On Sharp Jensen's Inequality and Some Unusual Applications

The purpose of this article is two-fold. First, we find it very interesting to explore a kind of notion of optimality of the customary Jensen-bound among all Jensen-type bounds. Without this result, the customary Jensen-bound stood alone simply as just another bound. The proposed notion and the associated optimality are important given that in some situations the Jensen's inequality does leave us empty handed.

When it comes to highlighting Jensen's inequality, unfortunately only a handful of nearly routine applications continues to recycle time after time. Such encounters rarely produce any excitement. This article may change that outlook given its second underlying purpose, which is to introduce a variety of unusual applications of Jensen's inequality. The collection of our important and useful applications and their derivations are new.     

Adaptive Crossover Design for Normal Responses

In a response-adaptive design, we review and update the trial on the basis of outcomes in order to achive a specific goal. In clinical trials our goal is to allocate a larger number of patients to the better treatment. In the present paper, we use a response adaptive design in a two-treatment two-period crossover trial where the treatment responses are continuous. We provide probability measures to choose between the possible treatment combinations AA, AB, BA, or BB. The goal is to use the better treatment combination a larger number of times. We calculate the allocation proportions to the possible treatment combinations and their standard errors. We also derive some asymptotic results and provide solutions on related inferential problems. The proposed procedure is compared with a possible competitor. Finally, we use a data set to illustrate the applicability of our proposed design.     

Kernel Density-Based Linear Regression Estimate

For linear regression models with non normally distributed errors, the least squares estimate (LSE) will lose some efficiency compared to the maximum likelihood estimate (MLE). In this article, we propose a kernel density-based regression estimate (KDRE) that is adaptive to the unknown error distribution. The key idea is to approximate the likelihood function by using a nonparametric kernel density estimate of the error density based on some initial parameter estimate. The proposed estimate is shown to be asymptotically as efficient as the oracle MLE which assumes the error density were known. In addition, we propose an EM type algorithm to maximize the estimated likelihood function and show that the KDRE can be considered as an iterated weighted least squares estimate, which provides us some insights on the adaptiveness of KDRE to the unknown error distribution. Our Monte Carlo simulation studies show that, while comparable to the traditional LSE for normal errors, the proposed estimation procedure can have substantial efficiency gain for non normal errors. Moreover, the efficiency gain can be achieved even for a small sample size.     

Bonferroni-type Plug-in Procedure Controlling Generalized Familywise Error Rate

Consider the multiple hypotheses testing problem controlling the generalized familywise error rate k-FWER, the probability of at least k false rejections. We propose a plug-in procedure based on the estimation of the number of true null hypotheses. Under the independence assumption of the p-values corresponding to the true null hypotheses, we first introduce the least favorable configuration (LFC) of k-FWER for Bonferroni-type plug-in procedure, then we construct a plug-in k-FWER-controlled procedure based on LFC. For dependent p-values, we establish the asymptotic k-FWER control under some mild conditions. Simulation studies suggest great improvement over generalized Bonferroni test and generalized Holm test.     

On estimation of the mean parameter of a truncated normal disiribution with known coefficient of variation

This paper eals with the proplem on estimating the mean paramerer of a truncated normal distribution with known coefficient of variation. In the previous treatment of this problem most authors have used the sample standared deviation for estimating this parameter. In the present paper we use Gini’s coefficient of mean difference g and obtain the minimum variance unbiased estimate of the mean based on a linear function of the sample mean and g, It is shown that this new estimate has desirable properties for small samples as well as for large samples. We also give a numerical example.     

Bounds on deviations of estimates arising in finite population regression models

Bounds for the maximum deviation between parameters of a finite population and their corresponding sample estimates are found in the multiple regression model. The parameters considered are the vector of regression coefficients and the value ofthe regression function for given values of the independent variable (or variables). Applications are considered to several widely employed sampling methods.     

Structural properties and estimation in m|EK| 1 queue

In this paper we study the distribution of the number of customers served in a busy period in the framework of modified power series distribution introduced by Gupta (197U) and obtain the moments and probability generating function of this distribution. We also study the maximum likelihood estimation of the parameter θand the variance and the asymptotic bias of the MLE are also obtained. The minimum variance unbiased estimate of θ^ris investigated and an estimate of the probabilities is given.     

Nonparametric estimation of the survival distribution in censored data

Two nonparametric estimators o f the survival distributionare discussed. The estimators were proposed by Kaplan and Meier (1958) and Breslow (1972) and are applicable when dealing with censored data. It is known that they are asymptotically unbiased and uniformly strongly consistent, and when properly normalized that they converge weakly to the same Gaussian process. In this paper, the properties of the estimators are carefully inspected in small or moderate samples. The Breslow estimator, a shrinkage version of the Kaplan-Meier, nearly always has the smaller mean square error (MSE) whenever the truesurvival probabilityis at least 0.20, but has considerably larger MSE than the Kaplan-Meier estimator when the survivalprobability is near zero.