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41.
A Multivariate Model for Repeated Failure Time Measurements   总被引:1,自引:1,他引:0  
A parametric multivariate failure time distribution is derived from a frailty-type model with a particular frailty distribution. It covers as special cases certain distributions which have been used for multivariate survival data in recent years. Some properties of the distribution are derived: its marginal and conditional distributions lie within the parametric family, and association between the component variates can be positive or, to a limited extent, negative. The simple closed form of the survivor function is useful for right-censored data, as occur commonly in survival analysis, and for calculating uniform residuals. Also featured is the distribution of ratios of paired failure times. The model is applied to data from the literature  相似文献   
42.
A common problem in environmental epidemiology is the estimation and mapping of spatial variation in disease risk. In this paper we analyse data from the Walsall District Health Authority, UK, concerning the spatial distributions of cancer cases compared with controls sampled from the population register. We formulate the risk estimation problem as a nonparametric binary regression problem and consider two different methods of estimation. The first uses a standard kernel method with a cross-validation criterion for choosing the associated bandwidth parameter. The second uses the framework of the generalized additive model (GAM) which has the advantage that it can allow for additional explanatory variables, but is computationally more demanding. For the Walsall data, we obtain similar results using either the kernel method with controls stratified by age and sex to match the age–sex distribution of the cases or the GAM method with random controls but incorporating age and sex as additional explanatory variables. For cancers of the lung or stomach, the analysis shows highly statistically significant spatial variation in risk. For the less common cancers of the pancreas, the spatial variation in risk is not statistically significant.  相似文献   
43.
This paper describes a technique for computing approximate maximum pseudolikelihood estimates of the parameters of a spatial point process. The method is an extension of Berman & Turner's (1992) device for maximizing the likelihoods of inhomogeneous spatial Poisson processes. For a very wide class of spatial point process models the likelihood is intractable, while the pseudolikelihood is known explicitly, except for the computation of an integral over the sampling region. Approximation of this integral by a finite sum in a special way yields an approximate pseudolikelihood which is formally equivalent to the (weighted) likelihood of a loglinear model with Poisson responses. This can be maximized using standard statistical software for generalized linear or additive models, provided the conditional intensity of the process takes an 'exponential family' form. Using this approach a wide variety of spatial point process models of Gibbs type can be fitted rapidly, incorporating spatial trends, interaction between points, dependence on spatial covariates, and mark information.  相似文献   
44.
Differential equations have been used in statistics to define functions such as probability densities. But the idea of using differential equation formulations of stochastic models has a much wider scope. The author gives several examples, including simultaneous estimation of a regression model and residual density, monotone smoothing, specification of a link function, differential equation models of data, and smoothing over complicated multidimensional domains. This paper aims to stimulate interest in this approach to functional estimation problems, rather than provide carefully worked out methods.  相似文献   
45.
This paper concerns the geometric treatment of graphical models using Bayes linear methods. We introduce Bayes linear separation as a second order generalised conditional independence relation, and Bayes linear graphical models are constructed using this property. A system of interpretive and diagnostic shadings are given, which summarise the analysis over the associated moral graph. Principles of local computation are outlined for the graphical models, and an algorithm for implementing such computation over the junction tree is described. The approach is illustrated with two examples. The first concerns sales forecasting using a multivariate dynamic linear model. The second concerns inference for the error variance matrices of the model for sales, and illustrates the generality of our geometric approach by treating the matrices directly as random objects. The examples are implemented using a freely available set of object-oriented programming tools for Bayes linear local computation and graphical diagnostic display.  相似文献   
46.
外语教师队伍建设要从改变教师的传统教育理念,加强专业理论知识学习,提高教师的反思意识,研究教师的发展模式等方面入手,引导培养青年教师向学者型教师发展。  相似文献   
47.
In this article, we first propose the modified Hannan–Rissanen Method for estimating the parameters of autoregressive moving average (ARMA) process with symmetric stable noise and symmetric stable generalized autoregressive conditional heteroskedastic (GARCH) noise. Next, we propose the modified empirical characteristic function method for the estimation of GARCH parameters with symmetric stable noise. Further, we show the efficiency, accuracy and simplicity of our methods with Monte-Carlo simulation. Finally, we apply our proposed methods to model the financial data.  相似文献   
48.
本文从政治学资源配置的角度概括了公共管理模式的本质与特征、分析公共管理模式嬗变的理论根源和实践背景,并结合当前正在发生的金融危机探讨公共管理模式的流变及方向,力图揭示当今公共管理在资源配置机制上的变化规律和最新特征。  相似文献   
49.
"有限元分析"是工程领域进行数值计算的极为重要的方法之一。为使学生掌握有限元方法的基本原理和编程技巧,更好地应用有限元分析这一强有力的数值计算工具,文章将理论分析、传统实验与计算机数值模拟有机结合,结合工程应用的具体实践,在有限元教学中不断渗透学科发展的前沿知识,从教学方式、内容选择、实验设计等几个方面作了一系列探索。  相似文献   
50.
In this article we develop a nonparametric estimator for the local average response of a censored dependent variable to endogenous regressors in a nonseparable model where the unobservable error term is not restricted to be scalar and where the nonseparable function need not be monotone in the unobservables. We formalize the identification argument put forward in Altonji, Ichimura, and Otsu (2012 Altonji, J. G., Ichimura, H., Otsu, T. (2012). Estimating derivatives in nonseparable models with limited dependent variables. Econometrica 80:17011719.[Crossref], [Web of Science ®] [Google Scholar]), construct a nonparametric estimator, characterize its asymptotic property, and conduct a Monte Carlo investigation to study its small sample properties. Identification is constructive and is achieved through a control function approach. We show that the estimator is consistent and asymptotically normally distributed. The Monte Carlo results are encouraging.  相似文献   
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