change depend on the unknown underlying copula of the vectors, a procedure based on the multiplier central limit theorem is used for the computation of p‐values; the method is shown to be valid both asymptotically and for moderate sample sizes. Alternative versions of the tests that take into account possible breakpoints in the marginal distributions are also investigated. Monte Carlo simulations show that the tests are powerful under many scenarios of change‐point. In addition, two estimators of the time of change are proposed and their efficiency is carefully studied. The methodologies are illustrated on simulated series from the Canadian Regional Climate Model. The Canadian Journal of Statistics 41: 65–82; 2013 © 2012 Statistical Society of Canada     

A comparison of test statistics for the recovery of rapid growth‐based enumeration tests

This paper considers five test statistics for comparing the recovery of a rapid growth‐based enumeration test with respect to the compendial microbiological method using a specific nonserial dilution experiment. The finite sample distributions of these test statistics are unknown, because they are functions of correlated count data. A simulation study is conducted to investigate the type I and type II error rates. For a balanced experimental design, the likelihood ratio test and the main effects analysis of variance (ANOVA) test for microbiological methods demonstrated nominal values for the type I error rate and provided the highest power compared with a test on weighted averages and two other ANOVA tests. The likelihood ratio test is preferred because it can also be used for unbalanced designs. It is demonstrated that an increase in power can only be achieved by an increase in the spiked number of organisms used in the experiment. The power is surprisingly not affected by the number of dilutions or the number of test samples. A real case study is provided to illustrate the theory. Copyright © 2013 John Wiley & Sons, Ltd.     

Functional sliced inverse regression analysis

Most of the usual multivariate methods have been extended to the context of functional data analysis. Our contribution concerns the study of sliced inverse regression (SIR) when the response variable is real but the regressor is a function. In the first part, we show how the relevant properties of SIR remain essentially the same in the functional context under suitable conditions. Unfortunately, the estimation procedure used in the multivariate case cannot be directly transposed to the functional one. Then, we propose a solution that overcomes this difficulty and we show the consistency of the estimates of the parameters of the model.     

INFLUENCE FUNCTIONS IN FUNCTIONAL MEASUREMENT ERROR MODELS WITH REPLICATED DATA

We consider the construction and properties of influence functions in the context of functional measurement error models with replicated data. In these models estimates of the parameters can be affected both by the individual observations and the means of replicated observations. We show that influence function of the means of replicates on the estimate of regression coefficients can be only derived under the assumption that the variances of the errors are known, while one for the individual observations can be only derived simultaneously with their influence function on the estimators of the variances of the errors.