Plotting of log−log survival functions against time for different categories or combinations of categories of covariates is perhaps the easiest and most commonly used graphical tool for checking proportional hazards (PH) assumption. One problem in the utilization of the technique is that the covariates need to be categorical or made categorical through appropriate grouping of the continuous covariates. Subjectivity in the decision making on the basis of eye-judgment of the plots and frequent inconclusiveness arising in situations where the number of categories and/or covariates gets larger are among other limitations of this technique. This paper proposes a non-graphical (numerical) test of the PH assumption that makes use of log−log survival function. The test enables checking proportionality for categorical as well as continuous covariates and overcomes the other limitations of the graphical method. Observed power and size of the test are compared to some other tests of its kind through simulation experiments. Simulations demonstrate that the proposed test is more powerful than some of the most sensitive tests in the literature in a wide range of survival situations. An example of the test is given using the widely used gastric cancer data. 相似文献
Over the past five years the Artificial Intelligence Center at SRI has been developing a new technology to address the problem of automated information management within real- world contexts. The result of this work is a body of techniques for automated reasoning from evidence that we call evidential reasoning. The techniques are based upon the mathematics of belief functions developed by Dempster and Shafer and have been successfully applied to a variety of problems including computer vision, multisensor integration, and intelligence analysis.
We have developed both a formal basis and a framework for implementating automated reasoning systems based upon these techniques. Both the formal and practical approach can be divided into four parts: (1) specifying a set of distinct propositional spaces, (2) specifying the interrelationships among these spaces, (3) representing bodies of evidence as belief distributions, and (4) establishing paths of the bodies for evidence to move through these spaces by means of evidential operations, eventually converging on spaces where the target questions can be answered. These steps specify a means for arguing from multiple bodies of evidence toward a particular (probabilistic) conclusion. Argument construction is the process by which such evidential analyses are constructed and is the analogue of constructing proof trees in a logical context.
This technology features the ability to reason from uncertain, incomplete, and occasionally inaccurate information based upon seven evidential operations: fusion, discounting, translation, projection, summarization, interpretation, and gisting. These operation are theoretically sound but have intuitive appeal as well.
In implementing this formal approach, we have found that evidential arguments can be represented as graphs. To support the construction, modification, and interrogation of evidential arguments, we have developed Gister. Gister provides an interactive, menu-driven, graphical interface that allows these graphical structures to be easily manipulated.
Our goal is to provide effective automated aids to domain experts for argument construction. Gister represents our first attempt at such an aid. 相似文献
In this article, we propose a weighted simulated integrated conditional moment (WSICM) test of the validity of parametric specifications of conditional distribution models for stationary time series data, by combining the weighted integrated conditional moment (ICM) test of Bierens (1984Bierens, H. J. (1984). Model specification testing of time series regressions. Journal of Econometrics 26:323–353.[Crossref], [Web of Science ®], [Google Scholar]) for time series regression models with the simulated ICM test of Bierens and Wang (2012Bierens, H. J., Wang, L. (2012). Integrated conditional moment tests for parametric conditional distributions. Econometric Theory 28:328–362.[Crossref], [Web of Science ®], [Google Scholar]) of conditional distribution models for cross-section data. To the best of our knowledge, no other consistent test for parametric conditional time series distributions has been proposed yet in the literature, despite consistency claims made by some authors. 相似文献
Several researchers have proposed solutions to control type I error rate in sequential designs. The use of Bayesian sequential design becomes more common; however, these designs are subject to inflation of the type I error rate. We propose a Bayesian sequential design for binary outcome using an alpha‐spending function to control the overall type I error rate. Algorithms are presented for calculating critical values and power for the proposed designs. We also propose a new stopping rule for futility. Sensitivity analysis is implemented for assessing the effects of varying the parameters of the prior distribution and maximum total sample size on critical values. Alpha‐spending functions are compared using power and actual sample size through simulations. Further simulations show that, when total sample size is fixed, the proposed design has greater power than the traditional Bayesian sequential design, which sets equal stopping bounds at all interim analyses. We also find that the proposed design with the new stopping for futility rule results in greater power and can stop earlier with a smaller actual sample size, compared with the traditional stopping rule for futility when all other conditions are held constant. Finally, we apply the proposed method to a real data set and compare the results with traditional designs. 相似文献
In this exploratory study, we examine whether organizational mission statement attributes make a difference to the performance of nonprofit performing arts organizations. We use text analysis to measure two semantic attributes—activity and commonality—of mission statements. We examine whether these attributes are associated with improved performance for the instrumental and expressive functions of nonprofit performing arts organizations. Our findings indicate that the mission statement attribute activity is associated with improved performance for both instrumental and expressive functions. Our analysis of nonfindings for the mission statement attribute commonality suggests that there is a need to develop and use content analysis tools tailored to nonprofit contexts. 相似文献
In this paper, we consider a generalisation of the backward simulation method of Duch et al. [New approaches to operational risk modeling. IBM J Res Develop. 2014;58:1–9] to build bivariate Poisson processes with flexible time correlation structures, and to simulate the arrival times of the processes. The proposed backward construction approach uses the Marshall–Olkin bivariate binomial distribution for the conditional law and some well-known families of bivariate copulas for the joint success probability in lieu of the typical conditional independence assumption. The resulting bivariate Poisson process can exhibit various time correlation structures which are commonly observed in real data. 相似文献