A tool for systematically comparing the power of tests for normality

In this article, we describe a new approach to compare the power of different tests for normality. This approach provides the researcher with a practical tool for evaluating which test at their disposal is the most appropriate for their sampling problem. Using the Johnson systems of distribution, we estimate the power of a test for normality for any mean, variance, skewness, and kurtosis. Using this characterization and an innovative graphical representation, we validate our method by comparing three well-known tests for normality: the Pearson χ² test, the Kolmogorov–Smirnov test, and the D'Agostino–Pearson K ² test. We obtain such comparison for a broad range of skewness, kurtosis, and sample sizes. We demonstrate that the D'Agostino–Pearson test gives greater power than the others against most of the alternative distributions and at most sample sizes. We also find that the Pearson χ² test gives greater power than Kolmogorov–Smirnov against most of the alternative distributions for sample sizes between 18 and 330.     

Variable selection approach for zero-inflated count data via adaptive lasso

This article proposes a variable selection approach for zero-inflated count data analysis based on the adaptive lasso technique. Two models including the zero-inflated Poisson and the zero-inflated negative binomial are investigated. An efficient algorithm is used to minimize the penalized log-likelihood function in an approximate manner. Both the generalized cross-validation and Bayesian information criterion procedures are employed to determine the optimal tuning parameter, and a consistent sandwich formula of standard errors for nonzero estimates is given based on local quadratic approximation. We evaluate the performance of the proposed adaptive lasso approach through extensive simulation studies, and apply it to analyze real-life data about doctor visits.     

Lasso-type estimation for covariate-adjusted linear model

Lasso is popularly used for variable selection in recent years. In this paper, lasso-type penalty functions including lasso and adaptive lasso are employed in simultaneously variable selection and parameter estimation for covariate-adjusted linear model, where the predictors and response cannot be observed directly and distorted by some observable covariate through some unknown multiplicative smooth functions. Estimation procedures are proposed and some asymptotic properties are obtained under some mild conditions. It deserves noting that under appropriate conditions, the adaptive lasso estimator correctly select covariates with nonzero coefficients with probability converging to one and that the estimators of nonzero coefficients have the same asymptotic distribution that they would have if the zero coefficients were known in advance, i.e. the adaptive lasso estimator has the oracle property in the sense of Fan and Li [6]. Simulation studies are carried out to examine its performance in finite sample situations and the Boston Housing data is analyzed for illustration.     

The use of probabilistic models to produce optimal graphical displays of high-dimensional data sets

Summary Several techniques for exploring ann×p data set are considered in the light of the statistical framework: data-structure+noise. The first application is to Principal Component Analysis (PCA), in fact generalized PCA with any metric M on the unit space ℝ _p . A natural model for supporting this analysis is the fixed-effect model where the expectation of each unit is assumed to belong to some q-dimensional linear manyfold defining the structure, while the variance describes the noise. The best estimation of the structure is obtained for a proper choice of metric M and dimensionality q: guidelines are provided for both choices in section 2. The second application is to Projection Pursuit which aims to reveal structure in the original data by means of suitable low-dimensional projections of them. We suggest the use of generalized PCA with suitable metric M as a Projection Pursuit technique. According to the kind of structure which is looked for, two such metrics are proposed in section 3. Finally, the analysis ofn×p contingency tables is considered in section 4. Since the data are frequencies, we assume a multinomial or Poisson model for the noise. Several models may be considered for the structural part; we can say that Correspondence Analysis rests on one of them, spherical factor analysis on another one; Goodman association models also provide an alternative modelling. These different approaches are discussed and compared from several points of view.     

On the invariance of conditioning procedures for the specification of prior distributions for nested DAG models

Given a prior distribution for a model , the prior information specified on a nested submodel by means of a conditioning procedure crucially depends on the parameterisation used to describe the model. Regression coefficients represent the most common parameterisation of Gaussian DAG models. Nevertheless, in the specification of prior distributions, invariance considerations lead to the use of different parameterisations of the model, depending on the required invariance class. In this paper we consider the problem of prior specification by conditioning on zero regression coefficients and show that also such a procedure satisfies the property of invariance with respect to a class of parameterisations and characterise such a class.     

Bayesian generalized fused lasso modeling via NEG distribution

The fused lasso penalizes a loss function by the L₁ norm for both the regression coefficients and their successive differences to encourage sparsity of both. In this paper, we propose a Bayesian generalized fused lasso modeling based on a normal-exponential-gamma (NEG) prior distribution. The NEG prior is assumed into the difference of successive regression coefficients. The proposed method enables us to construct a more versatile sparse model than the ordinary fused lasso using a flexible regularization term. Simulation studies and real data analyses show that the proposed method has superior performance to the ordinary fused lasso.     

GENSI: A new graphical tool to collect ego-centered network data

This study (1) tested the effectiveness of a new survey tool to collect ego-centered network data and (2) assessed the impact of giving people feedback about their network on subsequent responses. The new tool, GENSI (Graphical Ego-centered Network Survey Interface), allows respondents to describe all network contacts at once via a graphical representation of their networks. In an online experiment, 434 American adults were randomly assigned to answer traditional network questions or GENSI and were randomly assigned to receive feedback about their network or not. The traditional questionnaire and GENSI took the same amount of time to complete, and measurements of racial composition of the network showed equivalent convergent validity in both survey tools. However, the new tool appears to solve what past researchers have considered to be a problem with online administration: exaggerated numbers of network connections. Moreover, respondents reported enjoying GENSI more than the traditional tool. Thus, using a graphical interface to collect ego-centered network data seems to be promising. However, telling respondents how their network compared to the average Americans reduced the convergent validity of measures administered after the feedback was provided, suggesting that such feedback should be avoided.     

A resample-replace lasso procedure for combining high-dimensional markers with limit of detection

In disease screening, a biomarker combination developed by combining multiple markers tends to have a higher sensitivity than an individual marker. Parametric methods for marker combination rely on the inverse of covariance matrices, which is often a non-trivial problem for high-dimensional data generated by modern high-throughput technologies. Additionally, another common problem in disease diagnosis is the existence of limit of detection (LOD) for an instrument – that is, when a biomarker''s value falls below the limit, it cannot be observed and is assigned an NA value. To handle these two challenges in combining high-dimensional biomarkers with the presence of LOD, we propose a resample-replace lasso procedure. We first impute the values below LOD and then use the graphical lasso method to estimate the means and precision matrices for the high-dimensional biomarkers. The simulation results show that our method outperforms alternative methods such as either substitute NA values with LOD values or remove observations that have NA values. A real case analysis on a protein profiling study of glioblastoma patients on their survival status indicates that the biomarker combination obtained through the proposed method is more accurate in distinguishing between two groups.