Tests of serial independence based on Kendall's process

The authors propose new rank statistics for testing the white noise hypothesis in a time series. These statistics are Cramér‐von Mises and Kolmogorov‐Smirnov functionals of an empirical distribution function whose mean is related to a serial version of Kendall's tau through a linear transform. The authors determine the asymptotic behaviour of the underlying serial process and the large‐sample distribution of the proposed statistics under the null hypothesis of white noise. They also present simulation results showing the power of their tests.     

Confidence bands from censored samples

Several types of asymptotic confidence bands have been proposed in the literature when the data are randomly censored on the right. Introducing new classes of bands, we place the old bands and their relationship to one another within a comprehensive theory of bands. A thorough analysis yields narrower bands and two kinds of modifications which are asymptotically distribution- and censor-free. One of these is useful when the interval on which the bands are constructed is predetermined and the width of the bands is random; the other, when there is a predetermined bound on the width and the interval is random. We illustrate our bands on the Szeged pacemaker data. These methods also provide a general modification of the Kolmogorov band in the uncensored case.     

Two-Sample Tests Based on the Integrated Empirical Process

Abstract

Let X ₁, …, X _m and Y ₁, …, Y _n be independent random variables, where X ₁, …, X _m are i.i.d. with continuous distribution function (df) F, and Y ₁, …, Y _n are i.i.d. with continuous df G. For testing the hypothesis H ₀: F = G, we introduce and study analogues of the celebrated Kolmogorov–Smirnov and one- and two-sided Cramér-von Mises statistics that are functionals of a suitably integrated two-sample empirical process. Furthermore, we characterize those distributions for which the new tests are locally Bahadur optimal within the setting of shift alternatives.     

Goodness-of-Fit Test and Parameter Estimation for a Proportional Odds Model of Random Censorship

Censored data arise naturally in a number of fields, particularly in problems of reliability and survival analysis. There are several types of censoring, in this article, we will confine ourselves to the right randomly censoring type. Recently, Ahmadi et al. (2010 Ahmadi , J. , Doostparast , M. , Parsian , A. ( 2010 ). Bayes estimation based on random censored data for some life time models under symmetric and asymmetric loss functions . Communcations in Statistics-Theory and Methods , 39 : 3058 – 3071 .[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]) considered the problem of estimating unknown parameters in a general framework based on the right randomly censored data. They assumed that the survival function of the censoring time is free of the unknown parameter. This assumption is sometimes inappropriate. In such cases, a proportional odds (PO) model may be more appropriate (Lam and Leung, 2001 Lam , K. F. , Leung , T. L. ( 2001 ). Marginal likelihood estimation for proportional odds models with right censored data . Lifetime Data Analysis 7 : 39 – 54 .[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). Under this model, in this article, point and interval estimations for the unknown parameters are obtained. Since it is important to check the adequacy of models upon which inferences are based (Lawless, 2003 Lawless , J. F. (2003). Statistical Models and Methods for Lifetime Data. , 2nd ed. New York : John Wiley & Sons. [Google Scholar], p. 465), two new goodness-of-fit tests for PO model based on right randomly censored data are proposed. The proposed procedures are applied to two real data sets due to Smith (2002 Smith , P. J. ( 2002 ). Analysis of Failure and Survival Data . London : Chapman & Hall, CRC . [Google Scholar]). A Monte Carlo simulation study is conducted to carry out the behavior of the estimators obtained.     

Discriminating between the Weibull and log-normal distributions for Type-II censored data

Log-normal and Weibull distributions are the two most popular distributions for analysing lifetime data. In this paper, we consider the problem of discriminating between the two distribution functions. It is assumed that the data are coming either from log-normal or Weibull distributions and that they are Type-II censored. We use the difference of the maximized log-likelihood functions, in discriminating between the two distribution functions. We obtain the asymptotic distribution of the discrimination statistic. It is used to determine the probability of correct selection in this discrimination process. We perform some simulation studies to observe how the asymptotic results work for different sample sizes and for different censoring proportions. It is observed that the asymptotic results work quite well even for small sizes if the censoring proportions are not very low. We further suggest a modified discrimination procedure. Two real data sets are analysed for illustrative purposes.     

Performance of the One-Sample Goodness-of-Fit P–P-Plot Length Test

This article studies the performance of the one-sample goodness-of-fit test which is based on the length of the P–P-plot initially introduced in a similar context by Reschenhofer and Bomze (1991 Reschenhofer , E. , Bomze , I. M. ( 1991 ). Length tests for goodness-of-fit . Biometrika 78 : 207 – 216 . [Google Scholar]). The distributional properties of the length test are revised empirically via simulations. In the Monte Carlo power study that follows the length test is shown empirically to have high power under various alternatives considered relative to members of the Cramér–von Mises family of goodness-of-fit tests, and the Kolmogorov–Smirnov test.     

Kolmogorov–Smirnov,Fluctuation, and Z g Tests for Convergence of Markov Chain Monte Carlo Draws

We examine the sizes and powers of three tests of convergence of Markov Chain Monte Carlo draws: the Kolmogorov–Smirnov test, fluctuation test, and Geweke's test. We show that the sizes and powers are sensitive to the existence of autocorrelation in the draws. We propose a filtered test that is corrected for autocorrelation. We present a numerical illustration using the Federal funds rate.     

Regional efficacy evaluation in multi-regional clinical trials using a discounting factor weighted Z test

Multi-regional clinical trial (MRCT) is an efficient design to accelerate drug approval globally. Once the global efficacy of test drug is demonstrated, each local regulatory agency is required to prove effectiveness of test drug in their own population. Meanwhile, the ICH E5/E17 guideline recommends using data from other regions to help evaluate regional drug efficacy. However, one of the most challenges is how to manage to bridge data among multiple regions in an MRCT since various intrinsic and extrinsic factors exist among the participating regions. Furthermore, it is critical for a local agency to determine the proportion of information borrowing from other regions given the ethnic differences between target region and non-target regions. To address these issues, we propose a discounting factor weighted Z statistic to adaptively borrow information from non-target regions. In this weighted Z statistic, the weight is derived from a discounting factor in which the discounting factor denotes the proportion of information borrowing from non-target regions. We consider three ways to construct discounting factors based on the degree of congruency between target and non-target regions either using control group data, or treatment group data, or all data. We use the calibrated power prior to construct discounting factor based on scaled Kolmogorov–Smirnov statistic. Comprehensive simulation studies show that our method has desirable operating characteristics. Two examples are used to illustrate the applications of our proposed approach.     

Asymptotically optimal Berry-Esseen-type bounds for distributions with an absolutely continuous part

Recursive and closed form upper bounds are offered for the Kolmogorov and the total variation distance between the standard normal distribution and the distribution of a standardized sum of n independent and identically distributed random variables. The method employed is a modification of the method of compositions along with Zolotarev's ideal metric. The approximation error in the CLT obtained vanishes at a rate O(n^−k/2+1), provided that the common distribution of the summands possesses an absolutely continuous part, and shares the same k−1 (k?3) first moments with the standard normal distribution. Moreover, for the first time, these new uniform Berry-Esseen-type bounds are asymptotically optimal, that is, the ratio of the true distance to the respective bound converges to unity for a large class of distributions of the summands. Thus, apart from the correct rate, the proposed error estimates incorporate an optimal asymptotic constant (factor). Finally, three illustrative examples are presented along with numerical comparisons revealing that the new bounds are sharp enough even to be used in practical statistical applications.     

Goodness-of-fit tests based on the distance between the Dirichlet process and its base measure

The Dirichlet process is a fundamental tool in studying Bayesian nonparametric inference. The Dirichlet process has several sum representations, where each one of these representations highlights some aspects of this important process. In this paper, we use the sum representations of the Dirichlet process to derive explicit expressions that are used to calculate Kolmogorov, Lévy, and Cramér–von Mises distances between the Dirichlet process and its base measure. The derived expressions of the distance are used to select a proper value for the concentration parameter of the Dirichlet process. These tools are also used in a goodness-of-fit test. Illustrative examples and simulation results are included.