A simple method for constructing confounded designs for mixed factorial experiments

This paper presents the sinplesr procedure that uses wodular aryithmetic for constructing confounded designs for mixed factorial experiments. The present procedure and the classical one for confounding in symmetrical factorial experiments are both at the same mathema.tical level. The present procedure is written for

practitioners and is lllustrared with several examples.     

On the construction of orthogonal factorial designs of resolution 11

A new method of construction of orthogonal resolution IV designs for symmetrical and asymmetrical factorials has been presented. Many new series of orthogonal factorial designs of resolution IV can be obtained by the above general method.     

VARIATION REDUCTION AND ROBUST DESIGNS

In this paper we consider two strategies for variation reduction. One of them is the exploitation of interactions. We also discuss the role of experiments in discovering interactions and in particular the use of robust designs to obtain the interaction between control and noise factors. Then we attempt to reduce the variation in a measurement system using a robust design.     

A New Conjoint Analysis Procedure with Application to Marketing Research

Abstract

In this article we propose some extensions and applications of the nonparametric combination of dependent rankings (see Pesarin, F., Lago, A. (2000). Nonparametric combination of department rankings with applications to the quality assessment of industrial products. Metron LVIII (1–2):39–52.) This methodology is applied to Conjoint Analysis in order to aggregate (ex ante) preferences from a group of individuals. Furthermore, a new global association test (GAT) is introduced in order to test for the association of the global ranking with all attributes of interest. The GAT procedure allows the experimenter to have clear indications on significant attributes by considering the intensity of the optimal weights given by the procedure itself. This may help the experimenter in interpreting the usual analysis involving the normal plot for detecting active effects.     

A Variable Selection Method for Analyzing Supersaturated Designs

Supersaturated designs are a large class of factorial designs which can be used for screening out the important factors from a large set of potentially active variables. The huge advantage of these designs is that they reduce the experimental cost drastically, but their critical disadvantage is the confounding involved in the statistical analysis. In this article, we propose a method for analyzing data using several types of supersaturated designs. Modifications of widely used information criteria are given and applied to the variable selection procedure for the identification of the active factors. The effectiveness of the proposed method is depicted via simulated experiments and comparisons.     

D-Optimum Designs for Optimum Mixture in a Quadratic Log Contrast Model

Optimal designs for estimating the optimum mixing proportions in a quadratic mixture model was first investigated by Pal and Mandal (2006). In this article, similar investigation is carried out when mean response in a mixture experiment is described by a quadratic log contrast model. It is found that in a symmetric subspace of the finite dimensional simplex, there exists a D-optimal design that puts weights at the centroid of the sub-space and the vertices of the experimental domain. The optimality is checked by numerical computation using Equivalence Theorem.     

Statistical Inference of Adaptive Designs with Binary Responses

Adaptive designs of clinical trials are ethical alternatives when the traditional randomization becomes ethically infeasible in desperate medical situations. However, such a design creates a dependency among trial data and its statistical analysis becomes more complex than the analysis for traditional randomized clinical trials. In this article, we examine adaptive designs with dichotomous responses from two treatments and extend some commonly used statistical methods for independent data. Under a regularity condition, the estimated odds ratio and its logarithm are shown to follow asymptotically normal distributions. Moreover, the ordinary goodness-of-fit test statistic for two-by-two contingency tables with dependent data is shown to be asymptotically chi-square distributed. We also discuss the consistency of maximum likelihood estimators of the unknown parameters for a wide class of adaptive designs.     

D- and V-optimal population designs for the quadratic regression model with a random intercept term

In this paper D- and V-optimal population designs for the quadratic regression model with a random intercept term and with values of the explanatory variable taken from a set of equally spaced, non-repeated time points are considered. D-optimal population designs based on single-point individual designs were readily found but the derivation of explicit expressions for designs based on two-point individual designs was not straightforward and was complicated by the fact that the designs now depend on ratio of the variance components. Further algebraic results pertaining to d-point D-optimal population designs where d≥3 and to V-optimal population designs proved elusive. The requisite designs can be calculated by careful programming and this is illustrated by means of a simple example.     

A new lower bound to A2-optimality measure for multi-level and mixed-level column balanced designs and its applications

In this paper, a new lower bound to A₂-optimality measure is derived and is applied to multi-level and mixed-level column balanced designs. A₂-optimal multi-level and mixed-level designs are obtained by the application of the new lower bound.