Estimation in an empirical bayes model for longitudinal and cross‐sectionally clustered binary data

Some studies generate data that can be grouped into clusters in more than one way. Consider for instance a smoking prevention study in which responses on smoking status are collected over several years in a cohort of students from a number of different schools. This yields longitudinal data, also cross‐sectionaliy clustered in schools. The authors present a model for analyzing binary data of this type, combining generalized estimating equations and estimation of random effects to address the longitudinal and cross‐sectional dependence, respectively. The estimation procedure for this model is discussed, as are the results of a simulation study used to investigate the properties of its estimates. An illustration using data from a smoking prevention trial is given.     

一类二阶拟线性微分方程的非振动定理

考虑二阶拟线性微分方程 :( |y′|α -1y′)′+q(t) |y|α -1y=0 ,获得了在 q(t)振动的条件下该方程非振动的一些充分 (必要 )条件 ,改进和推广了已有文献的结果     

Book Reviews

Books reviewed:
Philip Hans Franses & Dick van Dijk, Non-linear Time Series Models in Empirical Finance
Herbert Spirer, Louise Spirer & A.J. Jaffe, Misused Statistics
Deborah J. Bennett, Randomness
C.E. Linneborg, Data Analysis by Resampling: Concepts and Applications
I. Clark and W.V. Harper, Practical Geostatistics 2000     

一类地下水水质污染问题广义解的唯一性及对初值和自由项的连续依赖性

本文讨论了一类地下水水质污染问题，其数学模型为一组非线性双曲—抛物耦合方程组，并证明了在相应初边值条件下广义解的唯一性及对初值和自由项的连续依赖性．     

Evaluation of an analysis approach used to account for extra-variation in clustered categorical responses

This article presents the results of a simulation study investigating the performance of an approach developed by Miller and Landis (1991) for the analysis of clustered categorical responses. Evaluation of this “two-step” approach, which utilizes the method of moments to estimate the extra-variation pardmeters and subsequently incorporates these parameters into estimating equations for modelling the marginal expectations, is carried out in an experimental setting involving a comparison between two groups of observations. We assume that data for both groups are collected from each cluster and responses are measured on a three-point ordinal scale. The performance of the estimators used in both “steps” of the analysisis investigated and comparisons are made to an alternative analysismethod that ignores the clustering. The results indicate that in the chosen setting the test for a difference between groups generally operatbs at the nominal α=0.05 for 10 or more clusters and hasincreasing power with both an increasing number of clusters and an inrreasing treatment effect. These results provide a striking contrasc to those obtained from an improper analysis that ignores clustering.     

Estimable functions in the nonlinear model

When the method of least squares is used to estimate the parameters in a general model and the generated system of normal equations is linearly dependent, the estimate of the vector of parameters which satisfies the criterion is not unique. However, there exist certain functions of the estimated vector of parameters which are invariant to the least squares solution obtained from the normal equations. We define those invariant functions to be estimable, and present a technique to determine the functions of the parameters which are estimable for the general model. The method results in solving either a linear first order partial differential equation or a system of linear first order partial differential equations corresponding, respectively, to a single or multiple dependency between columns of the Jacobian matrix of the mean of the model. The usual results concerning estimability for linear models are a special case of the general results developed.     

Nonparametric estimating equations based on a penalized information criterion

It has recently been observed that, given the mean‐variance relation, one can improve on the accuracy of the quasi‐likelihood estimator by the adaptive estimator based on the estimation of the higher moments. The estimation of such moments is usually unstable, however, and consequently only for large samples does the improvement become evident. The author proposes a nonparametric estimating equation that does not depend on the estimation of such moments, but instead on the penalized minimization of asymptotic variance. His method provides a strong improvement over the quasi‐likelihood estimator and the adaptive estimators, for a wide range of sample sizes.     

一类一阶线性方程组的解法

利用复系数的一阶线性方程解公式，给出一类一阶线性方程组的新解性。     

Simplified Estimating Functions for Diffusion Models with a High-dimensional Parameter

We consider estimating functions for discretely observed diffusion processes of the following type: for one part of the parameter of interest we propose to use a simple and explicit estimating function of the type studied by Kessler (2000); for the remaining part of the parameter we use a martingale estimating function. Such an approach is particularly useful in practical applications when the parameter is high-dimensional. It is also often necessary to supplement a simple estimating function by another type of estimating function because only the part of the parameter on which the invariant measure depends can be estimated by a simple estimating function. Under regularity conditions the resulting estimators are consistent and asymptotically normal. Several examples are considered in order to demonstrate the idea of the estimating procedure. The method is applied to two data sets comprising wind velocities and stock prices. In one example we also propose a general method for constructing diffusion models with a prescribed marginal distribution which have a flexible dependence structure.     

线性抛物型方程的窄四边形元逼近方法

讨论了一类发展方程——线性抛物型方程的窄四边形元逼近方法,导出了相应的半离散格式和全离散格式,并通过一些新的技巧,得到了相应的误差估计.