Local predictive influence in bayesian linear models with conjugate priors

Cook (1986) presented the idea of local influence to study the sensitivity of inferences to model assumptions:introduce a vector δ of perturbations to the model; choose a discrepancy function D to measure differences between the original inference and the inference under the perturbed model; study the behavior of D near δ = 0, the original model, usually by taking derivatives. Johnson and Geisser (1983) measure influence in Bayesian inference by the Kullback-Leibler divergence between predictive distributions. I~IcCulloch (1989) is a synthesis of Cook and Johnson and Geisser, using Kullback-Leibler divergence between posterior or predictive distributions as the discrepancy function in Bayesian local influence analyses. We analyze a special case for which McCulloch gives the general theory; namely, the linear model with conjugate prior. We present specific formulae for local influence measures for 1) changes in the parameters of the gamma prior for the precision, 2) changes in the mean of the normal prior for the regression coefficients, 3) changes in the covariance matrix of the normal prior for the regression coefficients and 4) changes in the case weights. Our method is an easy way to find locally influential subsets of points without knowing in advance the sizes of the subsets. The techniques are illustrated with a regression example.     

Short run spc based upon the second order dynamic linear model for trend detection

Recently, several new applications of control chart procedures for short production runs have been introduced. Bothe (1989) and Burr (1989) proposed the use of control chart statistics which are obtained by scaling the quality characteristic by target values or process estimates of a location and scale parameter. The performance of these control charts can be significantly affected by the use of incorrect scaling parameters, resulting in either an excessive "false alarm rate," or insensitivity to the detection of moderate shifts in the process. To correct for these deficiencies, Quesenberry (1990, 1991) has developed the Q-Chart which is formed from running process estimates of the sample mean and variance. For the case where both the process mean and variance are unknown, the Q-chaxt statistic is formed from the standard inverse Z-transformation of a t-statistic. Q-charts do not perform correctly, however, in the presence of special cause disturbances at process startup. This has recently been supported by results published by Del Castillo and Montgomery (1992), who recommend the use of an alternative control chart procedure which is based upon a first-order adaptive Kalman filter model Consistent with the recommendations by Castillo and Montgomery, we propose an alternative short run control chart procedure which is based upon the second order dynamic linear model (DLM). The control chart is shown to be useful for the early detection of unwanted process trends. Model and control chart parameters are updated sequentially in a Bayesian estimation framework, providing the greatest degree of flexibility in the level of prior information which is incorporated into the model. The result is a weighted moving average control chart statistic which can be used to provide running estimates of process capability. The average run length performance of the control chart is compared to the optimal performance of the exponentially weighted moving average (EWMA) chart, as reported by Gan (1991). Using a simulation approach, the second order DLM control chart is shown to provide better overall performance than the EWMA for short production run applications     

The estimation of treatment effect for the censored bivariate data under the univariate censoring

This paper establishes a nonparametric estimator for the treatment effect on censored bivariate data under unvariate censoring. This proposed estimator is based on the one from Lin and Ying(1993)'s nonparametric bivariate survival function estimator, which is itself a generalized version of Park and Park(1995)' quantile estimator. A Bahadur type representation of quantile functions were obtained from the marginal survival distribution estimator of Lin and Ying' model. The asymptotic property of this estimator is shown below and the simulation studies are also given     

Influence analysis in multivariate linear general models

In this paper we obtain several influence measures for the multivariate linear general model through the approach proposed by Muñoz-Pichardo et al. (1995), which is based on the concept of conditional bias. An interesting charasteristic of this approach is that it does not require any distributional hypothesis. Appling the obtained results to the multivariate regression model, we obtain some measures proposed by other authors. Nevertheless, on the results obtained in this paper, we emphasize two aspects. First, they provide a theoretical foundation for measures proposed by other authors for the mul¬tivariate regression model. Second, they can be applied to any linear model that can be formulated as a particular case of the multivariate linear general model. In particular, we carry out an application to the multivariate analysis of covariance.     

A class of semiparametric transormation frailty models with application to estimating treatment effects and heterogenity in aids clinical traials

Muitivariate failure time data are common in medical research; com¬monly used statistical models for such correlated failure-time data include frailty and marginal models. Both types of models most often assume pro¬portional hazards (Cox, 1972); but the Cox model may not fit the data well This article presents a class of linear transformation frailty models that in¬cludes, as a special case, the proportional hazards model with frailty. We then propose approximate procedures to derive the best linear unbiased es¬timates and predictors of the regression parameters and frailties. We apply the proposed methods to analyze results of a clinical trial of different dose levels of didansine (ddl) among HIV-infected patients who were intolerant of zidovudine (ZDV). These methods yield estimates of treatment effects and of frailties corresponding to patient groups defined by clinical history prior to entry into the trial.     

Generalized additive mixed models

Following the extension from linear mixed models to additive mixed models, extension from generalized linear mixed models to generalized additive mixed models is made, Algorithms are developed to compute the MLE's of the nonlinear effects and the covariance structures based on the penalized marginal likelihood. Convergence of the algorithms and selection of the smooth param¬eters are discussed.     

Estimation of parameters of a pareto distribution by generalized order statistics

In this paper we address the problem of estimating the parameters of Pareto II distribution based on generalized order statistics. The estimators based on order statistics and record values are shown to be special cases of these estimators.     

Modified ridge analyses under nonstandard

A well-known procedure for the optimization of a second-degree response function over a spherical region of interest is that of ridge analysis. Khuri and Myers (1979) introduced a modification of this procedure by incorporating a certain constraint on the prediction variance. Both procedures, however, assume that the response variable has a constant variance throughtout the experimental region. In the present article, we consider two extensions to Khuri and Myers modifioed ridge analysis. The first extension relaxes the constant variance assumption. In the second extension. generalised linear models are used instead of the trasitional linear model. which are commenly used in responce variables that are not necessaily continusly distribution, including these have discreate distributions, Two examples are presented to illustrate the implementation of the proposed extensions.     

Multiple deletion measures and conditional influence in regression model

The joint effect of the deletion of the ith and jih cases is given by Gray and Ling (1984), they discussed the influence measures for influential subsets in linear regression analysis. The present paper is concerned with multiple sets of deletion measures in the linear regression model. In particular we are interested in the effects of the jointly and conditional influence analysis for the detection of two influential subsets.