Nonparametric monitoring of equal predictive ability

This paper introduces a novel sequential approach for online surveillance of the equal predictive ability (EPA) hypothesis presumed to hold for many competing forecasting models. A nonparametric control chart is suggested for providing a decision at every new time point as to whether the EPA hypothesis remains valid. The detection ability of our procedure is evaluated in a Monte Carlo simulation study for various types of deviations from the EPA hypothesis. Our approach enables the quick detection of various shift types, is parsimonious, and robust to misspecifications. Based on these results, we formulate practical recommendations for procedure design.     

胡尖山地区长 6、长 4+5 储层有利区预测

摘要：以胡尖山油田长 6、长 4+5 油藏为例,综合应用地质资料、岩芯分析资料、测井资料以及试油资料,开展了长 6和长 4+5 油藏小层划分和对比、单井相分析,建立测井相识别模式,编制小层沉积相平面展布图,进而分析沉积相演化规律;探讨储层砂体展布以及物性分布规律,从而深入认识研究区的储层特征。在此基础上对储层进行流动单元的划分,然后结合试油资料对胡尖山油田长 6、长 4+5 油藏的储层进行有利区域的预测,为油田待开发区域的合理建产开发提供了理论指导     

Adaptive designs for IVPT data with mixed scaled average bioequivalence

In vitro permeation tests (IVPT) offer accurate and cost-effective development pathways for locally acting drugs, such as topical dermatological products. For assessment of bioequivalence, the FDA draft guidance on generic acyclovir 5% cream introduces a new experimental design, namely the single-dose, multiple-replicate per treatment group design, as IVPT pivotal study design. We examine the statistical properties of its hypothesis testing method—namely the mixed scaled average bioequivalence (MSABE). Meanwhile, some adaptive design features in clinical trials can help researchers make a decision earlier with fewer subjects or boost power, saving resources, while controlling the impact on family-wise error rate. Therefore, we incorporate MSABE in an adaptive design combining the group sequential design and sample size re-estimation. Simulation studies are conducted to study the passing rates of the proposed methods—both within and outside the average bioequivalence limits. We further consider modifications to the adaptive designs applied for IVPT BE trials, such as Bonferroni's adjustment and conditional power function. Finally, a case study with real data demonstrates the advantages of such adaptive methods.     

PROPERTIES OF THE MINIMUM POINT OF AN UNBALANCED TWO-SIDED RANDOM WALK

In this paper, properties of minimum point of a unbalanced two-sided random walk are investigated. Under the condition that the parameters at both sides tend to zero at the same order, probabilities that the minimum point is on which side, and the second order expansions for the first two moments of the minimum point are obtained. Applications of these results are very promising. First, they can be used to study the properties of the maximum likelihood estimator for the change point in the large sample case; second, they can be used to study inference problems after CUSUM test.     

Score test for homogeneity of dispersion in generalized Poisson mixed models with excess zeros

In many applications, the clustered count data often contain excess zeros and the zero-inflated generalized Poisson mixed (ZIGPM) regression model may be suitable. However, dispersion in ZIGPM is often treated as fixed unknown parameter, and this assumption may be not appropriate in some situations. In this article, a score test for homogeneity of dispersion parameter in ZIGPM regression model is developed and corresponding test statistic is obtained. Sampling distribution and power of the score test statistic are investigated through Monte Carlo simulation. Finally, results from a biological example illustrate the usefulness of the diagnostic statistic.     

Tests for compound periodicities and estimating a non linear function

We propose two tests for testing compound periodicities which are the uniformly most powerful invariant decision procedures against simple periodicities. The second test can provide an excellent estimation of a compound periodic non linear function from observed data. These tests were compared with the tests proposed by Fisher and Siegel by Monte Carlo studies and we found that all the tests showed high power and high probability of a correct decision when all the amplitudes of underlying periods were the same. However, if there are at least several different periods with unequal amplitudes, then the second test proposed always showed high power and high probability of a correct decision, whereas the tests proposed by Fisher and Siegel gave 0 for the power and 0 for the probability of a correct decision, whatever the standard deviation of pseudo normal random numbers. Overall, the second test proposed is the best of all in view of the probability of a correct decision and power.     

Tests for Structural Changes in Time Series of Counts

We propose methods for detecting structural changes in time series with discrete‐valued observations. The detector statistics come in familiar L2‐type formulations incorporating the empirical probability generating function. Special emphasis is given to the popular models of integer autoregression and Poisson autoregression. For both models, we study mainly structural changes due to a change in distribution, but we also comment for the classical problem of parameter change. The asymptotic properties of the proposed test statistics are studied under the null hypothesis as well as under alternatives. A Monte Carlo power study on bootstrap versions of the new methods is also included along with a real data example.     

Strong law of large numbers and complete convergence for non-identically distributed WOD random variables

In this paper, we establish the strong law of large numbers and complete convergence for non-identically distributed WOD random variables. We derive some new inequalities of Fuk–Nagaev type for the sums of non-identically distributed WD random variables. All these results further extend and refine previous ones.